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Tadashi Kasahara

Tadashi Kasahara

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
16555
World Ranking
5721
National Ranking
369

Overview

Tadashi Kasahara is affiliated with Jichi Medical University in Japan. Their research work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with additional contributions to Medicine. Subfields of interest include Molecular Biology, Surgery, Immunology, Genetics, and Pulmonary and Respiratory Medicine.

The main topics explored in their research cover Inflammasome and immune disorders, Heme Oxygenase-1 and Carbon Monoxide, Nicotinic Acetylcholine Receptors Study, IL-33, ST2, and ILC Pathways, High Altitude and Hypoxia, Pulmonary Hypertension Research and Treatments, and Hydrogen's biological and therapeutic effects.

Recent papers authored or coauthored by Tadashi Kasahara include:

  • GSDME-Dependent Incomplete Pyroptosis Permits Selective IL-1α Release under Caspase-1 Inhibition, 2020, iScience
  • Glucose regulates hypoxia-induced NLRP3 inflammasome activation in macrophages, 2020, Journal of Cellular Physiology
  • NLRP3 Inflammasome Activation in Lung Vascular Endothelial Cells Contributes to Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury, 2020, The Journal of Immunology
  • GTS-21 Enhances Regulatory T Cell Development from T Cell Receptor-Activated Human CD4+ T Cells Exhibiting Varied Levels of CHRNA7 and CHRFAM7A Expression, 2023, International Journal of Molecular Sciences
  • GTS-21 Enhances Regulatory T Cell Development from T Cell Receptor-activated Human CD4+ T Cells Exhibiting Varied Levels of CHRNA7 and CHRFAM7A Expression, 2023, Preprints.org

Frequent coauthors working with Kasahara include:

  • Tadayoshi Karasawa
  • Sachiko Watanabe
  • Takanori Komada
  • Hiroaki Kimura
  • Ryo Kamata

Kasahara's work has been published in journals such as:

  • iScience
  • Journal of Cellular Physiology
  • The Journal of Immunology
  • International Journal of Molecular Sciences
  • Preprints.org

Best Publications

  • Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor.

    Y Yamaguchi;Y Hayashi;Y Sugama;Y Miura

  • Interleukin 2-mediated immune interferon (IFN-gamma) production by human T cells and T cell subsets.

    T Kasahara;J J Hooks;S F Dougherty;J J Oppenheim

  • Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression.

    N. Mukaida;M. Morita;Y. Ishikawa;N. Rice

  • Interleukin-2 enhances the depressed natural killer and cytomegalovirus-specific cytotoxic activities of lymphocytes from patients with the acquired immune deficiency syndrome.

    A H Rook;H Masur;H C Lane;W Frederick

  • Analysis of the survival of mature human eosinophils: interleukin-5 prevents apoptosis in mature human eosinophils.

    Yuji Yamaguchi;Toshio Suda;Shigeo Ohta;Kaoru Tominaga

  • Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60.

    Yoshiko Sonoda;Yaeko Matsumoto;Megumi Funakoshi;Daisuke Yamamoto

  • Capacity of human large granular lymphocytes (LGL) to produce multiple lymphokines: interleukin 2, interferon, and colony stimulating factor.

    T Kasahara;J Y Djeu;S F Dougherty;J J Oppenheim

  • FAK is the upstream signal protein of the phosphatidylinositol 3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line.

    Yoshiko Sonoda;Shiro Watanabe;Yaeko Matsumoto;Eriko Aizu-Yokota

  • Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin.

    Megumi Funakoshi-Tago;Kei Nakamura;Kenji Tago;Tadahiko Mashino

  • Human large granular lymphocytes are potent producers of interleukin-1

    Giuseppe Scala;Paola Allavena;Julie Y. Djeu;Tadashi Kasahara

  • Serum interleukin 6 levels become elevated in acute myocardial infarction.

    Uichi Ikeda;Fujio Ohkawa;Yoshitane Seino;Keiji Yamamoto

  • Glycyrrhizin and related compounds down-regulate production of inflammatory chemokines IL-8 and eotaxin 1 in a human lung fibroblast cell line.

    Sachiko Matsui;Hiroatsu Matsumoto;Yoshiko Sonoda;Kumi Ando

  • Elevation of amniotic fluid interleukin 6 (IL-6), IL-8 and granulocyte colony stimulating factor (G-CSF) in term and preterm parturition

    Shigeru Saito;Tadashi Kasahara;Yumiko Kato;Yuki Ishihara

  • IL-1 and TNF-alpha induction of IL-8 and monocyte chemotactic and activating factor (MCAF) mRNA expression in a human astrocytoma cell line.

    T. Kasahara;N. Mukaida;K. Yamashita;H. Yagisawa

  • Elevated interleukin-8 levels in the urine of patients with urinary tract infections.

    Y. C. Ko;N. Mukaida;S. Ishiyama;A. Tokue

  • Stimulation and priming of human neutrophils by interleukin-8: cooperation with tumor necrosis factor and colony-stimulating factors.

    Akira Yuo;Seiichi Kitagawa;Tadashi Kasahara;Kouji Matsushima

  • A sensitive enzyme-linked immunosorbent assay for human interleukin-8.

    Yue-chau Ko;Naofumi Mukaida;Alexander Panyutich;Nikolai N. Voitenok

  • TRAF6 is a critical signal transducer in IL-33 signaling pathway.

    Megumi Funakoshi-Tago;Kenji Tago;Morisada Hayakawa;Shin ichi Tominaga

  • Protection against lethal bacterial infection in mice by monocyte-chemotactic and -activating factor.

    Y. Nakano;T. Kasahara;N. Mukaida;Yue-Chau Ko

  • Induction of Monocyte Chemoattractant Protein-1 Synthesis in Human Monocytes During Transendothelial Migration In Vitro

    Masafumi Takahashi;Jun-Ichi Masuyama;Uichi Ikeda;Tadashi Kasahara

Frequent Co-Authors

Naofumi Mukaida
Naofumi Mukaida Kanazawa University
Masafumi Takahashi
Masafumi Takahashi Jichi Medical University
Kouji Matsushima
Kouji Matsushima Tokyo University of Science
Yasusada Miura
Yasusada Miura Jichi Medical University
Uichi Ikeda
Uichi Ikeda Shinshu University
Koichi Hirai
Koichi Hirai University of Tokyo
Kazuyuki Shimada
Kazuyuki Shimada Nagoya University
Koichiro Kawashima
Koichiro Kawashima Kitasato University
Toshio Suda
Toshio Suda National University of Singapore
Hidemi Misawa
Hidemi Misawa Keio University

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