Douglas R. Langbehn

Best Publications

• Huntington disease: natural history, biomarkers and prospects for therapeutics

  Christopher A Ross;Elizabeth Hoppes Aylward;Edward J Wild;Douglas R Langbehn

  1113
  Citations

• Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data.

  Sarah J Tabrizi;Douglas R Langbehn;Blair R Leavitt;Raymund A C Roos

  1076
  Citations

• Detection of Huntington’s disease decades before diagnosis: The Predict HD study

  Jane Paulsen;Douglas R Langbehn;Julie C Stout;Elizabeth H Aylward

  969
  Citations

• Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data

  Sarah J Tabrizi;Rachael I Scahill;Gail N Owen;Alexandra Durr

  956
  Citations

• A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length.

  Douglas R. Langbehn;Ryan R. Brinkman;Daniel Falush;Jane S. Paulsen

  931
  Citations

• Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis

  Sarah J Tabrizi;Rachael I Scahill;Alexandra Durr;Raymund A C Roos

  686
  Citations

• Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data

  Sarah J Tabrizi;Ralph Reilmann;Raymond A C Roos;Alexandra Durr

  602
  Citations

• Psychiatric Symptoms in Huntington’s Disease before Diagnosis: The Predict-HD Study

  Kevin Duff;Jane S. Paulsen;Leigh J. Beglinger;Douglas R. Langbehn

  472
  Citations

• Neurocognitive Signs in Prodromal Huntington Disease

  Julie C. Stout;Jane S. Paulsen;Sarah Queller;Andrea C. Solomon

  445
  Citations

• CAG‐repeat length and the age of onset in Huntington disease (HD): A review and validation study of statistical approaches

  Douglas R Langbehn;Michael R Hayden;Jane S Paulsen

  433
  Citations

• Neurofilament light protein in blood as a potential biomarker of neurodegeneration in Huntington's disease: a retrospective cohort analysis

  Lauren M Byrne;Filipe B. Rodrigues;Kaj Blennow;Kaj Blennow;Alexandra Durr

  369
  Citations

• Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

  Davina J Hensman Moss;Antonio F Pardiñas;Douglas Langbehn;Kitty Lo

  347
  Citations

• Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington’s disease patients

  Edward J. Wild;Roberto Boggio;Douglas Langbehn;Nicola Robertson

  305
  Citations

• Longitudinal change in regional brain volumes in prodromal Huntington disease

  Elizabeth H. Aylward;Peggy C. Nopoulos;Christopher A. Ross;Douglas R. Langbehn

  298
  Citations

• fMRI Biomarker of Early Neuronal Dysfunction in Presymptomatic Huntington’s Disease

  Jane S. Paulsen;Janice L. Zimbelman;Janice L. Zimbelman;Sean C. Hinton;Douglas R. Langbehn

  296
  Citations

• Striatal and white matter predictors of estimated diagnosis for Huntington disease

  Jane S. Paulsen;Peggy C. Nopoulos;Elizabeth Aylward;Christopher A. Ross

  269
  Citations

• Associations of the serotonin transporter promoter polymorphism with aggressivity, attention deficit, and conduct disorder in an adoptee population.

  Remi J. Cadoret;Douglas Langbehn;Kristin Caspers;Edward P. Troughton

  247
  Citations

• Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's disease

  Shannon A Johnson;Shannon A Johnson;Julie C Stout;Julie C Stout;Andrea C Solomon;Douglas R Langbehn

  232
  Citations

• Clinical Correlates of Self-Mutilation Among Psychiatric Inpatients

  Douglas R. Langbehn;Bruce Pfohl

  214
  Citations

• Abnormal Brain Structure in Children With Isolated Clefts of the Lip or Palate

  Peg Nopoulos;Douglas R. Langbehn;John Canady;Vincent Magnotta

  213
  Citations