World's Best Scientists 2026 revealed!
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Best Scientists
2025
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Medicine
UK
2026

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Best Scientists

D-Index
166
Citations
163032
World Ranking
989
National Ranking
99

Medicine

D-Index
168
Citations
175974
World Ranking
549
National Ranking
66

Research.com Recognitions

  • 2026 - Research.com Medicine in United Kingdom Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in United Kingdom Leader Award

Overview

John Danesh is affiliated with the University of Cambridge in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with substantial contributions in Genetics, Molecular Biology, Cardiology and Cardiovascular Medicine, Physiology, and Public Health, Environmental and Occupational Health.

Their main research topics include Genetic Associations and Epidemiology, Bioinformatics and Genomic Networks, Telomeres, Telomerase, and Senescence, Nutritional Studies and Diet, Genomics and Rare Diseases, Epigenetics and DNA Methylation, and Lipid metabolism and disorders.

John Danesh has authored numerous papers, with recent notable publications as follows:

  • A genomic mutational constraint map using variation in 76,156 human genomes (2023, Nature)
  • Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis (2020, Nature Genetics)
  • Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases (2020, Nature Genetics)
  • Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals (2020, Nature Metabolism)
  • The Polygenic and Monogenic Basis of Blood Traits and Diseases (2020, Cell)

Their research has been published in a range of journals and venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Kidney International
  • Nature Communications
  • Nature Genetics
  • UNC Libraries

John Danesh collaborates regularly with several co-authors, including:

  • Adam S. Butterworth
  • Emanuele Di Angelantonio
  • Angela Wood
  • David J. Roberts
  • Willem H. Ouwehand

This profile reflects the scientist's diverse and multidisciplinary research activities, ranging from high-impact genetics studies to comprehensive epidemiological investigations and molecular biology inquiries within clinical and public health contexts.

Best Publications

  • UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age

    Cathie Sudlow;John Edward Gallacher;Naomi Allen;Valerie Beral

  • Analysis of protein-coding genetic variation in 60,706 humans

    Monkol Lek;Konrad J. Karczewski;Konrad J. Karczewski;Eric V. Minikel;Eric V. Minikel;Kaitlin E. Samocha

  • Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies

    N Sarwar;P Gao;Seshasai Srk.

  • C-Reactive Protein and Other Circulating Markers of Inflammation in the Prediction of Coronary Heart Disease

    John Danesh;Jeremy G Wheeler;Gideon M Hirschfield;Shinichi Eda

  • Major lipids, apolipoproteins, and risk of vascular disease

    E Di Angelantonio;N Sarwar;P Perry

  • Discovery and refinement of loci associated with lipid levels

    Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta;Gina M. Peloso;Gina M. Peloso;Gina M. Peloso

  • Serious mental disorder in 23 000 prisoners: a systematic review of 62 surveys

    Seena Fazel;John Danesh

  • Prevalence of serious mental disorder in 7000 refugees resettled in western countries: a systematic review.

    Mina Fazel;Jeremy Wheeler;John Danesh

  • Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies.

    John Danesh;Rory Collins;Paul Appleby;Richard Peto

  • C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis.

    S Kaptoge;E Di Angelantonio;G Lowe

  • Diabetes mellitus, fasting glucose, and risk of cause-specific death.

    Sreenivasa Rao Kondapally Seshasai;Stephen Kaptoge;Alexander Thompson;Emanuele Di Angelantonio

  • Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents

    Emanuele Di Angelantonio;Shilpa N Bhupathiraju;David Wormser;Pei Gao;Pei Gao

  • Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study

    Benjamin F. Voight;Benjamin F. Voight;Benjamin F. Voight;Gina M. Peloso;Gina M. Peloso;Marju Orho-Melander;Ruth Frikke-Schmidt

  • Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses

    John Danesh;Peter Whincup;Mary Walker;Lucy Lennon

  • A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

    M Nikpay;A Goel;Won H-H.;L M Hall

  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

    Andrew P Morris;Benjamin F Voight;Benjamin F Voight;Tanya M Teslovich;Teresa Ferreira

  • Clonal Hematopoiesis and risk of atherosclerotic cardiovascular disease

    Siddhartha Jaiswal;Pradeep Natarajan;Pradeep Natarajan;Alexander J. Silver;Christopher J. Gibson

  • Triglycerides and the Risk of Coronary Heart Disease 10 158 Incident Cases Among 262 525 Participants in 29 Western Prospective Studies

    Nadeem Sarwar;John Danesh;Gudny Eiriksdottir;Gunnar Sigurdsson

Frequent Co-Authors

Adam S. Butterworth
Adam S. Butterworth University of Cambridge
Danish Saleheen
Danish Saleheen Columbia University
Emanuele Di Angelantonio
Emanuele Di Angelantonio University of Cambridge
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Sekar Kathiresan
Sekar Kathiresan Harvard University
Panos Deloukas
Panos Deloukas Queen Mary University of London
Nicholas J. Wareham
Nicholas J. Wareham University of Cambridge
Markus Perola
Markus Perola Finnish Institute for Health and Welfare
Jaspal S. Kooner
Jaspal S. Kooner Imperial College London
John C. Chambers
John C. Chambers Guy's and St Thomas' NHS Foundation Trust

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