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Overview

Raymund A.C. Roos is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily focuses on genetic neurodegenerative diseases, with a notable emphasis on Huntington's disease. Their scientific contributions cover fields such as medicine and neuroscience, with specific subfields including cellular and molecular neuroscience, neurology, molecular biology, psychiatry and mental health, and radiology, nuclear medicine, and imaging.

Their work encompasses multiple topics related to neurological disorders and treatments, mitochondrial function and pathology, botulinum toxin and related neurological disorders, fibromyalgia and chronic fatigue syndrome research, Parkinson's disease mechanisms and treatments, and advanced neuroimaging techniques and applications.

Recent publications by Raymund A.C. Roos include:

  • Juvenile-Onset Huntington Disease Pathophysiology and Neurodevelopment: A Review, 2021, Movement Disorders
  • Disease Onset in Huntington's Disease: When Is the Conversion?, 2021, Movement Disorders Clinical Practice
  • Safety and efficacy of laquinimod for Huntington's disease (LEGATO-HD): a multicentre, randomised, double-blind, placebo-controlled, phase 2 study, 2024, The Lancet Neurology
  • Genetic topography and cortical cell loss in Huntington's disease link development and neurodegeneration, 2023, Brain
  • Composite UHDRS Correlates With Progression of Imaging Biomarkers in Huntington's Disease, 2021, Movement Disorders

Frequent co-authors in their publications include Susanne T. de Bot, Sarah J. Tabrizi, Alexandra Dürr, Kasper F. van der Zwaan, and Stephanie Feleus.

The venues where Raymund A.C. Roos has published most frequently are:

  • Journal of Huntington s Disease
  • Movement Disorders
  • Neurology
  • Movement Disorders Clinical Practice
  • Parkinsonism & Related Disorders

Best Publications

  • Huntington's disease: a clinical review

    Raymund A C Roos

  • Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data.

    Sarah J Tabrizi;Douglas R Langbehn;Blair R Leavitt;Raymund A C Roos

  • Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data

    Sarah J Tabrizi;Rachael I Scahill;Gail N Owen;Alexandra Durr

  • Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis

    Sarah J Tabrizi;Rachael I Scahill;Alexandra Durr;Raymund A C Roos

  • AMYLOID-BETA PROTEIN-PRECURSOR GENE AND HEREDITARY CEREBRAL-HEMORRHAGE WITH AMYLOIDOSIS (DUTCH)

    C. Van Broeckhoven;J. Haan;E. Bakker;J. A. Hardy

  • Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data

    Sarah J Tabrizi;Ralph Reilmann;Raymond A C Roos;Alexandra Durr

  • Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease

    Kirupa Sathasivam;Andreas Neueder;Theresa A. Gipson;Christian Landles

  • Neurofilament light protein in blood as a potential biomarker of neurodegeneration in Huntington's disease: a retrospective cohort analysis

    Lauren M Byrne;Filipe B. Rodrigues;Kaj Blennow;Kaj Blennow;Alexandra Durr

  • Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

    Davina J Hensman Moss;Antonio F Pardiñas;Douglas Langbehn;Kitty Lo

  • Influence of dopaminergic medication on automatic postural responses and balance impairment in Parkinson's disease

    Bastiaan R. Bloem;Bastiaan R. Bloem;Dennis J. Beckley;J. Gert van Dijk;Aeilko H. Zwinderman

  • Orexin loss in Huntington's disease

    Åsa Petersén;Joana Gil;Marion L.C. Maat-Schieman;Maria Björkqvist

  • Characterization and localization of the Huntington disease gene product

    André T. Hoogeveen;Rob Willemsen;Nicolle Meyer;Karien E.de Roolj

  • Prevalence of subjective dysphagia in community residents aged over 87.

    B R Bloem;A M Lagaay;W van Beek;J Haan

  • Pathophysiology of chorea and bradykinesia in Huntington's disease

    Alfredo Berardelli;Johannes Noth;Philip D. Thompson;Eduard L. E. M. Bollen

  • The Cerebral β‐Amyloid Angiopathies: Hereditary and Sporadic

    Sandy X. Zhang‐Nunes;Marion L. C. Maat‐Schieman;Sjoerd G. van Duinen;Raymund A. C. Roos

  • Atrophy of the Hypothalamic Lateral Tuberal Nucleus in Huntington's Disease

    H. P. H. Kremer;R. A. C. Roos;G. Dingjan;E. Marani

  • The MPTP model: versatile contributions to the treatment of idiopathic Parkinson's disease.

    B.R. Bloem;I. Irwin;O.J.S. Buruma;J. Haan

  • Falls and gait disturbances in Huntington's disease

    Yvette A.M. Grimbergen;Mirjam J. Knol;Bastiaan R. Bloem;Berry P.H. Kremer

  • Efficacy of community-based physiotherapy networks for patients with Parkinson's disease: a cluster-randomised trial

    Marten Munneke;Maarten J Nijkrake;Samyra Hj Keus;Samyra Hj Keus;Gert Kwakkel

  • Dementia in hereditary cerebral hemorrhage with amyloidosis-Dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles.

    Remco Natté;Marion L. C. Maat‐Schieman;Joost Haan;Marjolijn Bornebroek

Frequent Co-Authors

Sarah J. Tabrizi
Sarah J. Tabrizi University College London
Alexandra Durr
Alexandra Durr Sorbonne University
Blair R. Leavitt
Blair R. Leavitt University of British Columbia
Rachael I. Scahill
Rachael I. Scahill University College London
Julie C. Stout
Julie C. Stout Monash University
Douglas R. Langbehn
Douglas R. Langbehn University of Iowa
Ralf Reilmann
Ralf Reilmann University of Tübingen
Geraint Rees
Geraint Rees University College London
David Craufurd
David Craufurd University of Manchester
Jeffrey D. Long
Jeffrey D. Long University of Iowa

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