His primary areas of investigation include Morpholino, Molecular biology, Oligonucleotide, Biochemistry and Pharmacology. Patrick L. Iversen interconnects Translation, RNA splicing and Viral replication in the investigation of issues within Morpholino. The various areas that Patrick L. Iversen examines in his Molecular biology study include Cell growth, RNA, Duchenne muscular dystrophy, Dystrophin and Messenger RNA.
His research integrates issues of Nucleic acid, Covalent bond, Molecule, Stereochemistry and splice in his study of Oligonucleotide. His Pharmacology research is multidisciplinary, incorporating perspectives in Myelogenous, Systemic administration, Refractory and Biodistribution. His work carried out in the field of Peptide brings together such families of science as Cell and Oligomer.
His primary scientific interests are in Molecular biology, Morpholino, Oligonucleotide, Virology and Biochemistry. Patrick L. Iversen has included themes like RNA, Messenger RNA, Gene expression, Gene and In vivo in his Molecular biology study. The study incorporates disciplines such as In vitro and Microbiology in addition to In vivo.
Patrick L. Iversen combines subjects such as Cancer research, Oligomer, RNA splicing, Pharmacology and Peptide with his study of Morpholino. His research in Cancer research intersects with topics in Cancer, Stem cell and Immunology. His studies in Oligonucleotide integrate themes in fields like Cell, Nucleic acid and Stereochemistry.
Patrick L. Iversen mainly investigates Morpholino, Virology, Molecular biology, Cell biology and Gene. His research on Morpholino concerns the broader Biochemistry. His Virology study incorporates themes from Arenavirus and Severe acute respiratory syndrome coronavirus 2.
His research in Molecular biology intersects with topics in Complementation, Mutant, Escherichia coli, Peptide and In vivo. As a part of the same scientific study, Patrick L. Iversen usually deals with the Peptide, concentrating on Microbiology and frequently concerns with Acinetobacter lwoffii. His Cell biology study also includes
Virology, Morpholino, Marburgvirus, Ebola virus and Marburg virus are his primary areas of study. Patrick L. Iversen does research in Virology, focusing on Virus specifically. His Morpholino research includes elements of Oligomer, Function, Molecular biology, Arginine and Regulatory T cell.
His work deals with themes such as Cerebellum, Transport protein, Blood–brain barrier, Mutation and Ataxia-telangiectasia, which intersect with Molecular biology. The Marburgvirus study combines topics in areas such as Marburg virus disease, Pharmacokinetics and Ebola virus and Marburg virus. His Ebola virus and Marburg virus research incorporates themes from Gene, Pharmacology and Cell-penetrating peptide.
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Oligonucleotides containing 5-fluorouracil
William H. Gmeiner;Patrick L. Iversen.
Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice.
Natee Jearawiriyapaisarn;Hong M Moulton;Brian Buckley;Jennifer Roberts.
Molecular Therapy (2008)
Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer
Bo Wu;Hong M. Moulton;Patrick L. Iversen;Jiangang Jiang.
Proceedings of the National Academy of Sciences of the United States of America (2008)
Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD
Graham Mcclorey;H.M. Moulton;P.L. Iversen;Susan Fletcher.
Gene Therapy (2006)
Cellular Uptake of Antisense Morpholino Oligomers Conjugated to Arginine-Rich Peptides
Hong M Moulton;Michelle H Nelson;Susie A Hatlevig;Muralimohan T Reddy.
Bioconjugate Chemistry (2004)
Advanced antisense therapies for postexposure protection against lethal filovirus infections
Travis K Warren;Kelly L Warfield;Jay Wells;Dana L Swenson.
Nature Medicine (2010)
Suppression of Philadelphia1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotide
Tomasz Skorski;Malgorzata Nieborowska-Skorska;Nicholas C. Nicolaides;Cezary Szczylik.
Proceedings of the National Academy of Sciences of the United States of America (1994)
Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents.
Saïd Abes;Hong M. Moulton;Philippe Clair;Paul Prevot.
Journal of Controlled Release (2006)
Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells.
Derek S. Youngblood;Susie A. Hatlevig;Jed N. Hassinger;Patrick L. Iversen.
Bioconjugate Chemistry (2007)
Systemic Administration of a Phosphorothioate Oligonucleotide with a Sequence Complementary to p53 for Acute Myelogenous Leukemia and Myelodysplastic Syndrome: Initial Results of a Phase I Trial
Eliel Bayever;Patrick L. Iversen;Michael R. Bishop;J. Graham Sharp.
Antisense research and development (1993)
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