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Molecular Biology

D-Index
64
Citations
17014
World Ranking
1728
National Ranking
42

Overview

Steve D. Wilton is affiliated with the University of Western Australia in Australia. Their research spans multiple domains within biochemistry, genetics, molecular biology, and medicine, with a significant focus on molecular biology, genetics, neurology, surgery, and pulmonary and respiratory medicine.

The scientist's main areas of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, their notable subfields are:

  • Molecular Biology
  • Genetics
  • Neurology
  • Surgery
  • Pulmonary and Respiratory Medicine

The research topics covered by Steve D. Wilton include:

  • RNA Research and Splicing
  • Neurogenetic and Muscular Disorders Research
  • RNA Interference and Gene Delivery
  • Retinal Development and Disorders
  • RNA modifications and cancer
  • Muscle Physiology and Disorders
  • Advanced biosensing and bioanalysis techniques

Publications have appeared frequently in these venues:

  • International Journal of Molecular Sciences
  • Frontiers in Genetics
  • Scientific Reports
  • Stem Cell Research
  • bioRxiv (Cold Spring Harbor Laboratory)

Steve D. Wilton has collaborated extensively with several researchers, including:

  • Sue Fletcher
  • May T. Aung-Htut
  • Dunhui Li
  • Kristin A. Ham
  • Craig S. McIntosh

Recent papers authored or co-authored by Steve D. Wilton include:

  • Neurodegenerative diseases: a hotbed for splicing defects and the potential therapies (2021, Translational Neurodegeneration)
  • NEAT1 polyA-modulating antisense oligonucleotides reveal opposing functions for both long non-coding RNA isoforms in neuroblastoma (2020, Cellular and Molecular Life Sciences)
  • Structural Variants May Be a Source of Missing Heritability in sALS (2020, Frontiers in Neuroscience)
  • Progress in the molecular pathogenesis and nucleic acid therapeutics for Parkinson's disease in the precision medicine era (2020, Medicinal Research Reviews)
  • Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+10 kb C-to-T splicing mutation (2021, Journal of Cystic Fibrosis)

Best Publications

  • Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study.

    Sebahattin Cirak;Virginia Arechavala-Gomeza;Michela Guglieri;Lucy Feng

  • Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study

    Maria Kinali;Maria Kinali;Virginia Arechavala-Gomeza;Lucy Feng;Sebahattin Cirak

  • Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease'

    Peter Davies;Judith Resnick;Burton Resnick;Sid Gilman

  • Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

    Julia Alter;Fang Lou;Adam Rabinowitz;HaiFang Yin

  • Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements

    Lucy W. Barrett;Sue Fletcher;Steve D. Wilton

  • ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now?

    Rita Mejzini;Loren Louise Flynn;Loren Louise Flynn;Ianthe Leigh Pitout;Ianthe Leigh Pitout;Sue Fletcher;Sue Fletcher

  • Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse.

    Qi Long Lu;Christopher J Mann;Fang Lou;George Bou-Gharios

  • Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse

    Christopher J. Mann;Kaite Honeyman;Andy J. Cheng;Tina Ly

  • A mutation in the alpha tropomyosin gene TPM3 associated with autosomal dominant nemaline myopathy.

    Laing Ng;Wilton Sd;Akkari Pa;Akkari Pa;Dorosz S

  • Antisense oligonucleotide-induced exon skipping across the human dystrophin gene transcript.

    Steve D Wilton;Abbie M Fall;Penny L Harding;Graham McClorey

  • Detection and Identification of Multiple Mycobacterial Pathogens by DNA Amplification in a Single Tube

    Steve Wilton;Debby Cousins

  • Specific removal of the nonsense mutation from the mdx dystrophin mRNA using antisense oligonucleotides

    Stephen D Wilton;Frances Lloyd;Kylie Carville;Sue Fletcher

  • Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD

    Graham Mcclorey;H.M. Moulton;P.L. Iversen;Susan Fletcher

  • A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse

    Paul N. Porensky;Chalermchai Mitrpant;Vicki L. McGovern;Adam K. Bevan

  • Massive idiosyncratic exon skipping corrects the nonsense mutation in dystrophic mouse muscle and produces functional revertant fibers by clonal expansion.

    Q.L. Lu;G.E. Morris;Steve Wilton;T. Ly

  • Morpholino antisense oligonucleotide induced dystrophin exon 23 skipping in mdx mouse muscle

    Bianca L. Gebski;Chrisopher J. Mann;Susan Fletcher;Stephen D. Wilton

  • Dystrophin expression in the mdx mouse after localised and systemic administration of a morpholino antisense oligonucleotide

    Susan Fletcher;Kaite Honeyman;Abbie M. Fall;Penny L. Harding

  • Use of polymerase chain reaction for rapid diagnosis of tuberculosis.

    D.V. Cousins;Steve Wilton;B.R. Francis;B.L. Gow

  • Improved antisense oligonucleotide induced exon skipping in the mdx mouse model of muscular dystrophy.

    Christopher J. Mann;Kaite Honeyman;Graham McClorey;Sue Fletcher

  • Comparative analysis of antisense oligonucleotide sequences for targeted skipping of exon 51 during dystrophin pre-mRNA splicing in human muscle

    V. Arechavala-Gomeza;I.R. Graham;L.J. Popplewell;Abbie Adams

Frequent Co-Authors

Sue Fletcher
Sue Fletcher Murdoch University
Nigel G. Laing
Nigel G. Laing University of Western Australia
Francesco Muntoni
Francesco Muntoni University College London
Frank L. Mastaglia
Frank L. Mastaglia University of Western Australia
Arthur H.M. Burghes
Arthur H.M. Burghes The Ohio State University
Patrick L. Iversen
Patrick L. Iversen Oregon State University
Kevin M. Flanigan
Kevin M. Flanigan The Ohio State University
Daniel G. MacArthur
Daniel G. MacArthur Garvan Institute of Medical Research
John E.J. Rasko
John E.J. Rasko Centenary Institute of Cancer Medicine and Cell Biology
Alessandra Ferlini
Alessandra Ferlini University of Ferrara

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