D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 121 Citations 49,026 342 World Ranking 2042 National Ranking 1186

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Pak H. Chan mostly deals with Ischemia, Superoxide dismutase, Oxidative stress, Pathology and Biochemistry. His study in Ischemia is interdisciplinary in nature, drawing from both Apoptosis, Endocrinology and Pharmacology. His research in Apoptosis focuses on subjects like Molecular biology, which are connected to Cytochrome c.

Pak H. Chan has included themes like Brain ischemia, Superoxide and Anatomy in his Endocrinology study. His biological study spans a wide range of topics, including Lipid peroxidation and Reactive oxygen species. His research investigates the connection with Oxidative stress and areas like Mitochondrion which intersect with concerns in Oxidative phosphorylation and SOD2.

His most cited work include:

  • Dilated Cardiomyopathy and Neonatal Lethality in Mutant Mice Lacking Manganese Superoxide Dismutase (1557 citations)
  • Reactive oxygen radicals in signaling and damage in the ischemic brain. (1337 citations)
  • Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. (1191 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Ischemia, Superoxide dismutase, Internal medicine, Endocrinology and Pathology. His research integrates issues of Anesthesia and Pharmacology, Neuroprotection in his study of Ischemia. His Superoxide dismutase research incorporates elements of Molecular biology, Reactive oxygen species and Superoxide.

His study focuses on the intersection of Endocrinology and fields such as Biochemistry with connections in the field of Astrocyte. In his study, Extravasation is inextricably linked to Evans Blue, which falls within the broad field of Pathology. His work carried out in the field of Apoptosis brings together such families of science as Mitochondrion and Cell biology.

He most often published in these fields:

  • Ischemia (40.06%)
  • Superoxide dismutase (32.28%)
  • Internal medicine (31.70%)

What were the highlights of his more recent work (between 2006-2019)?

  • Ischemia (40.06%)
  • Oxidative stress (24.50%)
  • Internal medicine (31.70%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Ischemia, Oxidative stress, Internal medicine, Endocrinology and Superoxide dismutase. His work deals with themes such as Anesthesia and Neuroscience, Neuroprotection, which intersect with Ischemia. His Oxidative stress study combines topics from a wide range of disciplines, such as Pathology, Programmed cell death and Cell biology.

His work investigates the relationship between Internal medicine and topics such as Cardiology that intersect with problems in Heart transplantation and Metformin. His Endocrinology study incorporates themes from Glyceraldehyde 3-phosphate dehydrogenase and Phosphorylation. His Superoxide dismutase study is concerned with the larger field of Biochemistry.

Between 2006 and 2019, his most popular works were:

  • Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection (488 citations)
  • NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation (402 citations)
  • Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase (329 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His primary scientific interests are in Oxidative stress, Superoxide dismutase, Ischemia, Endocrinology and Internal medicine. The study incorporates disciplines such as Reactive oxygen species, Programmed cell death and Mitochondrion in addition to Superoxide dismutase. His research in Ischemia intersects with topics in Brain damage and Neuroprotection.

His Neuroprotection research incorporates themes from STAT3, Brain ischemia, SOD2 and Pathology. His SOD1 research is multidisciplinary, relying on both Apoptosis and Immunology. Pak H. Chan has researched NADPH oxidase in several fields, including Superoxide and Pentose phosphate pathway.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Reactive oxygen radicals in signaling and damage in the ischemic brain.

Pak H. Chan.
Journal of Cerebral Blood Flow and Metabolism (2001)

2234 Citations

Dilated Cardiomyopathy and Neonatal Lethality in Mutant Mice Lacking Manganese Superoxide Dismutase

Yibing Li;Ting-Ting Huang;Elaine J. Carlson;Simon Melov.
Nature Genetics (1995)

2109 Citations

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke.

Geoffrey T. Manley;Miki Fujimura;Tonghui Ma;Nobuo Noshita.
Nature Medicine (2000)

1905 Citations

Role of Oxidants in Ischemic Brain Damage

Pak H. Chan.
Stroke (1996)

1510 Citations

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window.

Juha Yrjänheikki;Tiina Tikka;Riitta Keinänen;Gundars Goldsteins.
Proceedings of the National Academy of Sciences of the United States of America (1999)

1233 Citations

Free Radical Pathways in CNS Injury

Anders Lewén;Paul Matz;Pak H. Chan.
Journal of Neurotrauma (2000)

1097 Citations

Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase.

Hiroyuki Kinouchi;Charles J. Epstein;Takuji Mizui;Elaine Carlson.
Proceedings of the National Academy of Sciences of the United States of America (1991)

861 Citations

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

Hai Chen;Hideyuki Yoshioka;Gab Seok Kim;Joo Eun Jung.
Antioxidants & Redox Signaling (2011)

851 Citations

Mitochondrial Susceptibility to Oxidative Stress Exacerbates Cerebral Infarction That Follows Permanent Focal Cerebral Ischemia in Mutant Mice with Manganese Superoxide Dismutase Deficiency

Kensuke Murakami;Takeo Kondo;Makoto Kawase;Makoto Kawase;Yibing Li.
The Journal of Neuroscience (1998)

694 Citations

Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia.

G Yang;P H Chan;J Chen;E Carlson.
Stroke (1994)

664 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Pak H. Chan

Mark P. Mattson

Mark P. Mattson

Johns Hopkins University School of Medicine

Publications: 120

Alan S. Verkman

Alan S. Verkman

University of California, San Francisco

Publications: 120

Eng H. Lo

Eng H. Lo

Harvard University

Publications: 114

John H. Zhang

John H. Zhang

Loma Linda University

Publications: 106

Raymond A. Swanson

Raymond A. Swanson

University of California, San Francisco

Publications: 78

Guo-Yuan Yang

Guo-Yuan Yang

Shanghai Jiao Tong University

Publications: 75

Moo-Ho Won

Moo-Ho Won

Kangwon National University

Publications: 74

Midori A. Yenari

Midori A. Yenari

University of California, San Francisco

Publications: 74

Susan C. Fagan

Susan C. Fagan

University of Georgia

Publications: 73

Koji Abe

Koji Abe

Okayama University

Publications: 73

Charles J. Epstein

Charles J. Epstein

University of California, San Francisco

Publications: 68

Patrick M. Kochanek

Patrick M. Kochanek

University of Pittsburgh

Publications: 65

Frank R. Sharp

Frank R. Sharp

University of California, Davis

Publications: 60

Arlan Richardson

Arlan Richardson

University of Oklahoma Health Sciences Center

Publications: 59

Steven H. Graham

Steven H. Graham

University of Pittsburgh

Publications: 56

Michael Chopp

Michael Chopp

Oakland University

Publications: 56

Trending Scientists

Ramón Quintanilla

Ramón Quintanilla

Universitat Politècnica de Catalunya

Robert M. Corless

Robert M. Corless

University of Western Ontario

Jianfeng Ma

Jianfeng Ma

Xidian University

Hyun-Joong Chung

Hyun-Joong Chung

University of Alberta

Gary L. Glish

Gary L. Glish

University of North Carolina at Chapel Hill

Dennis G. Hall

Dennis G. Hall

University of Alberta

Noel W. Cant

Noel W. Cant

Macquarie University

Paul C. J. Kamer

Paul C. J. Kamer

University of Amsterdam

Neeraj Kumar

Neeraj Kumar

Council for Scientific and Industrial Research

Matjaz Valant

Matjaz Valant

University of Nova Gorica

Nico P. Dantuma

Nico P. Dantuma

Karolinska Institute

Colin Campbell

Colin Campbell

University of York

Rob L. Evans

Rob L. Evans

Woods Hole Oceanographic Institution

Suzanne L. Baldwin

Suzanne L. Baldwin

Syracuse University

Susan M. Landau

Susan M. Landau

University of California, Berkeley

Zhi-Yong Yang

Zhi-Yong Yang

Sanofi (United States)

Something went wrong. Please try again later.