World's Best Scientists 2026 revealed!

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Medicine

D-Index
123
Citations
52308
World Ranking
3370
National Ranking
1852

Overview

Pak H. Chan is affiliated with Stanford University in the United States and conducts research primarily in the field of Medicine. Their work spans several subfields, including Rheumatology, Neurology, and Surgery.

The scientist's recent publications focus on topics related to oropharyngeal anatomy, facial nerve pathology, and anomalies affecting the head and neck region. Main topics of their research include:

  • Oropharyngeal Anatomy and Pathologies
  • Facial Nerve Paralysis Treatment and Research
  • Head and Neck Anomalies

Pak H. Chan frequently publishes in the Journal of Craniofacial Surgery. Their latest paper, titled Variation and Arrangement of the Digastric Muscle in a Chinese Population, was published in 2024 in this journal.

Collaboration is a notable aspect of their research practice. Pak H. Chan has coauthored work with several researchers, including:

  • Bo Shen
  • Ming Tang
  • Xuliang Zhuang
  • Yongjie Zhang

Their research contributions involve detailed investigations in anatomy and pathology related to the oropharyngeal region, as well as clinical research on facial nerve paralysis and various structural anomalies in the head and neck. These topics are addressed through a combination of clinical observation and anatomical study, contributing to a multidisciplinary understanding in medicine.

Best Publications

  • Reactive oxygen radicals in signaling and damage in the ischemic brain.

    Pak H. Chan

  • Dilated Cardiomyopathy and Neonatal Lethality in Mutant Mice Lacking Manganese Superoxide Dismutase

    Yibing Li;Ting-Ting Huang;Elaine J. Carlson;Simon Melov

  • Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke.

    Geoffrey T. Manley;Miki Fujimura;Tonghui Ma;Nobuo Noshita

  • Role of Oxidants in Ischemic Brain Damage

    Pak H. Chan

  • A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window.

    Juha Yrjänheikki;Tiina Tikka;Riitta Keinänen;Gundars Goldsteins

  • Free Radical Pathways in CNS Injury

    Anders Lewén;Paul Matz;Pak H. Chan

  • Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

    Hai Chen;Hideyuki Yoshioka;Gab Seok Kim;Joo Eun Jung

  • Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase.

    Hiroyuki Kinouchi;Charles J. Epstein;Takuji Mizui;Elaine Carlson

  • Mitochondrial Susceptibility to Oxidative Stress Exacerbates Cerebral Infarction That Follows Permanent Focal Cerebral Ischemia in Mutant Mice with Manganese Superoxide Dismutase Deficiency

    Kensuke Murakami;Takeo Kondo;Makoto Kawase;Makoto Kawase;Yibing Li

  • Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia.

    G Yang;P H Chan;J Chen;E Carlson

  • Reduction of CuZn-Superoxide Dismutase Activity Exacerbates Neuronal Cell Injury and Edema Formation after Transient Focal Cerebral Ischemia

    Takeo Kondo;Andrew G. Reaume;Ting Ting Huang;Elaine Carlson

  • NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

    Angela M Brennan;Sang Won Suh;Seok Joon Won;Purnima Narasimhan

  • Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia.

    Jeffrey M. Gidday;Yvan G. Gasche;Yvan G. Gasche;Jean C. Copin;Jean C. Copin;Aarti R. Shah

  • Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood-brain barrier dysfunction.

    Yvan Gasche;Miki Fujimura;Yuiko Morita-Fujimura;Jean Christophe Copin

  • Brain injury, edema, and vascular permeability changes induced by oxygen‐derived free radicals

    Pak Hoo Chan;James W. Schmidley;Robert A. Fishman;Susan M. Longar

  • Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival

    Kuniyasu Niizuma;Hidenori Endo;Pak H. Chan

  • Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia.

    Yvan Gasche;Jean Christophe Copin;Jean Christophe Copin;Taku Sugawara;Miki Fujimura

  • Overexpression of SOD1 in Transgenic Rats Protects Vulnerable Neurons Against Ischemic Damage After Global Cerebral Ischemia and Reperfusion

    Pak H. Chan;Makoto Kawase;Kensuke Murakami;Sylvia F. Chen

  • Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase

    Sang Won Suh;Elizabeth T. Gum;Aaron M. Hamby;Pak H. Chan

  • Temporal profile of angiogenesis and expression of related genes in the brain after ischemia

    Takeshi Hayashi;Nobuo Noshita;Taku Sugawara;Pak H Chan

Frequent Co-Authors

Charles J. Epstein
Charles J. Epstein University of California, San Francisco
Jari Koistinaho
Jari Koistinaho University of Helsinki
Frank R. Sharp
Frank R. Sharp University of California, Davis
Guo-Yuan Yang
Guo-Yuan Yang Shanghai Jiao Tong University
Philip Weinstein
Philip Weinstein University of Adelaide
Thomas L. James
Thomas L. James University of California, San Francisco
Raymond A. Swanson
Raymond A. Swanson University of California, San Francisco
Stephen M. Sagar
Stephen M. Sagar University of California, San Francisco
Ting-Ting Huang
Ting-Ting Huang Stanford University
Koji Abe
Koji Abe Okayama University

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