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Chemistry

D-Index
64
Citations
12331
World Ranking
8169
National Ranking
2356

Research.com Recognitions

  • 1994 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1975 - Fellow of Alfred P. Sloan Foundation

Overview

David G. Gorenstein is affiliated with The University of Texas Health Science Center at Houston in the United States. Their research focuses on multiple areas within biochemistry, genetics, molecular biology, and medicine.

The main fields of study in which they have published include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their subfields cover several specialized topics, such as:

  • Molecular Biology
  • Immunology and Allergy
  • Oncology
  • Cancer Research
  • Radiology, Nuclear Medicine and Imaging

The main topics addressed in their work include:

  • Angiogenesis and VEGF in Cancer
  • Cell Adhesion Molecules Research
  • Chemokine receptors and signaling
  • Cancer-related molecular mechanisms research
  • Chemical Synthesis and Analysis
  • Advanced biosensing and bioanalysis techniques
  • Monoclonal and Polyclonal Antibodies Research

Frequent co-authors in their publications are:

  • G.L. Lokesh
  • David E. Volk
  • Takemi Tanaka
  • Hongyu Wang
  • Yoshihiro Morita

David G. Gorenstein has published in several scientific journals, mainly including:

  • Cancers
  • JCI Insight
  • Bioengineering

Among their recent research articles are:

  • Functional Blockade of E-Selectin in Tumor-Associated Vessels Enhances Anti-Tumor Effect of Doxorubicin in Breast Cancer (2020, Cancers)
  • Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy (2021, JCI Insight)
  • Development and Characterization of CD44-Targeted X-Aptamers with Enhanced Binding Affinity for Cancer Therapeutics (2025, Bioengineering)

David G. Gorenstein has received professional recognition including:

  • Fellow of the American Association for the Advancement of Science (AAAS), 1994
  • Fellow of Alfred P. Sloan Foundation, 1975

Best Publications

  • Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice

    Javier Martinez-Botas;John B. Anderson;Darin Tessier;Alexandre Lapillonne

  • Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol.

    Susan Wang;Robert J. Lee;Greg Cauchon;David G. Gorenstein

  • Dependence of phosphorus-31 chemical shifts on oxygen-phosphorus-oxygen bond angles in phosphate esters

    David G. Gorenstein

  • Aptamers and the next generation of diagnostic reagents

    Varatharasa Thiviyanathan;David G. Gorenstein

  • Conformation and Dynamics of DNA and Protein-DNA Complexes by 31P NMR

    David G. Gorenstein

  • Stereoelectronic effects in biomolecules

    David G. Gorenstein

  • Non-biological aspects of phosphorus-31 NMR spectroscopy

    David G. Gorenstein

  • 31P chemical shifts in phosphate diester monoanions. Bond angle and torsional angle effects

    David G. Gorenstein;Debojyoti Kar

  • Effect of distortions in the deoxyribose phosphate backbone conformation of duplex oligodeoxyribonucleotide dodecamers containing GT, GG, GA, AC, and GU base-pair mismatches on 31P NMR spectra.

    Vikram A. Roongta;Claude R. Jones;David G. Gorenstein

  • On the evaluation of interproton distances for three-dimensional structure determination by NMR using a relaxation rate matrix analysis

    Carol Beth Post;Robert P. Meadows;David G. Gorenstein

  • Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine.

    Lenard M. Lichtenberger;Yong Zhou;Vasanthi Jayaraman;Janice R. Doyen

  • Nucleotide Conformational Analysis by 31P Nuclear Magnetic Resonance Spectroscopy

    David G. Gorenstein

  • Temperature dependence of the 31P chemical shifts of nucleic acids. A prode of phosphate ester torsional conformations.

    David G. Gorenstein;John B. Findlay;Robert K. Momii;Bruce A. Luxon

  • Novel Combinatorial Selection of Phosphorothioate Oligonucleotide Aptamers

    David J. King;Daniel A. Ventura;and Allan R. Brasier;David G. Gorenstein

  • E-selectin-targeted porous silicon particle for nanoparticle delivery to the bone marrow

    Aman P. Mann;Takemi Tanaka;Anoma Somasunderam;Xuewu Liu

  • Assignments of 31P NMR resonances in oligodeoxyribonucleotides: origin of sequence-specific variations in the deoxyribose phosphate backbone conformation and the 31P chemical shifts of double-helical nucleic acids.

    David G. Gorenstein;Stephen A. Schroeder;Josepha M. Fu;James T. Metz

  • A minor groove binding track in reverse transcriptase.

    Katarzyna Bebenek;William A. Beard;William A. Beard;Thomas A. Darden;Leping Li

  • A generalized gauche NMR effect in carbon-13, fluorine-19, and phosphorus-31 chemical shifts and directly bonded coupling constants. Torsional angle and bond angle effects

    David G. Gorenstein

  • Apparatus for combinatorial synthesis

    Johnnie Engelhardt;David G. Gorenstein;Bruce A. Luxon

  • Structure of glucagon-like peptide (7-36) amide in a dodecylphosphocholine micelle as determined by 2D NMR

    Kevin Thornton;David G. Gorenstein

  • Nuclear magnetic resonance evidence for the pathways of pseudorotation in alkyloxyphosphoranes

    David Gorenstein;F. H. Westheimer

Frequent Co-Authors

Alan D.T. Barrett
Alan D.T. Barrett The University of Texas Medical Branch at Galveston
Mauro Ferrari
Mauro Ferrari Houston Methodist
Kazunari Taira
Kazunari Taira University of Tokyo
David W.C. Beasley
David W.C. Beasley The University of Texas Medical Branch at Galveston
Dinesh O. Shah
Dinesh O. Shah University of Florida
Hallgeir Rui
Hallgeir Rui Medical College of Wisconsin
Robert E. Shope
Robert E. Shope The University of Texas Medical Branch at Galveston
Xuewu Liu
Xuewu Liu Houston Methodist
Donald M. Jerina
Donald M. Jerina National Institutes of Health
Jane M. Sayer
Jane M. Sayer National Institutes of Health

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