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Masafumi Takahashi

Masafumi Takahashi

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
15332
World Ranking
7479
National Ranking
509

Overview

Masafumi Takahashi is affiliated with Jichi Medical University in Japan and has an extensive publication record primarily in medicine and biochemistry, genetics, and molecular biology. Their research spans numerous subfields including molecular biology, immunology, surgery, pulmonary and respiratory medicine, and cancer research.

Their work frequently appears in several scientific venues, with multiple publications in the Journal of Reproductive Immunology and the Journal of the American Society of Nephrology. Other common publication venues include the American Journal of Physiology-Heart and Circulatory Physiology, Nature Communications, and Archives of Toxicology.

Masafumi Takahashi's research has concentrated on topics such as inflammasome and immune disorders, ferroptosis and cancer prognosis, cancer with a focus on lipids and metabolism, heme oxygenase-1 and carbon monoxide, gout and hyperuricemia related to uric acid, RNA modifications in cancer, as well as drug transport and resistance mechanisms.

Frequent collaborations include work with Tadayoshi Karasawa, Takanori Komada, Naoya Yamada, Chintogtokh Baatarjav, and Takayoshi Matsumura.

Selected recent papers authored or co-authored by Masafumi Takahashi include:

  • NLRP3 inflammasome as a key driver of vascular disease, 2021, Cardiovascular Research
  • Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure, 2020, Cell Death and Disease
  • Iron overload as a risk factor for hepatic ischemia-reperfusion injury in liver transplantation: Potential role of ferroptosis, 2020, American Journal of Transplantation
  • Loop Between NLRP3 Inflammasome and Reactive Oxygen Species, 2021, Antioxidants and Redox Signaling
  • Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells, 2020, American Journal of Physiology-Heart and Circulatory Physiology

Best Publications

  • Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury

    Masanori Kawaguchi;Masafumi Takahashi;Takeki Hata;Yuichiro Kashima

  • c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1 (BMK1)

    Jun Ichi Abe;Masafumi Takahashi;Mari Ishida;Jiing Dwan Lee

  • Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure

    Naoya Yamada;Tadayoshi Karasawa;Hiroaki Kimura;Sachiko Watanabe

  • Cardiac Cell Sheet Transplantation Improves Damaged Heart Function via Superior Cell Survival in Comparison with Dissociated Cell Injection

    Hidekazu Sekine;Tatsuya Shimizu;Izumi Dobashi;Katsuhisa Matsuura

  • Mitogen-activated protein kinase (ERK1/2) activation by shear stress and adhesion in endothelial cells. Essential role for a herbimycin-sensitive kinase.

    M Takahashi;B C Berk

  • Role of NLRP3 Inflammasomes in Atherosclerosis.

    Tadayoshi Karasawa;Masafumi Takahashi

  • Clinicopathological features of genetically confirmed Danon disease

    K. Sugie;A. Yamamoto;K. Murayama;S. J. Oh

  • Green fluorescent protein-transgenic rat: a tool for organ transplantation research.

    Yoji Hakamata;Kazunori Tahara;Hiroo Uchida;Yasunaru Sakuma

  • Fluid shear stress stimulates big mitogen-activated protein kinase 1 (BMK1) activity in endothelial cells. Dependence on tyrosine kinases and intracellular calcium

    Chen Yan;Masafumi Takahashi;Masanori Okuda;Jiing-Dwan Lee

  • Mechanotransduction in Endothelial Cells: Temporal Signaling Events in Response to Shear Stress

    Masafumi Takahashi;Takafumi Ishida;Oren Traub;Marshall A. Corson

  • NLRP3 Inflammasome as a Novel Player in Myocardial Infarction

    Masafumi Takahashi

  • KRP-203, a Novel Synthetic Immunosuppressant, Prolongs Graft Survival and Attenuates Chronic Rejection in Rat Skin and Heart Allografts

    Hisashi Shimizu;Masafumi Takahashi;Takashi Kaneko;Takashi Murakami

  • Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src

    Takafumi Ishida;Mari Ishida;Mari Ishida;James Suero;Masafumi Takahashi

  • Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice.

    Fumitake Usui;Koumei Shirasuna;Hiroaki Kimura;Kazuki Tatsumi

  • Inflammasome Activation by Mitochondrial Oxidative Stress in Macrophages Leads to the Development of Angiotensin II–Induced Aortic Aneurysm

    Fumitake Usui;Koumei Shirasuna;Hiroaki Kimura;Kazuki Tatsumi

  • Cardiac Overexpression of Monocyte Chemoattractant Protein-1 in Transgenic Mice Prevents Cardiac Dysfunction and Remodeling After Myocardial Infarction

    Hajime Morimoto;Masafumi Takahashi;Atsushi Izawa;Hirohiko Ise

  • Guidelines for evaluating myocardial cell death.

    Paras K. Mishra;Adriana Adameova;Joseph A. Hill;Christopher P. Baines

  • Fluvastatin Inhibits Matrix Metalloproteinase-1 Expression in Human Vascular Endothelial Cells

    Uichi Ikeda;Masahisa Shimpo;Ruri Ohki;Hideko Inaba

  • Fluid shear stress-mediated signal transduction: how do endothelial cells transduce mechanical force into biological responses?

    Takafumi Ishida;Masafumi Takahashi;Marshall A. Corson;Bradford C. Berk

  • Development of new inbred transgenic strains of rats with LacZ or GFP.

    Hirokazu Inoue;Ichiro Ohsawa;Takashi Murakami;Atsushi Kimura

Frequent Co-Authors

Uichi Ikeda
Uichi Ikeda Shinshu University
Kazuyuki Shimada
Kazuyuki Shimada Nagoya University
Tadashi Kasahara
Tadashi Kasahara Jichi Medical University
Shun'ichiro Taniguchi
Shun'ichiro Taniguchi Shinshu University
Eiji Kobayashi
Eiji Kobayashi Keio University
Hiroaki Mizukami
Hiroaki Mizukami Jichi Medical University
Shin'ichi Takeda
Shin'ichi Takeda National Center of Neurology and Psychiatry
Keiya Ozawa
Keiya Ozawa Jichi Medical University
Yoichiro Iwakura
Yoichiro Iwakura Tokyo University of Science
Yoshiyuki Ohsugi
Yoshiyuki Ohsugi Roche (Switzerland)

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