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Medicine

D-Index
99
Citations
30501
World Ranking
8690
National Ranking
230

Overview

Shin'ichi Takeda is affiliated with the National Center of Neurology and Psychiatry in Japan. Their research activity focuses predominantly on biochemical, genetic, and molecular biology aspects within medicine, emphasizing molecular biology and genetics as key subfields. Takeda's work also intersects with surgery, physiology, and cardiology and cardiovascular medicine.

Their main research topics cover muscle physiology and disorders, tissue engineering and regenerative medicine, adipose tissue and metabolism, mesenchymal stem cell research, cardiomyopathy and myosin studies, neurogenetic and muscular disorders research, and RNA interference and gene delivery.

Takeda has contributed notably in several publication venues, frequently publishing in:

  • Stem Cell Research & Therapy
  • Scientific Reports
  • Research Square (Research Square)
  • Methods in molecular biology
  • Annals of Clinical and Translational Neurology

Their recent papers include the following:

  • Duchenne muscular dystrophy, 2021, Nature Reviews Disease Primers
  • Viltolarsen in Japanese Duchenne muscular dystrophy patients: A phase 1/2 study, 2020, Annals of Clinical and Translational Neurology
  • Pharmacological activation of SERCA ameliorates dystrophic phenotypes in dystrophin-deficient mdx mice, 2021, Human Molecular Genetics
  • Brain Dp140 alters glutamatergic transmission and social behaviour in the mdx52 mouse model of Duchenne muscular dystrophy, 2022, Progress in Neurobiology
  • Mutation-independent Proteomic Signatures of Pathological Progression in Murine Models of Duchenne Muscular Dystrophy, 2020, Molecular & Cellular Proteomics

Takeda has collaborated extensively with several frequent co-authors, including:

  • Yoshitsugu Aoki
  • Hirofumi Komaki
  • Yuko Miyagoe-Suzuki
  • Kenichiro Nogami
  • Yusuke Maruyama

Their research contributions span multiple studies related to Duchenne muscular dystrophy and associated molecular mechanisms, including work on gene therapies and protein function in muscular disorders. The frequent focus on molecular biology techniques aligns with their extensive publishing in methods and experimental biology journals.

Best Publications

  • Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle.

    Akiyoshi Uezumi;So Ichiro Fukada;Naoki Yamamoto;Shin'Ichi Takeda

  • Bone marrow stromal cells generate muscle cells and repair muscle degeneration.

    Mari Dezawa;Hiroto Ishikawa;Yutaka Itokazu;Tomoyuki Yoshihara

  • Duchenne muscular dystrophy.

    Dongsheng Duan;Nathalie Goemans;Shin'ichi Takeda;Eugenio Mercuri

  • Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle.

    Akiyoshi Uezumi;Takahito Ito;Daisuke Morikawa;Natsuko Shimizu

  • A mutation in the ceruloplasmin gene is associated with systemic hemosiderosis in humans.

    Kunihiro Yoshida;Kenichi Furihata;Shin'ichi Takeda;Akinori Nakamura

  • Molecular signature of quiescent satellite cells in adult skeletal muscle.

    So-ichiro Fukada;Akiyoshi Uezumi;Madoka Ikemoto;Satoru Masuda

  • Efficacy of systemic morpholino exon-skipping in Duchenne dystrophy dogs.

    Toshifumi Yokota;Qi‐long Lu;Terence Partridge;Masanori Kobayashi

  • Up-regulation of monocyte chemoattractant protein-1 in tubulointerstitial lesions of human diabetic nephropathy

    Takashi Wada;Kengo Furuichi;Norihiko Sakai;Yasunori Iwata

  • Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo

    Tomomi Oyama;Toshio Nagai;Hiroshi Wada;Atsuhiko Thomas Naito

  • Benefits of surgery for patients with pulmonary metastases from colorectal carcinoma

    Masayoshi Inoue;Mitsunori Ohta;Keiji Iuchi;Akihide Matsumura

  • Laminin α2 chain-null mutant mice by targeted disruption of the Lama2 gene: a new model of merosin (laminin 2)-deficient congenital muscular dystrophy

    Yuko Miyagoe;Kazunori Hanaoka;Ikuya Nonaka;Michiko Hayasaka

  • Activation of calcium signaling through Trpv1 by nNOS and peroxynitrite as a key trigger of skeletal muscle hypertrophy

    Naoki Ito;Urs T Ruegg;Akira Kudo;Yuko Miyagoe-Suzuki

  • Clinical Spectrum of Mediastinal Cysts

    Shin Ichi Takeda;Shinichiro Miyoshi;Masato Minami;Mitsunori Ohta

  • IgG4-associated idiopathic tubulointerstitial nephritis complicating autoimmune pancreatitis

    Shin-ichi Takeda;Joji Haratake;Takahiko Kasai;Chikako Takaeda

  • Skeletal muscle gene expression in space-flown rats.

    Takeshi Nikawa;Kazumi Ishidoh;Katsuya Hirasaka;Ibuki Ishihara

  • α1-Syntrophin Gene Disruption Results in the Absence of Neuronal-type Nitric-oxide Synthase at the Sarcolemma but Does Not Induce Muscle Degeneration

    Shuhei Kameya;Yuko Miyagoe;Ikuya Nonaka;Takaaki Ikemoto

  • Space shuttle flight (STS-90) enhances degradation of rat myosin heavy chain in association with activation of ubiquitin–proteasome pathway

    Madoka Ikemoto;Takeshi Nikawa;Shin′Ichi Takeda;Chiho Watanabe

  • Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice

    Masashi Nakatani;Yuka Takehara;Hiromu Sugino;Mitsuru Matsumoto

  • Dystrophin deficiency in canine X-linked muscular dystrophy in Japan (CXMDJ) alters myosin heavy chain expression profiles in the diaphragm more markedly than in the tibialis cranialis muscle.

    Katsutoshi Yuasa;Akinori Nakamura;Takao Hijikata;Shinichi Takeda

  • Primary germ cell tumors in the mediastinum: a 50-year experience at a single Japanese institution.

    Shin Ichi Takeda;Shinichiro Miyoshi;Mitsunori Ohta;Masato Minami

Frequent Co-Authors

Hikaru Matsuda
Hikaru Matsuda Osaka University
Ichizo Nishino
Ichizo Nishino Tokyo Medical University
Takashi Saito
Takashi Saito Nagoya City University
Meinoshin Okumura
Meinoshin Okumura Osaka University
Eric P. Hoffman
Eric P. Hoffman Binghamton University
Ikuya Nonaka
Ikuya Nonaka Tokyo Medical University
Naohiro Yonemoto
Naohiro Yonemoto University of Toyama
Masafumi Takahashi
Masafumi Takahashi Jichi Medical University
Eiji Kobayashi
Eiji Kobayashi Keio University
Tatsushi Toda
Tatsushi Toda University of Tokyo

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