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Genetics
France
2024

D-Index & Metrics

Genetics

D-Index
84
Citations
39831
World Ranking
1342
National Ranking
47

Medicine

D-Index
90
Citations
43177
World Ranking
11992
National Ranking
373

Research.com Recognitions

  • 2024 - Research.com Genetics in France Leader Award

Overview

Didier Hannequin is affiliated with Grenoble Alpes University in France and has contributed extensively to research in medicine, with a particular focus on neurology and genetic aspects of neurological diseases. The scientist's body of work includes 28 publications in medicine and 16 in biochemistry, genetics, and molecular biology. Their research spans several subfields including neurology, physiology, genetics, molecular biology, and psychiatry and mental health.

The main research topics covered by Didier Hannequin include:

  • Alzheimer's disease research and treatments
  • Neurological diseases and metabolism
  • Parkinson's disease mechanisms and treatments
  • Dementia and cognitive impairment research
  • Amyotrophic lateral sclerosis research
  • Genomic variations and chromosomal abnormalities
  • Statistical methods in clinical trials

Recent scientific papers by Didier Hannequin reflect involvement in clinical and genetic studies related to neurological disorders and dementia. Notable recent works include:

  • "A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease," 2021, published in Nature Medicine
  • "Clinical and genetic spectra of 1550 index patients with hereditary spastic paraplegia," 2021, published in Brain
  • "Plasma NfL levels and longitudinal change rates in C9orf72 and GRN-associated diseases: from tailored references to clinical applications," 2021, published in Journal of Neurology Neurosurgery & Psychiatry
  • "Primary Progressive Aphasia Associated With GRN Mutations," 2021, published in Neurology
  • "Plasma progranulin levels for frontotemporal dementia in clinical practice: a 10-year French experience," 2020, published in Neurobiology of Aging

In terms of frequent publication venues, Didier Hannequin has contributed multiple articles to:

  • Alzheimer's & Dementia
  • Neurology
  • Biological Psychiatry
  • Journal of Neurology Neurosurgery & Psychiatry
  • Genetics in Medicine

Collaboration is a significant aspect of Didier Hannequin's research environment. Frequent co-authors in the scientist's publications include:

  • David Wallon
  • Florence Pasquier
  • Jérémie Pariente
  • Alexis Brice
  • Isabelle Le Ber

This diverse network of co-authors, along with publications across several high-impact journals, suggests an active engagement in research collaborations centered on neurodegenerative disease mechanisms and genetic contributions to neurological conditions.

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Genome-wide association study indentifies variants at CLU and CR1 associated with Alzheimer’s disease

    J Lambert;S Heath;G Even;D Campion

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

    Anne Rovelet-Lecrux;Didier Hannequin;Gregory Raux;Nathalie Le Meur

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Early-Onset Autosomal Dominant Alzheimer Disease: Prevalence, Genetic Heterogeneity, and Mutation Spectrum

    Dominique Campion;Cécile Dumanchin;Didier Hannequin;Bruno Dubois

  • APOE and Alzheimer disease: a major gene with semi-dominant inheritance

    E Genin;D Hannequin;D Wallon;K Sleegers

  • APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases

    Hélène-Marie Lanoiselée;Gaël Nicolas;David Wallon;Anne Rovelet-Lecrux

  • Frontotemporal dementia and its subtypes: a genome-wide association study

    Raffaele Ferrari;Raffaele Ferrari;Dena G Hernandez;Dena G Hernandez;Michael A Nalls;Jonathan D Rohrer

  • A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk

    Ute Dreses-Werringloer;Jean Charles Lambert;Valérie Vingtdeux;Haitian Zhao

  • Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice

    Annika Keller;Annika Keller;Annika Keller;Ana Westenberger;Maria J Sobrido;Maria García-Murias

  • Mutations of the presenilin I gene in families with early-onset Alzheimer's disease.

    Dominique Campion;Dominique Campion;Jean-Michel Flaman;Alexis Brice;Didier Hannequin

  • Phenotype variability in progranulin mutation carriers: a clinical, neuropsychological, imaging and genetic study

    Isabelle Le Ber;Agnès Camuzat;Didier Hannequin;Florence Pasquier

  • TARDBP mutations in motoneuron disease with frontotemporal lobar degeneration

    Lina Benajiba;Isabelle Le Ber;Agnès Camuzat;Mathieu Lacoste

  • SOD1, ANG, VAPB, TARDBP, and FUS mutations in familial amyotrophic lateral sclerosis: genotype–phenotype correlations

    Stéphanie Millecamps;François Salachas;Cécile Cazeneuve;Paul H. Gordon

  • Dissociating atrophy and hypometabolism impact on episodic memory in mild cognitive impairment.

    Gaël Chetelat;Béatrice Desgranges;Vincent de la Sayette;Fausto Viader

  • Segregation of a Missense Mutation in the Microtubule-Associated Protein Tau Gene with Familial Frontotemporal Dementia and Parkinsonism

    Cécile Dumanchin;Agnès Camuzat;Dominique Campion;Patrice Verpillat

  • Phenotype associated with APP duplication in five families

    Lucie Cabrejo;Lucie Guyant-Maréchal;Annie Laquerrière;Martine Vercelletto

Frequent Co-Authors

Dominique Campion
Dominique Campion University of Rouen
Florence Pasquier
Florence Pasquier University of Lille
Alexis Brice
Alexis Brice Institut du Cerveau
Thierry Frebourg
Thierry Frebourg Grenoble Alpes University
Bruno Dubois
Bruno Dubois Université Paris Cité
Benjamin Grenier-Boley
Benjamin Grenier-Boley Institut Pasteur
Vincent Chouraki
Vincent Chouraki University of Lille
Yves Agid
Yves Agid Institut du Cerveau

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