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Molecular Biology

D-Index
107
Citations
46026
World Ranking
411
National Ranking
237

Research.com Recognitions

  • 2003 - Warren Alpert Foundation Prize For their pioneering work on the purification, characterization, and cloning of human interferon-alpha.
  • 1996 - GlaxoSmithKline Prize, Royal Society of London in recognition of his work on prion diseases which lead to the remarkable advances in understanding the molecular biology of spongiform encephalopathies
  • 1995 - Robert Koch Gold Medal
  • 1989 - Member of Academia Europaea
  • 1989 - Member of the National Academy of Sciences
  • 1985 - Fellow of the American Academy of Arts and Sciences
  • 1983 - Fellow of the Royal Society, United Kingdom
  • 1980 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Human Genetics and Molecular Medicine
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Charles Weissmann is affiliated with the University of Florida in the United States. Their work spans several decades and has been recognized by numerous awards reflecting contributions to molecular biology, genetics, and related biomedical sciences.

They have been honored with prestigious awards including the Warren Alpert Foundation Prize in 2003 for pioneering work on the purification, characterization, and cloning of human interferon-alpha. Earlier, in 1996, Charles Weissmann received the GlaxoSmithKline Prize from the Royal Society of London, acknowledging their contributions to prion diseases and significant advances in understanding the molecular biology of spongiform encephalopathies.

Additional distinctions include the Robert Koch Gold Medal awarded in 1995 and membership in various academies and organizations. These include election to the National Academy of Sciences and Academia Europaea in 1989, fellowship of the American Academy of Arts and Sciences in 1985, and fellowship of the Royal Society of the United Kingdom in 1983. Charles Weissmann is also recognized by the German National Academy of Sciences Leopoldina for human genetics and molecular medicine since 1980. Fellowships in The Academy of Medical Sciences, United Kingdom, and membership in the European Molecular Biology Organization are also noted.

The scientist's expertise covers main fields and subfields broadly related to genetics, molecular biology, and medicine, particularly focusing on infectious diseases and protein characterization at the molecular level. Their research interests intersect areas such as human interferon-alpha and prion biology, contributing to the molecular understanding of neurodegenerative diseases caused by spongiform encephalopathies.

While recent papers, frequent co-authors, publication venues, book publications, and detailed topics of work are not specified, the awards and affiliations hint at a strong focus on molecular medicine and genetics, underpinned by experimental and theoretical approaches to biomolecular phenomena. This profile aligns with a career dedicated to advancing biomedical science through molecular and genetic research applied to human disease mechanisms.

Best Publications

  • A rapid, sensitive, and specific method for the determination of protein in dilute solution

    W. Schaffner;C. Weissmann

  • Mice devoid of PrP are resistant to scrapie

    H. Büeler;A. Aguzzi;A. Sailer;R.-A. Greiner

  • Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

    Hansruedi Büeler;Marek Fischer;Yolande Lang;Yolande Lang;Horst Bluethmann;Horst Bluethmann

  • A cellular gene encodes scrapie PrP 27-30 protein

    Bruno Oesch;Bruno Oesch;David Westaway;Monika Wälchli;Monika Wälchli;Michael P. McKinley

  • Mapping of RNA by a modification of the Berk-Sharp procedure: the 5' termini of 15 S beta-globin mRNA precursor and mature 10 s beta-globin mRNA have identical map coordinates.

    Robert F. Weaver;Charles Weissmann

  • Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene

    K. Basler;B. Oesch;M. Scott;D. Westaway

  • Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.

    M B Fischer;T Rülicke;A Raeber;A Sailer

  • Normal host prion protein necessary for scrapie-induced neurotoxicity

    Sebastian Brandner;Stefan Isenmann;Alex Raeber;Marek Fischer

  • Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase.

    Yi-Li Yang;L. F. L. Reis;J. Pavlovic;A. Aguzzi

  • Nucleotide sequence heterogeneity of an RNA phage population

    Esteban Domingo;Donna Sabo;Tadatsugu Taniguchi;Charles Weissmann

  • Mx protein: Constitutive expression in 3T3 cells transformed with cloned Mx cDNA confers selective resistance to influenza virus

    P. Staeheli;O. Haller;W. Boll;J. Lindenmann

  • Synthesis in E. coli of a polypeptide with human leukocyte interferon activity

    Shigekazu Nagata;Hideharu Taira;Alan Hall;Lorraine Johnsrud

  • Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.

    Doron Shmerling;Ivan Hegyi;Marek Fischer;Thomas Blättler

  • Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

    Peter Dierks;Albert van Ooyen;Mark D. Cochran;Carl Dobkin

  • Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

    Masato Enari;Eckhard Flechsig;Charles Weissmann

  • The structure of one of the eight or more distinct chromosomal genes for human interferon- α

    Shigekazu Nagata;Ned Mantei;Charles Weissmann

  • Darwinian evolution of prions in cell culture.

    Jiali Li;Shawn Browning;Sukhvir P. Mahal;Anja M. Oelschlegel

  • A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

    Sandy D. Der;Yi Li Yang;Charles Weissmann;Bryan R.G. Williams

  • The state of the prion.

    Charles Weissmann

  • The interferon genes.

    Charles Weissmann;Hans Weber

Frequent Co-Authors

Adriano Aguzzi
Adriano Aguzzi University of Zurich
Marek Fischer
Marek Fischer University of Zurich
Sebastian Brandner
Sebastian Brandner University College London
Michel Aguet
Michel Aguet École Polytechnique Fédérale de Lausanne
Rolf M. Zinkernagel
Rolf M. Zinkernagel University of Zurich
Martin A. Billeter
Martin A. Billeter University of Zurich
Shigekazu Nagata
Shigekazu Nagata Osaka University
Thomas Rülicke
Thomas Rülicke University of Veterinary Medicine Vienna
Tadatsugu Taniguchi
Tadatsugu Taniguchi University of Tokyo
Richard A. Flavell
Richard A. Flavell Yale University

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