His scientific interests lie mostly in Oligonucleotide, Molecular biology, Stereochemistry, DNA and Phosphodiester bond. His Oligonucleotide study results in a more complete grasp of Biochemistry. Gerald Zon has included themes like Gene expression, Gene, Transfection, Sense and Viral replication in his Molecular biology study.
The concepts of his Stereochemistry study are interwoven with issues in Meso-tetrakisporphyrin, Medicinal chemistry and Peptide. His DNA research includes themes of Nucleic acid, Phase, Triethylammonium acetate, RNA and Enzyme. His Phosphodiester bond study combines topics in areas such as Depolymerization, Cytoplasm, Base and Polysaccharide.
Stereochemistry, Oligonucleotide, Molecular biology, Biochemistry and DNA are his primary areas of study. His studies deal with areas such as Adduct and Cyclophosphamide as well as Stereochemistry. As a part of the same scientific study, he usually deals with the Oligonucleotide, concentrating on Phosphodiester bond and frequently concerns with Phosphorothioate Oligonucleotides.
In his study, Cell growth and Sense is strongly linked to Cell culture, which falls under the umbrella field of Molecular biology. Many of his studies on DNA apply to RNA as well. Gerald Zon combines subjects such as Crystallography and Proton NMR with his study of Nuclear magnetic resonance spectroscopy.
His main research concerns Molecular biology, Biochemistry, Nucleic acid, In vivo and Bisulfite sequencing. His Molecular biology research is multidisciplinary, incorporating elements of Cell culture, Computational biology, DNA and DNA methylation. His Crystallography research extends to the thematically linked field of Biochemistry.
The various areas that he examines in his Nucleic acid study include Nucleic acid sequence, DNA ligase, Organic chemistry and Ligation. The study incorporates disciplines such as In vitro, Small interfering RNA, Immunology, RNA interference and Toxicity in addition to In vivo. His work on Deoxyribonucleotide as part of general Oligonucleotide research is often related to Streptavidin, thus linking different fields of science.
His primary scientific interests are in Molecular biology, In vivo, Cancer research, Chronic myelogenous leukemia and RNA interference. His Molecular biology study incorporates themes from genomic DNA, Bisulfite sequencing, Cell culture, Oncogene and Sense. His In vivo research includes elements of In vitro and Genetic enhancement.
His biological study spans a wide range of topics, including Confocal microscopy, Cell biology, Liposome and Gene. His Chronic myelogenous leukemia research is multidisciplinary, relying on both breakpoint cluster region, K562 cells and ABL. His RNA interference study combines topics from a wide range of disciplines, such as Transcription and Transfection, Small interfering RNA.
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Phosphorothioate analogs of oligodeoxynucleotides: inhibitors of replication and cytopathic effects of human immunodeficiency virus.
Makoto Matsukura;Kazuo Shinozuka;Gerald Zon;Hiroaki Mitsuya.
Proceedings of the National Academy of Sciences of the United States of America (1987)
Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells
Tomasz Skorski;Palanisamy Kanakaraj;Margaret Nieborowska-Skorska;Mariusz Z. Ratajczak.
Oligonucleotide Analogues as Potential Chemotherapeutic Agents
Pharmaceutical Research (1988)
Automated solid-phase synthesis, separation, and stereochemistry of phosphorothioate analogs of oligodeoxyribonucleotides
Wojciech J. Stec;Gerald Zon;William Egan.
Journal of the American Chemical Society (1984)
Automated system for polynucleotide synthesis and purification
William A. Andrus;Christie D. Mccollum;Gerald Zon.
Assignment of the 31P and 1H resonances in oligonucleotides by two-dimensional NMR spectroscopy
Vladimir Sklenár̆;Hirotsugu Miyashiro;Gerald Zon;H. Todd Miles.
FEBS Letters (1986)
Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells.
Makoto Matsukura;Gerald Zon;Kazuo Shinozuka;Marjorie Robert-Guroff.
Proceedings of the National Academy of Sciences of the United States of America (1989)
Use of hexachlorodisilane as a reducing agent. Stereospecific deoxygenation of acyclic phosphine oxides
Klaus Naumann;Gerald Zon;Kurt Mislow.
Journal of the American Chemical Society (1969)
In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides
Mariusz Z. Ratajczak;Jeffrey A. Kant;Selina M. Luger;Nobuko Hijiya.
Proceedings of the National Academy of Sciences of the United States of America (1992)
Comparative inhibition of chloramphenicol acetyltransferase gene expression by antisense oligonucleotide analogues having alkyl phosphotriester, methylphosphonate and phosphorothioate linkages
Carol Marcus-Sekura;Amy M. Woerner;Kazuo Shinozuka;Gerald Zon;Gerald Zon.
Nucleic Acids Research (1987)
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