D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 80 Citations 16,723 315 World Ranking 2634 National Ranking 1410

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary areas of investigation include Morpholino, Molecular biology, Oligonucleotide, Biochemistry and Pharmacology. Patrick L. Iversen interconnects Translation, RNA splicing and Viral replication in the investigation of issues within Morpholino. The various areas that Patrick L. Iversen examines in his Molecular biology study include Cell growth, RNA, Duchenne muscular dystrophy, Dystrophin and Messenger RNA.

His research integrates issues of Nucleic acid, Covalent bond, Molecule, Stereochemistry and splice in his study of Oligonucleotide. His Pharmacology research is multidisciplinary, incorporating perspectives in Myelogenous, Systemic administration, Refractory and Biodistribution. His work carried out in the field of Peptide brings together such families of science as Cell and Oligomer.

His most cited work include:

  • Oligonucleotides containing 5-fluorouracil (520 citations)
  • Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice. (232 citations)
  • Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer (218 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Molecular biology, Morpholino, Oligonucleotide, Virology and Biochemistry. Patrick L. Iversen has included themes like RNA, Messenger RNA, Gene expression, Gene and In vivo in his Molecular biology study. The study incorporates disciplines such as In vitro and Microbiology in addition to In vivo.

Patrick L. Iversen combines subjects such as Cancer research, Oligomer, RNA splicing, Pharmacology and Peptide with his study of Morpholino. His research in Cancer research intersects with topics in Cancer, Stem cell and Immunology. His studies in Oligonucleotide integrate themes in fields like Cell, Nucleic acid and Stereochemistry.

He most often published in these fields:

  • Molecular biology (36.75%)
  • Morpholino (27.07%)
  • Oligonucleotide (21.08%)

What were the highlights of his more recent work (between 2010-2021)?

  • Morpholino (27.07%)
  • Virology (16.52%)
  • Molecular biology (36.75%)

In recent papers he was focusing on the following fields of study:

Patrick L. Iversen mainly investigates Morpholino, Virology, Molecular biology, Cell biology and Gene. His research on Morpholino concerns the broader Biochemistry. His Virology study incorporates themes from Arenavirus and Severe acute respiratory syndrome coronavirus 2.

His research in Molecular biology intersects with topics in Complementation, Mutant, Escherichia coli, Peptide and In vivo. As a part of the same scientific study, Patrick L. Iversen usually deals with the Peptide, concentrating on Microbiology and frequently concerns with Acinetobacter lwoffii. His Cell biology study also includes

  • Bioinformatics and Cell most often made with reference to Interleukin,
  • Nuclear receptor that connect with fields like Glucocorticoid receptor, Cytochrome P450 and Metabolism,
  • Antisense oligonucleotides which intersects with area such as Selective modulation, Endocrinology and Internal medicine.

Between 2010 and 2021, his most popular works were:

  • Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections. (81 citations)
  • Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum (80 citations)
  • Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy (61 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Virology, Morpholino, Marburgvirus, Ebola virus and Marburg virus are his primary areas of study. Patrick L. Iversen does research in Virology, focusing on Virus specifically. His Morpholino research includes elements of Oligomer, Function, Molecular biology, Arginine and Regulatory T cell.

His work deals with themes such as Cerebellum, Transport protein, Blood–brain barrier, Mutation and Ataxia-telangiectasia, which intersect with Molecular biology. The Marburgvirus study combines topics in areas such as Marburg virus disease, Pharmacokinetics and Ebola virus and Marburg virus. His Ebola virus and Marburg virus research incorporates themes from Gene, Pharmacology and Cell-penetrating peptide.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Oligonucleotides containing 5-fluorouracil

William H. Gmeiner;Patrick L. Iversen.
(1993)

520 Citations

Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice.

Natee Jearawiriyapaisarn;Hong M Moulton;Brian Buckley;Jennifer Roberts.
Molecular Therapy (2008)

370 Citations

Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

Bo Wu;Hong M. Moulton;Patrick L. Iversen;Jiangang Jiang.
Proceedings of the National Academy of Sciences of the United States of America (2008)

328 Citations

Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD

Graham Mcclorey;H.M. Moulton;P.L. Iversen;Susan Fletcher.
Gene Therapy (2006)

321 Citations

Cellular Uptake of Antisense Morpholino Oligomers Conjugated to Arginine-Rich Peptides

Hong M Moulton;Michelle H Nelson;Susie A Hatlevig;Muralimohan T Reddy.
Bioconjugate Chemistry (2004)

300 Citations

Advanced antisense therapies for postexposure protection against lethal filovirus infections

Travis K Warren;Kelly L Warfield;Jay Wells;Dana L Swenson.
Nature Medicine (2010)

257 Citations

Suppression of Philadelphia1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotide

Tomasz Skorski;Malgorzata Nieborowska-Skorska;Nicholas C. Nicolaides;Cezary Szczylik.
Proceedings of the National Academy of Sciences of the United States of America (1994)

247 Citations

Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents.

Saïd Abes;Hong M. Moulton;Philippe Clair;Paul Prevot.
Journal of Controlled Release (2006)

246 Citations

Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells.

Derek S. Youngblood;Susie A. Hatlevig;Jed N. Hassinger;Patrick L. Iversen.
Bioconjugate Chemistry (2007)

230 Citations

Systemic Administration of a Phosphorothioate Oligonucleotide with a Sequence Complementary to p53 for Acute Myelogenous Leukemia and Myelodysplastic Syndrome: Initial Results of a Phase I Trial

Eliel Bayever;Patrick L. Iversen;Michael R. Bishop;J. Graham Sharp.
Antisense research and development (1993)

226 Citations

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