What is he best known for?
The fields of study he is best known for:
Steve D. Wilton mainly focuses on Dystrophin, Molecular biology, Exon skipping, Duchenne muscular dystrophy and Genetics.
His Dystrophin research includes elements of Phenotype and RNA splicing.
His studies deal with areas such as Transcription factor, DUX4, Facioscapulohumeral muscular dystrophy, Small interfering RNA and RNA interference as well as Molecular biology.
His Exon skipping study deals with the bigger picture of Exon.
His work carried out in the field of Duchenne muscular dystrophy brings together such families of science as Eteplirsen, In vivo and Morpholino.
His work on Nemaline myopathy, Point mutation, Gene and Autosome is typically connected to Nemaline bodies as part of general Genetics study, connecting several disciplines of science.
His most cited work include:
- Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study. (690 citations)
- Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study (569 citations)
- Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology (468 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Exon, Dystrophin, Molecular biology, Duchenne muscular dystrophy and Exon skipping.
His Exon research integrates issues from RNA splicing, Morpholino and splice.
His research in Dystrophin intersects with topics in In vivo and Cell biology.
His work deals with themes such as Splice site mutation, Transfection, Gene mapping and Skeletal muscle, which intersect with Molecular biology.
His work in Duchenne muscular dystrophy covers topics such as Bioinformatics which are related to areas like Disease.
The various areas that he examines in his Exon skipping study include Nonsense mutation, Exon trapping and Gene duplication, Tandem exon duplication.
He most often published in these fields:
- Exon (54.95%)
- Dystrophin (39.56%)
- Molecular biology (37.64%)
What were the highlights of his more recent work (between 2017-2021)?
- Exon (54.95%)
- RNA splicing (31.32%)
- Exon skipping (37.64%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Exon, RNA splicing, Exon skipping, Molecular biology and splice.
His Exon research incorporates elements of Duchenne muscular dystrophy, Dystrophin and Morpholino.
His RNA splicing research is multidisciplinary, relying on both Cancer research, Mutation, Cystic fibrosis, Computational biology and Intron.
Steve D. Wilton combines subjects such as Glutamine and Spinocerebellar ataxia with his study of Exon skipping.
His Molecular biology research is multidisciplinary, incorporating elements of Transfection and Spliceosome.
The splice study combines topics in areas such as Collagen VI and Muscular dystrophy.
Between 2017 and 2021, his most popular works were:
- ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now? (89 citations)
- ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now? (89 citations)
- Precision Medicine through Antisense Oligonucleotide-Mediated Exon Skipping. (21 citations)
In his most recent research, the most cited papers focused on:
Steve D. Wilton focuses on Exon, RNA splicing, Cell biology, Alternative splicing and Morpholino.
Steve D. Wilton is interested in Exon skipping, which is a branch of Exon.
His studies in Exon skipping integrate themes in fields like Phosphorothioate Oligonucleotides, Duchenne muscular dystrophy and Spinocerebellar ataxia.
The study incorporates disciplines such as Cancer research, Computational biology and Oligonucleotide in addition to RNA splicing.
His research integrates issues of Glutamine, Transfection and Hedgehog signaling pathway in his study of Cell biology.
His Morpholino research is multidisciplinary, incorporating perspectives in Electroporation and Ataxin.
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