World's Best Scientists 2026 revealed!
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Best Scientists
2025

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Best Scientists

D-Index
194
Citations
165384
World Ranking
357
National Ranking
238

Medicine

D-Index
198
Citations
170152
World Ranking
196
National Ranking
131

Research.com Recognitions

  • 2025 - Research.com Best Scientists Award

Overview

Daniel J. Rader is affiliated with the University of Pennsylvania in the United States, where they conduct research primarily in the fields of medicine and biochemistry, genetics, and molecular biology. Their scholarly work spans multiple subfields including genetics, molecular biology, cardiology and cardiovascular medicine, surgery, and infectious diseases.

Their research covers a range of main topics, notably:

  • Genetic Associations and Epidemiology
  • Lipoproteins and Cardiovascular Health
  • Liver Disease Diagnosis and Treatment
  • Lipid Metabolism and Disorders
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies

Some of their most cited recent papers include:

  • "Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis" (2020, Nature Genetics)
  • "Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection" (2021, Cell)
  • "Whole-genome sequencing reveals host factors underlying critical COVID-19" (2022, Nature)
  • "Large-scale genome-wide association study of coronary artery disease in genetically diverse populations" (2022, Nature Medicine)
  • "Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity" (2021, Science)

The scientist frequently publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation
  • Nature Genetics
  • Journal of Clinical Lipidology
  • Journal of the American College of Cardiology

Collaborations are an important component of their work, with frequent co-authors including:

  • Scott M. Damrauer
  • Marylyn D. Ritchie
  • Anurag Verma
  • Renae Judy
  • Philip S. Tsao

Their publication record consists of over 700 works distributed mainly across medicine and genetics-oriented disciplines. The interdisciplinary nature of their research reflects a focus on genetic epidemiology, cardiovascular health, and increasingly on infectious disease mechanisms related to COVID-19.

Best Publications

  • Intensive versus moderate lipid lowering with statins after acute coronary syndromes.

    Christopher P. Cannon;Eugene Braunwald;Carolyn H. McCabe;Daniel J. Rader

  • Biological, clinical and population relevance of 95 loci for blood lipids

    Tanya M. Teslovich;Kiran Musunuru;Albert V. Smith;Andrew C. Edmondson

  • Discovery and refinement of loci associated with lipid levels

    Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta;Gina M. Peloso;Gina M. Peloso;Gina M. Peloso

  • Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes.

    Struan F. A. Grant;Gudmar Thorleifsson;Inga Reynisdottir;Rafil Benediktsson

  • A randomized trial of a low-carbohydrate diet for obesity.

    Gary D. Foster;Holly R. Wyatt;James O. Hill;Brian G. McGuckin

  • Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study

    Benjamin F. Voight;Benjamin F. Voight;Benjamin F. Voight;Gina M. Peloso;Gina M. Peloso;Marju Orho-Melander;Ruth Frikke-Schmidt

  • A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

    M Nikpay;A Goel;Won H-H.;L M Hall

  • Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis

    Amit V. Khera;Marina Cuchel;Margarita de la Llera-Moya;Amrith Rodrigues

  • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

    Heribert Schunkert;Inke R. König;Sekar Kathiresan;Muredach P. Reilly

  • Assessment of coronary artery disease by cardiac computed tomography : A scientific statement from the american heart association committee on cardiovascular imaging and intervention, council on cardiovascular radiology and intervention, and committee on cardiac imaging, council on clinical cardiology

    Matthew J. Budoff;Stephan Achenbach;Roger S. Blumenthal;J. Jeffrey Carr

  • A common variant on chromosome 9p21 affects the risk of myocardial infarction

    Anna Helgadottir;Gudmar Thorleifsson;Andrei Manolescu;Solveig Gretarsdottir

  • Large-scale association analysis identifies new risk loci for coronary artery disease

    Panos Deloukas;Stavroula Kanoni;Christina Willenborg;Martin Farrall

  • New insights into the regulation of HDL metabolism and reverse cholesterol transport.

    Gary F. Lewis;Daniel J. Rader

  • Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

    Amit V. Khera;Connor A. Emdin;Isabel Drake;Pradeep Natarajan

  • Resistin Is an Inflammatory Marker of Atherosclerosis in Humans

    Muredach P. Reilly;Michael Lehrke;Megan L. Wolfe;Anand K Rohatgi

  • From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

    Kiran Musunuru;Kiran Musunuru;Kiran Musunuru;Alanna Strong;Maria Frank-Kamenetsky;Noemi E. Lee

  • A variant in CDKAL1 influences insulin response and risk of type 2 diabetes.

    Valgerdur Steinthorsdottir;Gudmar Thorleifsson;Inga Reynisdottir;Rafn Benediktsson

  • Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

    Sekar Kathiresan;Benjamin F Voight;Shaun Purcell;Kiran Musunuru

  • A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

    Majid Nikpay;Anuj Goel;Hong-Hee Won;Leanne M. Hall

  • Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

    A.V. Khera;M. Cuchel;M. de la Llera-moya

Frequent Co-Authors

Muredach P. Reilly
Muredach P. Reilly Columbia University
Sekar Kathiresan
Sekar Kathiresan Harvard University
Danish Saleheen
Danish Saleheen Columbia University
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Themistocles L. Assimes
Themistocles L. Assimes Stanford University
Christopher J. O'Donnell
Christopher J. O'Donnell Harvard Medical School
John Danesh
John Danesh University of Cambridge
Gina M. Peloso
Gina M. Peloso Boston University
Jeffrey T. Billheimer
Jeffrey T. Billheimer University of Pennsylvania
Mingyao Li
Mingyao Li University of Pennsylvania

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