Edward J. Wild

Best Publications

• Huntington disease: natural history, biomarkers and prospects for therapeutics

  Christopher A Ross;Elizabeth Hoppes Aylward;Edward J Wild;Douglas R Langbehn

  1113
  Citations

• Huntington disease

  Unknown

  879
  Citations

• A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

  Maria Björkqvist;Edward J. Wild;Jenny Thiele;Aurelio Silvestroni

  750
  Citations

• Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis

  Bridel C;van Wieringen Wn;Zetterberg H;Tijms Bm

  706
  Citations

• Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities.

  Sarah J. Tabrizi;Michael D. Flower;Christopher A. Ross;Edward J. Wild

  475
  Citations

• Neurofilament light protein in blood as a potential biomarker of neurodegeneration in Huntington's disease: a retrospective cohort analysis

  Lauren M Byrne;Filipe B. Rodrigues;Kaj Blennow;Kaj Blennow;Alexandra Durr

  369
  Citations

• Potential disease-modifying therapies for Huntington's disease: lessons learned and future opportunities

  Unknown

  365
  Citations

• Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

  Davina J Hensman Moss;Antonio F Pardiñas;Douglas Langbehn;Kitty Lo

  347
  Citations

• Therapies targeting DNA and RNA in Huntington's disease.

  Edward J Wild;Sarah J Tabrizi

  310
  Citations

• Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington’s disease patients

  Edward J. Wild;Roberto Boggio;Douglas Langbehn;Nicola Robertson

  305
  Citations

• Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates.

  Annette Dalrymple;Edward J Wild;Richard Joubert;Kirupa Sathasivam

  278
  Citations

• Rapid eye movement sleep disturbances in Huntington disease.

  Isabelle Arnulf;Jørgen Nielsen;Ebba Lohmann;Johannes Schieffer

  271
  Citations

• Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY

  Michael Orth;O J Handley;C Schwenke

  266
  Citations

• C9orf72 expansions are the most common genetic cause of Huntington disease phenocopies

  Davina J. Hensman Moss;Mark Poulter;Jon Beck;Jason Hehir

  247
  Citations

• Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington’s disease

  Lauren M. Byrne;Filipe B. Rodrigues;Eileanor B. Johnson;Peter A. Wijeratne

  183
  Citations

• Mutant huntingtin fragmentation in immune cells tracks Huntington’s disease progression

  Andreas Weiss;Ulrike Träger;Edward J. Wild;Stephan Grueninger

  176
  Citations

• MSH3 modifies somatic instability and disease severity in Huntington's and myotonic dystrophy type 1.

  Michael Flower;Vilija Lomeikaite;Marc Ciosi;Sarah Cumming

  169
  Citations

• Biological and clinical characteristics of gene carriers far from predicted onset in the Huntington's disease Young Adult Study (HD-YAS): a cross-sectional analysis.

  Rachael I Scahill;Paul Zeun;Katherine Osborne-Crowley;Katherine Osborne-Crowley;Eileanoir B Johnson

  168
  Citations

• Analysis of potential transcriptomic biomarkers for Huntington's disease in peripheral blood

  Heike Runne;Alexandre Kuhn;Edward J. Wild;Wirahpati Pratyaksha

  168
  Citations

• Targets for future clinical trials in Huntington's disease: What's in the pipeline?

  Edward J. Wild;Sarah J. Tabrizi

  166
  Citations