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Biology and Biochemistry

D-Index
75
Citations
19899
World Ranking
5321
National Ranking
150

Overview

Sylvain Lehmann is affiliated with the University of Montpellier in France and has contributed extensively to research in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans several subfields, including Molecular Biology, Physiology, Neurology, Psychiatry and Mental Health, and Hematology.

Lehmann's work focuses primarily on topics related to neurodegenerative and neurological disorders. Major areas of study include Alzheimer's disease research and treatments, dementia and cognitive impairment research, amyotrophic lateral sclerosis research, S100 proteins and annexins, Parkinson's disease mechanisms and treatments, acute myeloid leukemia research, and multiple sclerosis research studies.

Significant recent publications by Lehmann include:

  • A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease, 2020, Nature Medicine
  • Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study, 2020, The Lancet
  • Neurofilaments as biomarkers in neurological disorders - towards clinical application, 2024, Nature Reviews Neurology
  • Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer's disease and PET amyloid-positive patient identification, 2020, Alzheimer s Research & Therapy
  • Serum GFAP in multiple sclerosis: correlation with disease type and MRI markers of disease severity, 2020, Scientific Reports

Lehmann has collaborated frequently with several researchers, including Christophe Hirtz, Constance Delaby, Audrey Gabelle, Jérôme Vialaret, and Susanna Schraen-Maschke.

The scientist's publications appear regularly in specific venues such as:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer s Research & Therapy
  • Scientific Reports
  • Revue Neurologique

Best Publications

  • Signal transduction through prion protein.

    Sophie Mouillet-Richard;Myriam Ermonval;C Chebassier;J L Laplanche

  • SULFATED GLYCANS STIMULATE ENDOCYTOSIS OF THE CELLULAR ISOFORM OF THE PRION PROTEIN, PRPC, IN CULTURED CELLS

    Show Ling Shyng;Sylvain Lehmann;Krista L. Moulder;David A. Harris

  • A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease.

    Nicolas R Barthélemy;Yan Li;Nelly Joseph-Mathurin;Brian A Gordon

  • Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state

    Laure Lapasset;Ollivier Milhavet;Alexandre Prieur;Emilie Besnard

  • Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer's Disease.

    Oskar Hansson;Sylvain Lehmann;Markus Otto;Henrik Zetterberg;Henrik Zetterberg

  • Cell specific differences between human adipose-derived and mesenchymal–stromal cells despite similar differentiation potentials

    Danièle Noël;David Caton;Stéphane Roche;Claire Bony;Claire Bony

  • Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study

    J. Kuhle;G. Disanto;R. Dobson;R. Adiutori

  • Screening of 145 anti-PrP monoclonal antibodies for their capacity to inhibit PrPSc replication in infected cells.

    Cécile Féraudet;Nathalie Morel;Stéphanie Simon;Hervé Volland

  • Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update

    Marta del Campo;Brit Mollenhauer;Antonio Bertolotto;Sebastiaan Engelborghs

  • Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study

    Juan Fortea;Eduard Vilaplana;Maria Carmona-Iragui;Bessy Benejam

  • Successful Transmission of Three Mouse-Adapted Scrapie Strains to Murine Neuroblastoma Cell Lines Overexpressing Wild-Type Mouse Prion Protein

    Noriyuki Nishida;David A. Harris;Didier Vilette;Hubert Laude

  • Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein

    D. Vilette;O. Andreoletti;F. Archer;M. F. Madelaine

  • Prion infection impairs the cellular response to oxidative stress

    Ollivier Milhavet;Hilary E. M. McMahon;Walid Rachidi;Noriyuki Nishida

  • Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival

    Suzhen Chen;Alain Mangé;Ling Dong;Sylvain Lehmann

  • Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper

    J. Bousquet;W. Fokkens;P. Burney;S. R. Durham

  • Expression of Prion Protein Increases Cellular Copper Binding and Antioxidant Enzyme Activities but Not Copper Delivery

    Walid Rachidi;Didier Vilette;Pascale Guiraud;Marie Arlotto

  • Oxidative stress and the prion protein in transmissible spongiform encephalopathies.

    Ollivier Milhavet;Sylvain Lehmann

  • Blockade of Glycosylation Promotes Acquistion of Scrapie-like Properties by the Prion Protein in Cultured Cells

    Sylvain Lehmann;David A. Harris

  • EVIDENCE FOR A SIX-TRANSMEMBRANE DOMAIN STRUCTURE OF PRESENILIN 1

    Sylvain Lehmann;Roberto Chiesa;David A. Harris

  • Cationic phosphorus-containing dendrimers reduce prion replication both in cell culture and in mice infected with scrapie.

    Jérôme Solassol;Carole Crozet;Véronique Perrier;Julien Leclaire

Frequent Co-Authors

Yves Dauvilliers
Yves Dauvilliers University of Montpellier
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg
David A. Harris
David A. Harris Boston University
Alberto Lleó
Alberto Lleó Hospital de la Santa Creu i Sant Pau
Jacques Grassi
Jacques Grassi French Alternative Energies and Atomic Energy Commission (CEA)
Florence Pasquier
Florence Pasquier University of Lille
Luc Buée
Luc Buée University of Lille
Kaj Blennow
Kaj Blennow University of Gothenburg

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