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Esther Pérez-Navarro

Esther Pérez-Navarro

D-Index & Metrics

Neuroscience

D-Index
38
Citations
4489
World Ranking
8635
National Ranking
140

Overview

Esther Pérez-Navarro is affiliated with the University of Barcelona in Spain. Their research primarily focuses on the intersection of biochemistry, genetics, molecular biology, neuroscience, and medicine, with a substantial body of work addressing neurodegenerative diseases and cellular mechanisms.

The main fields of study in which they publish most frequently include:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience
  • Medicine

The scientist's work delves deeply into several subfields, including:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Neurology
  • Cancer Research
  • Physiology

The key topics that characterize their research include:

  • Genetic Neurodegenerative Diseases
  • Mitochondrial Function and Pathology
  • Neurological disorders and treatments
  • Extracellular vesicles in disease
  • Nuclear Structure and Function
  • RNA Research and Splicing
  • Neuroinflammation and Neurodegeneration Mechanisms

Among their recent publications are several papers that emphasize neurodegenerative disorders, particularly Huntington's disease, and the role of cellular components such as extracellular vesicles and molecular signaling in neural function. Notable papers include:

  • Neuron type-specific increase in lamin B1 contributes to nuclear dysfunction in Huntington's disease, 2020, EMBO Molecular Medicine
  • Neuron-derived extracellular vesicles contain synaptic proteins, promote spine formation, activate TrkB-mediated signalling and preserve neuronal complexity, 2023, Journal of Extracellular Vesicles
  • Huntington's disease brain-derived small RNAs recapitulate associated neuropathology in mice, 2021, Acta Neuropathologica
  • Synaptic RTP801 contributes to motor-learning dysfunction in Huntington's disease, 2020, Cell Death and Disease
  • RTP801 mediates transneuronal toxicity in culture via extracellular vesicles, 2023, Journal of Extracellular Vesicles

Their research has been published in multiple academic venues, with frequent contributions to:

  • Journal of Extracellular Vesicles
  • American Journal Of Pathology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • EMBO Molecular Medicine

Esther Pérez-Navarro has collaborated extensively within their field. Frequent coauthors include:

  • Jordi Alberch
  • Cristina Malagelada
  • Júlia Solana-Balaguer
  • Genís Campoy-Campos
  • Leticia Pérez-Sisqués

Best Publications

  • Caveolin-1 deficiency causes cholesterol dependent mitochondrial dysfunction and apoptotic susceptibility

    Marta Bosch;Montserrat Marí;Albert Herms;Ana Fernández

  • Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease.

    Esther Pérez‐Navarro;Anna M. Canudas;Peter Åkerud;Jordi Alberch

  • Increased 5-Methylcytosine and Decreased 5-Hydroxymethylcytosine Levels are Associated with Reduced Striatal A2AR Levels in Huntington’s Disease

    Izaskun Villar-Menéndez;Marta Blanch;Shiraz Tyebji;Thais Pereira-Veiga

  • Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease

    Albert Giralt;Ana Saavedra;Olga Carretón;Xavier Xifró

  • Neuroprotection by neurotrophins and GDNF family members in the excitotoxic model of Huntington's disease

    J Alberch;E Pérez-Navarro;J.M Canals

  • Neurokinin receptors differentially mediate endogenous acetylcholine release evoked by tachykinins in the neostriatum

    Ernest Arenas;Jordi Alberch;Esther Perez-Navarro;Carles Solsona

  • Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area.

    Josep M. Canals;Núria Checa;Sònia Marco;Peter Åkerud

  • Glial cell line-derived neurotrophic factor protects striatal calbindin-immunoreactive neurons from excitotoxic damage

    E Pérez-Navarro;E Arenas;J Reiriz;N Calvo

  • Neurotrophic factors in Huntington's disease.

    Jordi Alberch;Esther Pérez-Navarro;Josep M Canals

  • Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members

    Elena Gratacòs;Esther Pérez-Navarro;Eduard Tolosa;Ernest Arenas

  • Both apoptosis and necrosis occur following intrastriatal administration of excitotoxins

    I. Ferrer;F. Martin;T. Serrano;J. Reiriz

  • PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a Huntington's disease mouse model

    Albert Giralt;Ana Saavedra;Olga Carretón;Helena Arumí

  • Brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4/5 differentially regulate the phenotype and prevent degenerative changes in striatal projection neurons after excitotoxicity in vivo.

    E Pérez-Navarro;J Alberch;I Neveu;E Arenas

  • Brain-derived neurotrophic factor prevents changes in Bcl-2 family members and caspase-3 activation induced by excitotoxicity in the striatum.

    Esther Pérez-Navarro;Núria Gavaldà;Elena Gratacòs;Jordi Alberch

  • Cognitive Dysfunction in Huntington's Disease: Humans, Mouse Models and Molecular Mechanisms.

    Albert Giralt;Ana Saavedra;Jordi Alberch;Esther Pérez-Navarro

  • Bax and Calpain Mediate Excitotoxic Oligodendrocyte Death Induced by Activation of Both AMPA and Kainate Receptors

    María Victoria Sánchez-Gómez;Elena Alberdi;Esther Pérez-Navarro;Jordi Alberch

  • Targeting CAG repeat RNAs reduces Huntington’s disease phenotype independently of huntingtin levels

    Laura Rué;Mónica Bañez-Coronel;Jordi Creus-Muncunill;Albert Giralt

  • Involvement of nerve growth factor and its receptor in the regulation of the cholinergic function in aged rats.

    Alberch J;Pérez-Navarro E;Arenas E;Marsal J

  • Intrastriatal grafting of a GDNF-producing cell line protects striatonigral neurons from quinolinic acid excitotoxicity in vivo.

    E. Pérez‐Navarro;E. Arenas;S. Marco;J. Alberch

  • PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum

    A Saavedra;J M García-Martínez;J M García-Martínez;X Xifró;A Giralt

  • Regulation of hippocampal cGMP levels as a candidate to treat cognitive deficits in Huntington's disease.

    Ana Saavedra;Albert Giralt;Helena Arumí;Jordi Alberch

Frequent Co-Authors

Jordi Alberch
Jordi Alberch University of Barcelona
Josep M. Canals
Josep M. Canals University of Barcelona
Agnès Gruart
Agnès Gruart Pablo de Olavide University
José M. Delgado-García
José M. Delgado-García Pablo de Olavide University
Paul J. Lombroso
Paul J. Lombroso Yale University
Eduardo D. Martín
Eduardo D. Martín Yale School of Medicine
Anna M. Planas
Anna M. Planas Spanish National Research Council
Ferran Martin
Ferran Martin Autonomous University of Barcelona
Derek J. Blake
Derek J. Blake Cardiff University

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Related Online Degrees & Career Pathways

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Alternatively, a masters in psychology can deepen your understanding of the brain, behavior, and mental processes, preparing you for roles in research, clinical settings, or academia.

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