D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge
Biology and Biochemistry
Canada
2022

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 130 Citations 63,220 559 World Ranking 170 National Ranking 4
Medicine D-index 122 Citations 50,219 530 World Ranking 1379 National Ranking 52
Best Scientists D-index 157 Citations 91,913 979 World Ranking 947 National Ranking 22

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Scientist Award

2022 - Research.com Biology and Biochemistry in Canada Leader Award

2011 - Canada Gairdner Wightman Award

2011 - Izaak Walton Killam Memorial Prize, Canada Council

1995 - Fellow of the Royal Society of Canada Academy of Science

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Enzyme

Huntingtin, Internal medicine, Huntington's disease, Huntingtin Protein and Cell biology are his primary areas of study. His Huntingtin research incorporates themes from Excitotoxicity, Molecular biology and Neurodegeneration. His studies deal with areas such as Endocrinology and Oncology as well as Internal medicine.

Michael R. Hayden focuses mostly in the field of Endocrinology, narrowing it down to matters related to ABCA1 and, in some cases, In vivo. The Huntington's disease study combines topics in areas such as Predictive testing, Genetics, Neuroscience and Trinucleotide repeat expansion. His studies in Cell biology integrate themes in fields like Apoptosis, Biochemistry, Huntingtin-interacting protein 1 and Caspase, Caspase 8.

His most cited work include:

  • Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency (1545 citations)
  • Loss of Huntingtin-Mediated BDNF Gene Transcription in Huntington's Disease (1102 citations)
  • Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. (868 citations)

What are the main themes of his work throughout his whole career to date?

Michael R. Hayden focuses on Internal medicine, Genetics, Huntingtin, Endocrinology and Huntington's disease. His research on Internal medicine frequently connects to adjacent areas such as Oncology. His Huntingtin research includes elements of Molecular biology, Neuroscience and Cell biology.

His research integrates issues of Caspase, Neurodegeneration and Palmitoylation in his study of Cell biology. His research on Endocrinology often connects related areas such as ABCA1. Disease and Pathology are the two main areas of interest in his Huntington's disease studies.

He most often published in these fields:

  • Internal medicine (28.78%)
  • Genetics (27.49%)
  • Huntingtin (24.60%)

What were the highlights of his more recent work (between 2014-2021)?

  • Huntingtin (24.60%)
  • Cell biology (14.24%)
  • Internal medicine (28.78%)

In recent papers he was focusing on the following fields of study:

Michael R. Hayden mostly deals with Huntingtin, Cell biology, Internal medicine, Pharmacology and Neuroscience. His biological study focuses on Huntingtin Protein. His research in Cell biology intersects with topics in Oxidative stress, Palmitoylation, Neurodegeneration, Caspase 6 and Programmed cell death.

His Internal medicine research incorporates themes from Endocrinology, Oncology, Bioinformatics, Gastroenterology and Placebo. His Neuroscience study integrates concerns from other disciplines, such as White matter and Huntington's disease, Disease. His Mutant study deals with Molecular biology intersecting with Gene silencing.

Between 2014 and 2021, his most popular works were:

  • Autophagy in Huntington disease and huntingtin in autophagy (185 citations)
  • A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer (125 citations)
  • A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer (125 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Enzyme

His main research concerns Huntingtin, Neuroscience, Internal medicine, Cell biology and Pharmacology. Particularly relevant to Huntingtin Protein is his body of work in Huntingtin. His biological study spans a wide range of topics, including Neuroinflammation, Disease, Monoamine neurotransmitter and Monoamine oxidase.

His Disease research integrates issues from Penetrance and Trinucleotide repeat expansion. His research investigates the link between Internal medicine and topics such as Endocrinology that cross with problems in Bioinformatics. Michael R. Hayden has researched Cell biology in several fields, including Glutamate receptor, Neurotrophic factors, Neurodegeneration, Caspase and Huntington's disease.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

A. Brooks-Wilson;M. Marcil;S. M. Clee;L.-H. Zhang.
Nature Genetics (1999)

1985 Citations

Loss of Huntingtin-Mediated BDNF Gene Transcription in Huntington's Disease

Chiara Zuccato;Andrea Ciammola;Dorotea Rigamonti;Blair R. Leavitt.
Science (2001)

1345 Citations

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis.

George Papanikolaou;Mark E Samuels;Erwin H Ludwig;Marcia L E MacDonald.
Nature Genetics (2004)

1149 Citations

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines

Alexander V. Panov;Claire-Anne Gutekunst;Blair R. Leavitt;Michael R. Hayden.
Nature Neuroscience (2002)

1106 Citations

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.

Chiara Zuccato;Marzia Tartari;Andrea Crotti;Donato Goffredo.
Nature Genetics (2003)

977 Citations

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes.

Jamal Nasir;Stan B Floresco;John R O'Kusky;Virginia M Diewert.
Cell (1995)

938 Citations

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

J.Graeme Hodgson;Nadia Agopyan;Claire-Anne Gutekunst;Blair R Leavitt.
Neuron (1999)

930 Citations

Aspirin for the Primary Prevention of Cardiovascular Events: A Summary of the Evidence for the U.S. Preventive Services Task Force

Michael Hayden;Michael Pignone;Christopher Phillips;Cynthia Mulrow.
Annals of Internal Medicine (2002)

891 Citations

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

Elizabeth J. Slow;Jeremy van Raamsdonk;Daniel Rogers;Sarah H. Coleman.
Human Molecular Genetics (2003)

806 Citations

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.

Shinji Hadano;Collette K. Hand;Hitoshi Osuga;Yoshiko Yanagisawa.
Nature Genetics (2001)

751 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Michael R. Hayden

Marcy E. MacDonald

Marcy E. MacDonald

Harvard University

Publications: 184

Sarah J. Tabrizi

Sarah J. Tabrizi

University College London

Publications: 183

Jane S. Paulsen

Jane S. Paulsen

University of Wisconsin–Madison

Publications: 174

James F. Gusella

James F. Gusella

Harvard University

Publications: 170

Christopher A. Ross

Christopher A. Ross

Johns Hopkins University School of Medicine

Publications: 163

Raymund A.C. Roos

Raymund A.C. Roos

Leiden University Medical Center

Publications: 130

Gillian P. Bates

Gillian P. Bates

University College London

Publications: 129

Xiao-Jiang Li

Xiao-Jiang Li

Jinan University

Publications: 119

John J.P. Kastelein

John J.P. Kastelein

University of Amsterdam

Publications: 105

Julie C. Stout

Julie C. Stout

Monash University

Publications: 97

Elena Cattaneo

Elena Cattaneo

University of Milan

Publications: 96

Frédéric Saudou

Frédéric Saudou

Grenoble Alpes University

Publications: 93

Daniel J. Rader

Daniel J. Rader

University of Pennsylvania

Publications: 91

Anthony J. Hannan

Anthony J. Hannan

Florey Institute of Neuroscience and Mental Health

Publications: 87

Robert A. Hegele

Robert A. Hegele

University of Western Ontario

Publications: 86

Sandrine Humbert

Sandrine Humbert

Grenoble Alpes University

Publications: 85

Trending Scientists

Herbert Ho-Ching Iu

Herbert Ho-Ching Iu

University of Western Australia

WT Tsai

WT Tsai

Arizona State University

Justin Wolf

Justin Wolf

University of Würzburg

Andrew D. Mesecar

Andrew D. Mesecar

Purdue University West Lafayette

Fujio Izumi

Fujio Izumi

Kyoto University

Lide Zhang

Lide Zhang

Chinese Academy of Sciences

Denise L. Breitburg

Denise L. Breitburg

Smithsonian Environmental Research Center

Stefano Pluchino

Stefano Pluchino

University of Cambridge

Andrew M. Borman

Andrew M. Borman

Public Health England

Deborah Yelon

Deborah Yelon

University of California, San Diego

Robert A. Nicholas

Robert A. Nicholas

University of North Carolina at Chapel Hill

Célia M. Manaia

Célia M. Manaia

Catholic University of Portugal

Iannis Dandouras

Iannis Dandouras

Federal University of Toulouse Midi-Pyrénées

Frank W. Weathers

Frank W. Weathers

Auburn University

Toshitaka Nabeshima

Toshitaka Nabeshima

Fujita Health University

Julie Barroso

Julie Barroso

Medical University of South Carolina

Something went wrong. Please try again later.