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Jacques Hugon

Jacques Hugon

D-Index & Metrics

Neuroscience

D-Index
66
Citations
13692
World Ranking
3039
National Ranking
107

Overview

Jacques Hugon is affiliated with Inserm in France and has contributed extensively to the fields of medicine and neuroscience. Their research primarily focuses on neurology, physiology, psychiatry and mental health, molecular biology, and critical care and intensive care medicine.

The main topics covered in their work include:

  • Alzheimer's disease research and treatments
  • Dementia and Cognitive Impairment Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Long-Term Effects of COVID-19
  • Tryptophan and brain disorders
  • Intensive Care Unit Cognitive Disorders
  • Mitochondrial Function and Pathology

Notable recent publications by Jacques Hugon include:

  • Long COVID: cognitive complaints (brain fog) and dysfunction of the cingulate cortex, 2021, Journal of Neurology
  • Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum, 2021, JAMA Neurology
  • Dissection of synaptic pathways through the CSF biomarkers for predicting Alzheimer disease, 2020, Neurology
  • STAT3 inhibition protects against neuroinflammation and BACE1 upregulation induced by systemic inflammation, 2020, Immunology Letters
  • Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study, 2020, PLoS Medicine

Jacques Hugon frequently publishes in the following venues:

  • Alzheimer's Research & Therapy
  • Alzheimer's & Dementia
  • Journal of Alzheimer's Disease
  • Revue Neurologique
  • Research Square

Frequent collaborators in their work include Claire Paquet, Julien Dumurgier, Emmanuel Cognat, François Mouton-Liger, and Claire Hourrègue, reflecting long-term partnerships progressing research in their fields of study.

Best Publications

  • Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin

    Peter S. Spencer;Peter B. Nunn;Jacques Hugon;Albert C. Ludolph

  • LATHYRISM: EVIDENCE FOR ROLE OF THE NEUROEXCITATORY AMINOACID BOAA

    Peter S. Spencer;Albert Ludolph;M. P. Dwivedi;Dwijendra N. Roy

  • Abnormal retinal thickness in patients with mild cognitive impairment and Alzheimer's disease

    Claire Paquet;Michèle Boissonnot;Florent Roger;Paul Dighiero

  • Phosphorylation of eukaryotic initiation factor-2α (eIF2α) is associated with neuronal degeneration in Alzheimer's disease

    Raymond C.C. Chang;Ada K.Y. Wong;Ho Keung Ng;Jacques Hugon

  • CNTF promotes survival of retinal ganglion cells after induction of ocular hypertension in rats: the possible involvement of STAT3 pathway.

    Jianzhong Ji;Wassim Elyaman;Henry K. Yip;Vincent W.H. Lee;Vincent W.H. Lee

  • Cell culture evidence for neuronal degeneration in amyotrophic lateral sclerosis being linked to glutamate AMPA/kainate receptors

    P. Couratier;P. Sindou;J. Hugon;J.-M. Vallat

  • mTOR/p70S6k signalling alteration by Aβ exposure as well as in APP‐PS1 transgenic models and in patients with Alzheimer's disease

    Claire Lafay-Chebassier;Marc Paccalin;Guylène Page;Stéphanie Barc-Pain

  • Increased hypoxic tolerance by chemical inhibition of oxidative phosphorylation: "chemical preconditioning".

    M W Riepe;F Esclaire;K Kasischke;S Schreiber

  • mTOR-dependent signalling in Alzheimer's disease.

    Jin-Jing Pei;Jacques Hugon

  • Long COVID: cognitive complaints (brain fog) and dysfunction of the cingulate cortex.

    Jacques Hugon;Eva-Flore Msika;Mathieu Queneau;Karim Farid

  • The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer’s disease

    Annika Öhrfelt;Ann Brinkmalm;Julien Dumurgier;Gunnar Brinkmalm

  • Involvement of double‐stranded RNA‐dependent protein kinase and phosphorylation of eukaryotic initiation factor‐2α in neuronal degeneration

    Raymond Chuen Chung Chang;Ka Chun Suen;Chi Him Ma;Wassim Elyaman

  • Contribution to Alzheimer's disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls.

    Céline Bellenguez;Céline Bellenguez;Céline Bellenguez;Camille Charbonnier;Benjamin Grenier-Boley;Benjamin Grenier-Boley;Benjamin Grenier-Boley;Olivier Quenez

  • Tick‐bite meningoradiculoneuritis Clinical, electrophysiologic, and histologic findings in 10 cases

    J. M. Vallat;J. Hugon;M. Lubeau;M. J. Leboutet

  • Tyk2/STAT3 Signaling Mediates β-Amyloid-Induced Neuronal Cell Death: Implications in Alzheimer's Disease

    Jun Wan;Amy K.Y. Fu;Fanny C.F. Ip;Ho Keung Ng

  • Studies on the aetiology and pathogenesis of motor neuron diseases: 1. Lathyrism: Clinical findings in established cases

    A. C. Ludolph;A. C. Ludolph;J. Hugon;M. P. Dwived;M. P. Dwived;H. H. Schaumburg

  • Activated double-stranded RNA-dependent protein kinase and neuronal death in models of Alzheimer's disease.

    G. Page;A. Rioux Bilan;S. Ingrand;C. Lafay-Chebassier

  • Cerebrospinal fluid amyloid-β 42/40 ratio in clinical setting of memory centers: a multicentric study

    Julien Dumurgier;Susanna Schraen;Audrey Gabelle;Olivier Vercruysse

  • Hepatitis C Virus Controls Interferon Production through PKR Activation

    Noëlla Arnaud;Stéphanie Dabo;Patrick Maillard;Agata Budkowska

  • Donepezil decreases annual rate of hippocampal atrophy in suspected prodromal Alzheimer's disease

    Bruno Dubois;Bruno Dubois;Marie Chupin;Harald Hampel;Harald Hampel;Simone Lista

  • Activated mTOR and PKR kinases in lymphocytes correlate with memory and cognitive decline in Alzheimer's disease.

    Marc Paccalin;Stéphanie Pain-Barc;Claudette Pluchon;Chloé Paul

Frequent Co-Authors

Florence Pasquier
Florence Pasquier University of Lille
Kaj Blennow
Kaj Blennow University of Gothenburg
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg
Frédéric Blanc
Frédéric Blanc University of Strasbourg
Didier Hannequin
Didier Hannequin Grenoble Alpes University
Kina Höglund
Kina Höglund Sahlgrenska University Hospital
Kwok-Fai So
Kwok-Fai So University of Hong Kong
Constantin Bouras
Constantin Bouras University of Geneva

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