What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Enzyme
The scientist’s investigation covers issues in Virology, Immunology, Molecular biology, Scrapie and Cell biology.
His research integrates issues of Bovine spongiform encephalopathy, PrPSc Proteins, Pathogenesis and PRNP in his study of Virology.
His Immunology study combines topics from a wide range of disciplines, such as Cancer research and Central nervous system.
The study incorporates disciplines such as Recombinant DNA, Transcription factor, Mutant, Knockout mouse and Gene in addition to Molecular biology.
His research on Scrapie also deals with topics like
- Transgene together with Ataxia and Amyloid,
- Astrocyte most often made with reference to Genetically modified mouse.
The Cell biology study combines topics in areas such as Glutamate receptor, Receptor, Genetics and Downregulation and upregulation.
His most cited work include:
- Mice devoid of PrP are resistant to scrapie (1803 citations)
- Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud. (1147 citations)
- Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation (821 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Virology, Immunology, Cell biology, Pathology and Scrapie.
His Virology research is multidisciplinary, relying on both Pathogenesis, Bovine spongiform encephalopathy, PRNP, Disease and Genetically modified mouse.
In Genetically modified mouse, Adriano Aguzzi works on issues like Molecular biology, which are connected to Mutant.
Much of his study explores Immunology relationship to Central nervous system.
His Cell biology study which covers Neurodegeneration that intersects with Microglia and Neuroscience.
His work on PrPSc Proteins as part of general Scrapie study is frequently connected to Follicular dendritic cells, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
He most often published in these fields:
- Virology (29.90%)
- Immunology (18.85%)
- Cell biology (17.67%)
What were the highlights of his more recent work (between 2014-2021)?
- Cell biology (17.67%)
- Antibody (7.66%)
- Immunology (18.85%)
In recent papers he was focusing on the following fields of study:
Adriano Aguzzi mainly focuses on Cell biology, Antibody, Immunology, Pathogenesis and Neurodegeneration.
His Cell biology study integrates concerns from other disciplines, such as Scrapie, Neurotoxicity, Neuroprotection, Myelin and Receptor.
His Antibody study also includes
- Prion protein together with Toxicity,
- Immune system together with Knockout mouse.
The concepts of his Immunology study are interwoven with issues in Disease and PRNP.
His studies deal with areas such as Astrogliosis and Microglia as well as Pathogenesis.
His Neurodegeneration research includes elements of Biochemistry and Neuroscience, Central nervous system.
Between 2014 and 2021, his most popular works were:
- Phase Separation: Linking Cellular Compartmentalization to Disease (171 citations)
- The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6 (112 citations)
- The biological function of the cellular prion protein: an update (108 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Enzyme
Immunology, Virology, Neurodegeneration, Cell biology and Pathogenesis are his primary areas of study.
The Immunology study which covers Oxidative stress that intersects with Amyotrophic lateral sclerosis.
His Virology research includes themes of Genetics, Antibody, Pharmacological interventions, Disease course and Toxicity.
His work deals with themes such as Axoplasmic transport, Neurotoxicity and Biochemistry, which intersect with Neurodegeneration.
His biological study spans a wide range of topics, including Myelin and Programmed cell death.
His study in Pathogenesis is interdisciplinary in nature, drawing from both Scrapie, Calreticulin, Microglia and Neuroscience, Neuroprotection.
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