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Michael Orth

Michael Orth

D-Index & Metrics

Neuroscience

D-Index
59
Citations
11544
World Ranking
4033
National Ranking
347

Overview

Michael Orth is affiliated with the University of Ulm in Germany. Their research primarily spans the fields of neuroscience as well as biochemistry, genetics, and molecular biology. Orth's work extends across subfields such as molecular biology, cellular and molecular neuroscience, neurology, cognitive neuroscience, and radiology, nuclear medicine, and imaging.

The scientist's research focuses on several key topics, including:

  • Genetic neurodegenerative diseases
  • Mitochondrial function and pathology
  • Muscle physiology and disorders
  • Transcranial magnetic stimulation studies
  • Functional brain connectivity studies
  • Neurological disorders and treatments
  • Fungal and yeast genetics research

Michael Orth has published in a range of scientific journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Huntington's Disease
  • The American Journal of Human Genetics
  • Clinical Neurophysiology
  • Science Translational Medicine

Among their recent publications are:

  • "Diagnostic contribution and therapeutic perspectives of transcranial magnetic stimulation in dementia" (2021, Clinical Neurophysiology)
  • "Huntington's Disease Pathogenesis: Two Sequential Components" (2021, Journal of Huntington's Disease)
  • "Genetic modifiers of Huntington disease differentially influence motor and cognitive domains" (2022, The American Journal of Human Genetics)
  • "Autism-associated SHANK3 mutations impair maturation of neuromuscular junctions and striated muscles" (2020, Science Translational Medicine)
  • "Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects" (2020, The American Journal of Human Genetics)

Orth frequently collaborates with other researchers. Notable co-authors include:

  • Jong-Min Lee
  • Peter Holmans
  • Jeffrey D. Long
  • James F. Gusella
  • Andreas Neueder

Best Publications

  • Identification of Genetic Factors that Modify Clinical Onset of Huntington’s Disease

    Jong-Min Lee;Vanessa C. Wheeler;Michael J. Chao;Jean Paul G. Vonsattel

  • CAG repeat not polyglutamine length determines timing of Huntington’s disease onset

    Jong-Min Lee;Kevin Correia;Jacob Loupe;Kyung-Hee Kim

  • Mitochondria and degenerative disorders.

    M. Orth;A.H.V. Schapira

  • Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

    Davina J Hensman Moss;Antonio F Pardiñas;Douglas Langbehn;Kitty Lo

  • Neuropsychiatric symptoms in a European Huntington's disease cohort (REGISTRY)

    Erik van Duijn;Erik van Duijn;David Craufurd;David Craufurd;Anna A M Hubers;Erik J Giltay

  • The cortical silent period: intrinsic variability and relation to the waveform of the transcranial magnetic stimulation pulse

    M Orth;J.C Rothwell

  • Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY

    Michael Orth;O J Handley;C Schwenke

  • The Gilles de la Tourette Syndrome–Quality of Life Scale (GTS-QOL): Development and validation

    A. E. Cavanna;A. Schrag;D. Morley;M. Orth

  • Expression of mutant α-synuclein causes increased susceptibility to dopamine toxicity

    Sarah J. Tabrizi;Michael Orth;J. Max Wilkinson;Jan-Willem Taanman

  • Mitochondrial involvement in Parkinson's disease.

    M Orth;A.H.V Schapira

  • The variability of intracortical inhibition and facilitation.

    M Orth;A.H Snijders;J.C Rothwell

  • Motor inhibition in patients with Gilles de la Tourette syndrome: functional activation patterns as revealed by EEG coherence

    Deborah J. Serrien;Michael Orth;Andrew H. Evans;Andrew J. Lees

  • An exploratory double-blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with Huntington's disease

    Sigurd D. Süssmuth;Salman Haider;G. Bernhard Landwehrmeyer;Ruth Farmer

  • Multispectral brain morphometry in Tourette syndrome persisting into adulthood.

    Bogdan Draganski;Davide Martino;Andrea E. Cavanna;Andrea E. Cavanna;Chloe Hutton

  • Structural changes in the somatosensory system correlate with tic severity in Gilles de la Tourette syndrome

    Götz Thomalla;Hartwig R. Siebner;Melanie Jonas;Tobias Bäumer

  • Consensus paper on short-interval intracortical inhibition and other transcranial magnetic stimulation intracortical paradigms in movement disorders.

    Alfredo Berardelli;Giovanni Abbruzzese;Robert Chen;Robert Chen;Michael Orth

  • The HTT CAG-Expansion Mutation Determines Age at Death but Not Disease Duration in Huntington Disease.

    Jae Whan Keum;Aram Shin;Tammy Gillis;Jayalakshmi Srinidhi Mysore

  • Excitability of motor cortex inhibitory circuits in tourette syndrome before and after single dose nicotine

    M. Orth;B. Amann;M. M. Robertson;J. C. Rothwell

  • Primary focal dystonia: evidence for distinct neuropsychiatric and personality profiles

    Rebekka Lencer;Susanne Steinlechner;Jessica Stahlberg;Hilka Rehling

  • Diagnostic contribution and therapeutic perspectives of transcranial magnetic stimulation in dementia.

    Vincenzo Di Lazzaro;Rita Bella;Alberto Benussi;Matteo Bologna

  • Abnormal Motor Cortex Excitability in Preclinical and Very Early Huntington's Disease

    Sven Schippling;Susanne A. Schneider;Khailash P. Bhatia;Alexander Münchau

  • Inhibitory and facilitatory connectivity from ventral premotor to primary motor cortex in healthy humans at rest--a bifocal TMS study.

    T. Bäumer;S. Schippling;S. Schippling;J. Kroeger;S. Zittel

  • Motor cortex excitability and comorbidity in Gilles de la Tourette syndrome

    Michael Orth;John Rothwell

  • Models of Parkinson's disease.

    Michael Orth;Sarah J. Tabrizi

  • Dissecting the Gilles de la Tourette spectrum: a factor analytic study on 639 patients

    Andrea E Cavanna;Hugo D Critchley;Michael Orth;Jeremy S Stern

Frequent Co-Authors

Marcy E. MacDonald
Marcy E. MacDonald Harvard University
Alexander Münchau
Alexander Münchau University of Lübeck
James F. Gusella
James F. Gusella Harvard University
Peter Holmans
Peter Holmans Cardiff University
Robert Christian Wolf
Robert Christian Wolf Heidelberg University
Lesley Jones
Lesley Jones Cardiff University
Jeffrey D. Long
Jeffrey D. Long University of Iowa
John C. Rothwell
John C. Rothwell University College London
Tobias Bäumer
Tobias Bäumer University of Lübeck
Carsten Saft
Carsten Saft Ruhr University Bochum

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