Thomas L. James

Overview

Best Publications

• Structure and mechanism

  Norman J. Oppenheimer;Thomas L. James

  1298
  Citations

• Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible.

  Donne Dg;Viles Jh;Groth D;Mehlhorn I

  878
  Citations

• DOCK 6: Combining techniques to model RNA–small molecule complexes

  P. Therese Lang;Scott R. Brozell;Sudipto Mukherjee;Eric F. Pettersen

  877
  Citations

• A theoretical study of distance determinations from NMR. Two-dimensional nuclear overhauser effect spectra

  Joe W Keepers;Thomas L James

  673
  Citations

• CHAPTER 2 – PRINCIPLES OF NUCLEAR MAGNETIC RESONANCE

  Thomas L. James

  617
  Citations

• Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform.

  Thomas L. James;He Liu;Nikolai B. Ulyanov;Shauna Farr-Jones

  609
  Citations

• Nuclear Magnetic Resonance in Biochemistry

  Thomas L. James

  490
  Citations

• Perspectives on NMR in drug discovery: a technique comes of age

  Maurizio Pellecchia;Ivano Bertini;David Cowburn;Claudio Dalvit

  481
  Citations

• A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform.

  D Peretz;R A Williamson;Y Matsunaga;H Serban

  439
  Citations

• MARDIGRAS : a procedure for matrix analysis of relaxation for discerning geometry of an aqueous structure

  Brandan A Borgias;Thomas L James

  388
  Citations

• Solution structure of Syrian hamster prion protein rPrP(90-231).

  He Liu;Shauna Farr-Jones;Nikolai B. Ulyanov;Manuel Llinas

  271
  Citations

• COMATOSE, a method for constrained refinement of macromolecular structure based on two-dimensional nuclear overhauser effect spectra

  Brandan A Borgias;Thomas L James

  270
  Citations

• Conformational transitions in peptides containing two putative alpha-helices of the prion protein.

  Hong Zhang;Kiyotoshi Kaneko;Jack T. Nguyen;Tatiana L. Livshits

  264
  Citations

• Magnetic resonance imaging and spectroscopy of hepatic iron overload.

  D D Stark;M E Moseley;B R Bacon;A A Moss

  262
  Citations

• NMR-Based Characterization of Phenothiazines as a RNA Binding Scaffold†

  Moriz Mayer;Thomas L James

  245
  Citations

• Relaxation matrix analysis of 2D NMR data

  Brandan A. Borgias;Miriam Gochin;Deborah J. Kerwood;Thomas L. James

  235
  Citations

• Structure of the dimer initiation complex of HIV-1 genomic RNA.

  Anwer Mujeeb;Jared L. Clever;Todd M. Billeci;Thomas L. James

  226
  Citations

• Protein solution structure determination using distances from two-dimensional nuclear Overhauser effect experiments: effect of approximations on the accuracy of derived structures.

  Paul D. Thomas;Vladimir J. Basus;Thomas L. James

  216
  Citations

• Phosphorothioate-modified oligodeoxyribonucleotides. III. NMR and UV spectroscopic studies of the Rp-Rp, Sp-Sp, and Rp-Sp duplexes, [d(GGSAATTCC)]2, derived from diastereomeric O-ethyl phosphorothioates.

  L A LaPlanche;T L James;C Powell;W D Wilson

  205
  Citations

• Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA.

  Kenneth E Lind;Zhihua Du;Koh Fujinaga;B.Matija Peterlin

  199
  Citations

• PHYSICOCHEMICAL CHARACTERIZATION OF LARGE UNILAMELLAR PHOSPHOLIPID-VESICLES PREPARED BY REVERSE-PHASE EVAPORATION

  Nejat Düzgüneş;Nejat Düzgüneş;Jan Wilschut;Keelung Hong;Robert Fraley

  199
  Citations