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2025
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Biology and Biochemistry
Canada
2026

D-Index & Metrics

Best Scientists

D-Index
167
Citations
103835
World Ranking
978
National Ranking
21

Biology and Biochemistry

D-Index
169
Citations
105199
World Ranking
93
National Ranking
4

Medicine

D-Index
169
Citations
105312
World Ranking
544
National Ranking
13

Michael R. Hayden publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Michael R. Hayden sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 992 publications — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Michael R. Hayden D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Michael R. Hayden sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 169 D-Index — 100th percentile

100% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2023 - Research.com Medicine in Canada Leader Award
  • 2022 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2011 - Izaak Walton Killam Memorial Prize, Canada Council
  • 2011 - Canada Gairdner Wightman Award
  • 1995 - Fellow of the Royal Society of Canada Academy of Science

Overview

Michael R. Hayden is affiliated with the University of British Columbia in Canada, focusing on research that spans biochemistry, genetics, molecular biology, neuroscience, and medicine. Their work mainly addresses genetic neurodegenerative diseases and explores molecular and cellular mechanisms underlying neurological disorders.

The primary fields of study for this researcher include:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience
  • Medicine

Within these domains, their subfields of study concentrate on:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Neurology
  • Genetics
  • Oncology

Key topics covered in their publications involve:

  • Genetic Neurodegenerative Diseases
  • Mitochondrial Function and Pathology
  • Neurological disorders and treatments
  • Pharmacological Receptor Mechanisms and Effects
  • Neuroscience and Neuropharmacology Research
  • Muscle Physiology and Disorders
  • Amyotrophic Lateral Sclerosis Research

Their publication record includes frequent appearances in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurology
  • Neurobiology of Disease
  • Journal of Huntington's Disease
  • Neurotherapeutics

Michael R. Hayden has collaborated extensively with several researchers including:

  • Michal Geva
  • Nicholas S. Caron
  • Hailey Findlay Black
  • Blair R. Leavitt
  • Amber L. Southwell

Among recent research publications, notable papers are:

  • Small molecule splicing modifiers with systemic HTT-lowering activity, 2021, Nature Communications
  • Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies, 2020, The Lancet Neurology
  • Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease, 2020, Journal of Neuroscience
  • The Sigma-1 Receptor Mediates Pridopidine Rescue of Mitochondrial Function in Huntington Disease Models, 2021, Neurotherapeutics
  • Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine, 2022, Autophagy

The researcher's recognition includes awards such as the Izaak Walton Killam Memorial Prize by the Canada Council in 2011, the Canada Gairdner Wightman Award also in 2011, and election as a Fellow of the Royal Society of Canada in 1995 within the Academy of Science.

Best Publications

  • Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

    A. Brooks-Wilson;M. Marcil;S. M. Clee;L.-H. Zhang

  • Loss of Huntingtin-Mediated BDNF Gene Transcription in Huntington's Disease

    Chiara Zuccato;Andrea Ciammola;Dorotea Rigamonti;Blair R. Leavitt

  • Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines

    Alexander V. Panov;Claire-Anne Gutekunst;Blair R. Leavitt;Michael R. Hayden

  • Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis.

    George Papanikolaou;Mark E Samuels;Erwin H Ludwig;Marcia L E MacDonald

  • Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.

    Chiara Zuccato;Marzia Tartari;Andrea Crotti;Donato Goffredo

  • Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes.

    Jamal Nasir;Stan B Floresco;John R O'Kusky;Virginia M Diewert

  • A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

    J.Graeme Hodgson;Nadia Agopyan;Claire-Anne Gutekunst;Blair R Leavitt

  • Detection of Huntington’s disease decades before diagnosis: The Predict HD study

    Jane Paulsen;Douglas R Langbehn;Julie C Stout;Elizabeth H Aylward

  • Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

    Elizabeth J. Slow;Jeremy van Raamsdonk;Daniel Rogers;Sarah H. Coleman

  • A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length.

    Douglas R. Langbehn;Ryan R. Brinkman;Daniel Falush;Jane S. Paulsen

  • Aspirin for the Primary Prevention of Cardiovascular Events: A Summary of the Evidence for the U.S. Preventive Services Task Force

    Michael Hayden;Michael Pignone;Christopher Phillips;Cynthia Mulrow

  • A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.

    Shinji Hadano;Collette K. Hand;Hitoshi Osuga;Yoshiko Yanagisawa

  • Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin.

    Rona K. Graham;Yu Deng;Elizabeth J. Slow;Brendan Haigh

  • Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract.

    Y.P. Goldberg;D.W. Nicholson;D.M. Rasper;M.A. Kalchman

  • A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

    Maria Björkqvist;Edward J. Wild;Jenny Thiele;Aurelio Silvestroni

  • Increased Sensitivity to N-Methyl-D-Aspartate Receptor-Mediated Excitotoxicity in a Mouse Model of Huntington's Disease.

    Melinda M Zeron;Oskar Hansson;Nansheng Chen;Cheryl L Wellington

  • Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats.

    Rubinsztein Dc;Leggo J;Coles R;Almqvist E

  • Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract

    Cheryl L. Wellington;Lisa M. Ellerby;Abigail S. Hackam;Russell L. Margolis

  • Huntington's Chorea

    P Beighton;M R Hayden

  • Mutations in ABC1 in Tangier disease and familial high-density lipoprotein

    A Brooks-Wilson;Michel Marcil;Susanne M. Clee;Lin-Hua Zhang

Frequent Co-Authors

Roshni R. Singaraja
Roshni R. Singaraja Agency for Science, Technology and Research
Blair R. Leavitt
Blair R. Leavitt University of British Columbia
John J.P. Kastelein
John J.P. Kastelein University of Amsterdam
Rona K. Graham
Rona K. Graham Université de Sherbrooke
Lynn A. Raymond
Lynn A. Raymond University of British Columbia
Christopher A. Ross
Christopher A. Ross Johns Hopkins University School of Medicine
Marcy E. MacDonald
Marcy E. MacDonald Harvard University
John D. Brunzell
John D. Brunzell University of Washington
Jane S. Paulsen
Jane S. Paulsen University of Wisconsin–Madison
Donald W. Nicholson
Donald W. Nicholson MSD (United States)

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