Pak H. Chan mostly deals with Ischemia, Superoxide dismutase, Oxidative stress, Pathology and Biochemistry. His study in Ischemia is interdisciplinary in nature, drawing from both Apoptosis, Endocrinology and Pharmacology. His research in Apoptosis focuses on subjects like Molecular biology, which are connected to Cytochrome c.
Pak H. Chan has included themes like Brain ischemia, Superoxide and Anatomy in his Endocrinology study. His biological study spans a wide range of topics, including Lipid peroxidation and Reactive oxygen species. His research investigates the connection with Oxidative stress and areas like Mitochondrion which intersect with concerns in Oxidative phosphorylation and SOD2.
His main research concerns Ischemia, Superoxide dismutase, Internal medicine, Endocrinology and Pathology. His research integrates issues of Anesthesia and Pharmacology, Neuroprotection in his study of Ischemia. His Superoxide dismutase research incorporates elements of Molecular biology, Reactive oxygen species and Superoxide.
His study focuses on the intersection of Endocrinology and fields such as Biochemistry with connections in the field of Astrocyte. In his study, Extravasation is inextricably linked to Evans Blue, which falls within the broad field of Pathology. His work carried out in the field of Apoptosis brings together such families of science as Mitochondrion and Cell biology.
His primary areas of study are Ischemia, Oxidative stress, Internal medicine, Endocrinology and Superoxide dismutase. His work deals with themes such as Anesthesia and Neuroscience, Neuroprotection, which intersect with Ischemia. His Oxidative stress study combines topics from a wide range of disciplines, such as Pathology, Programmed cell death and Cell biology.
His work investigates the relationship between Internal medicine and topics such as Cardiology that intersect with problems in Heart transplantation and Metformin. His Endocrinology study incorporates themes from Glyceraldehyde 3-phosphate dehydrogenase and Phosphorylation. His Superoxide dismutase study is concerned with the larger field of Biochemistry.
His primary scientific interests are in Oxidative stress, Superoxide dismutase, Ischemia, Endocrinology and Internal medicine. The study incorporates disciplines such as Reactive oxygen species, Programmed cell death and Mitochondrion in addition to Superoxide dismutase. His research in Ischemia intersects with topics in Brain damage and Neuroprotection.
His Neuroprotection research incorporates themes from STAT3, Brain ischemia, SOD2 and Pathology. His SOD1 research is multidisciplinary, relying on both Apoptosis and Immunology. Pak H. Chan has researched NADPH oxidase in several fields, including Superoxide and Pentose phosphate pathway.
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Reactive oxygen radicals in signaling and damage in the ischemic brain.
Pak H. Chan.
Journal of Cerebral Blood Flow and Metabolism (2001)
Dilated Cardiomyopathy and Neonatal Lethality in Mutant Mice Lacking Manganese Superoxide Dismutase
Yibing Li;Ting-Ting Huang;Elaine J. Carlson;Simon Melov.
Nature Genetics (1995)
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke.
Geoffrey T. Manley;Miki Fujimura;Tonghui Ma;Nobuo Noshita.
Nature Medicine (2000)
Role of Oxidants in Ischemic Brain Damage
Pak H. Chan.
A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window.
Juha Yrjänheikki;Tiina Tikka;Riitta Keinänen;Gundars Goldsteins.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Free Radical Pathways in CNS Injury
Anders Lewén;Paul Matz;Pak H. Chan.
Journal of Neurotrauma (2000)
Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase.
Hiroyuki Kinouchi;Charles J. Epstein;Takuji Mizui;Elaine Carlson.
Proceedings of the National Academy of Sciences of the United States of America (1991)
Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection
Hai Chen;Hideyuki Yoshioka;Gab Seok Kim;Joo Eun Jung.
Antioxidants & Redox Signaling (2011)
Mitochondrial Susceptibility to Oxidative Stress Exacerbates Cerebral Infarction That Follows Permanent Focal Cerebral Ischemia in Mutant Mice with Manganese Superoxide Dismutase Deficiency
Kensuke Murakami;Takeo Kondo;Makoto Kawase;Makoto Kawase;Yibing Li.
The Journal of Neuroscience (1998)
Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia.
G Yang;P H Chan;J Chen;E Carlson.
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