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Medicine

D-Index
77
Citations
22319
World Ranking
18409
National Ranking
9183

Research.com Recognitions

  • 2019 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Steven H. Graham is affiliated with the University of Pittsburgh in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a total of 11 publications contributing to these areas.

The subfields of study within their work include Molecular Biology, Epidemiology, Cellular and Molecular Neuroscience, Physiology, and Cell Biology. This range reflects a focus on molecular mechanisms relevant to health and disease.

The main research topics covered include:

  • Mitochondrial Function and Pathology
  • Ubiquitin and proteasome pathways
  • Metabolomics and Mass Spectrometry Studies
  • Genetic Neurodegenerative Diseases
  • Biochemical effects in animals
  • Muscle metabolism and nutrition
  • Cancer, Hypoxia, and Metabolism

The scientist has frequently published in several journals, among them:

  • Experimental Neurology
  • Ageing Research Reviews
  • Journal of Cerebral Blood Flow & Metabolism
  • Neuroscience
  • Community Literacy Journal

Steven H. Graham has authored multiple research papers, with recent notable publications including:

  • "Role of UCHL1 in the pathogenesis of neurodegenerative diseases and brain injury" (2023) in Ageing Research Reviews
  • "Abolishing UCHL1's hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice" (2020) in Experimental Neurology
  • "Mutation of a Ubiquitin Carboxy Terminal Hydrolase L1 Lipid Binding Site Alleviates Cell Death, Axonal Injury, and Behavioral Deficits After Traumatic Brain Injury in Mice" (2021) in Neuroscience
  • "Abolishing UCHL1's hydrolase activity exacerbates ischemia-induced axonal injury and functional deficits in mice" (2024) in Journal of Cerebral Blood Flow & Metabolism
  • "Systemic treatment with ubiquitin carboxy terminal hydrolase L1 TAT protein ameliorates axonal injury and reduces functional deficits after traumatic brain injury in mice" (2023) in Experimental Neurology

Frequent co-authors collaborating with Steven H. Graham include:

  • Zhiping Mi
  • Marie E. Rose
  • Jie Ma
  • Hao Liu
  • Xiecheng Ma

A notable award in Steven H. Graham's career is the Fellow of the American Association for the Advancement of Science (AAAS), awarded in 2019.

Best Publications

  • Adverse Cerebral Outcomes after Coronary Bypass Surgery

    G W Roach;M Kanchuger;C M Mangano;M Newman

  • Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia.

    Jun Chen;Tetsuya Nagayama;Kunlin Jin;R. Anne Stetler;R. Anne Stetler

  • Programmed Cell Death in Cerebral Ischemia

    Steven H. Graham;Jun Chen

  • Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures

    Tetsuya Nagayama;Amy D. Sinor;Roger P. Simon;Jun Chen

  • In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis

    Guodong Cao;Wei Pei;Hailiang Ge;Qinhua Liang

  • Caspase-3 mediated neuronal death after traumatic brain injury in rats.

    R. S. B. Clark;P. M. Kochanek;S. C. Watkins;Minzhi Chen

  • Stress proteins and tolerance to focal cerebral ischemia

    Jun Chen;Steven H. Graham;Raymond L. Zhu;Roger P. Simon

  • Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia.

    Masaki Nakayama;Koichi Uchimura;Raymond Li Zhu;Tetsuya Nagayama

  • Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway.

    Lina Du;Hülya Bayir;Yichen Lai;Xiaopeng Zhang

  • Cerebral Injury After Cardiac Surgery: Identification of a Group at Extraordinary Risk

    Richard L. Wolman;Nancy A. Nussmeier;Anil Aggarwal;Marc S. Kanchuger

  • Intra-mitochondrial Poly(ADP-ribosylation) Contributes to NAD+ Depletion and Cell Death Induced by Oxidative Stress *

    Lina Du;Xiaopeng Zhang;Yong Y. Han;Nancy A. Burke

  • Critical Role of Calpain I in Mitochondrial Release of Apoptosis-Inducing Factor in Ischemic Neuronal Injury

    Guodong Cao;Juan Xing;Xiao Xiao;Anthony K.F. Liou

  • Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury

    R. S. B. Clark;P. M. Kochanek;Minzhi Chen;S. C. Watkins

  • Apoptosis-Suppressor Gene bcl-2 Expression after Traumatic Brain Injury in Rats

    Robert S. B. Clark;Jun Chen;Simon C. Watkins;Patrick M. Kochanek

  • Apoptosis Repressor Genes Bcl-2 and Bcl-x-long are Expressed in the Rat Brain Following Global Ischemia

    Jun Chen;Steven H. Graham;Masaki Nakayama;Raymond L. Zhu

  • Expression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia.

    Chen J;Zhu Rl;Nakayama M;Kawaguchi K

  • Oxidative stress following traumatic brain injury in rats: quantitation of biomarkers and detection of free radical intermediates.

    Vladimir A. Tyurin;Yulia Y. Tyurina;Grigory G. Borisenko;Tatiana V. Sokolova

  • Intracellular Bax translocation after transient cerebral ischemia: implications for a role of the mitochondrial apoptotic signaling pathway in ischemic neuronal death.

    Guodong Cao;Manabu Minami;Wei Pei;Chaohua Yan

  • Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury.

    Marie E Rose;Michele B Huerbin;John Melick;Donald W Marion

  • Neuroprotection against Focal Ischemic Brain Injury by Inhibition of c-Jun N-Terminal Kinase and Attenuation of the Mitochondrial Apoptosis-Signaling Pathway

    Yanqin Gao;Armando P. Signore;Wei Yin;Guodong Cao

Frequent Co-Authors

Patrick M. Kochanek
Patrick M. Kochanek University of Pittsburgh
Robert S. B. Clark
Robert S. B. Clark University of Pittsburgh
Kunlin Jin
Kunlin Jin University of North Texas Health Science Center
Donald W. Marion
Donald W. Marion United States Army Research Laboratory
C. Edward Dixon
C. Edward Dixon University of Pittsburgh
Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Philip Weinstein
Philip Weinstein University of Adelaide
David A. Greenberg
David A. Greenberg Buck Institute for Research on Aging
R. Anne Stetler
R. Anne Stetler University of Pittsburgh
Roger P. Simon
Roger P. Simon Morehouse School of Medicine

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