D-Index & Metrics Best Publications
Vincent Chouraki

Vincent Chouraki

Institut Pasteur
France

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • Internal medicine

His scientific interests lie mostly in Genetics, Genome-wide association study, Single-nucleotide polymorphism, Alzheimer's disease and PICALM. His Genetics study integrates concerns from other disciplines, such as Internal medicine and Disease. In general Disease, his work in Disease susceptibility is often linked to CD33 and ABCA7 linking many areas of study.

Vincent Chouraki works mostly in the field of Genome-wide association study, limiting it down to topics relating to Genetic association and, in certain cases, Apolipoprotein E, Age of onset, Heritability, Polymorphism and Cohort. His Alzheimer's disease research incorporates themes from Molecular genetics, Dementia, Case-control study and Late onset. The study of PICALM is intertwined with the study of SORL1 in a number of ways.

His most cited work include:

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease (2614 citations)
  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease (2614 citations)
  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease (2614 citations)

What are the main themes of his work throughout his whole career to date?

Vincent Chouraki spends much of his time researching Genome-wide association study, Genetics, Disease, Genetic association and Internal medicine. His Genome-wide association study research is multidisciplinary, relying on both Alzheimer's disease, Allele frequency, SNP and Locus. Genetics is closely attributed to Apolipoprotein E in his research.

Vincent Chouraki interconnects Meta-analysis, Neuroscience, Polymorphism and Bioinformatics in the investigation of issues within Disease. His Single-nucleotide polymorphism research focuses on subjects like Genetic predisposition, which are linked to Case-control study. As a member of one scientific family, Vincent Chouraki mostly works in the field of PICALM, focusing on SORL1 and, on occasion, Candidate gene, Susceptibility locus and Disease susceptibility.

He most often published in these fields:

  • Genome-wide association study (109.84%)
  • Genetics (104.10%)
  • Disease (57.38%)

What were the highlights of his more recent work (between 2016-2021)?

  • Genome-wide association study (109.84%)
  • Genetics (104.10%)
  • Dementia (23.77%)

In recent papers he was focusing on the following fields of study:

Vincent Chouraki mainly focuses on Genome-wide association study, Genetics, Dementia, Internal medicine and Disease. His Genome-wide association study research is multidisciplinary, incorporating elements of Apolipoprotein E, Computational biology, Genetic association and Locus. In his research on the topic of Genetic association, PSEN2 is strongly related with Endophenotype.

His research is interdisciplinary, bridging the disciplines of Alzheimer's disease and Genetics. His Dementia research integrates issues from Endocrinology, Cohort study, High-density lipoprotein and Lipoprotein. The study incorporates disciplines such as Meta-analysis, Neuroimaging and Physical medicine and rehabilitation in addition to Disease.

Between 2016 and 2021, his most popular works were:

  • Analysis of shared heritability in common disorders of the brain (726 citations)
  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease (429 citations)
  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease (429 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Genetics

His scientific interests lie mostly in Genome-wide association study, Genetics, Alzheimer's disease, Locus and Allele frequency. His work carried out in the field of Genome-wide association study brings together such families of science as Cohort study, Genetic association, Apolipoprotein E, Risk factor and Comorbidity. His studies in Genetic association integrate themes in fields like Genetic heterogeneity, Clinical psychology and Heritability.

Vincent Chouraki combines subjects such as Dentate gyrus, Hippocampal formation, Subiculum and Episodic memory with his study of Locus. In the subject of general Allele frequency, his work in Minor allele frequency is often linked to TREM2, thereby combining diverse domains of study. His Case-control study research focuses on Linkage disequilibrium and how it connects with Immunology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj.
Nature Genetics (2013)

3630 Citations

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish.
Nature Genetics (2011)

1904 Citations

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi.
PLOS ONE (2014)

1380 Citations

Analysis of shared heritability in common disorders of the brain

Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters.
Science (2018)

1200 Citations

Incidence of Dementia over Three Decades in the Framingham Heart Study

Claudia L. Satizabal;Alexa S. Beiser;Vincent Chouraki;Geneviève Chêne.
The New England Journal of Medicine (2016)

965 Citations

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez.
Nature Genetics (2017)

683 Citations

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu.
Nature Communications (2016)

388 Citations

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

G. Davies;N. Armstrong;J. C. Bis;J. Bressler.
(2015)

381 Citations

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

Kuan Lin Huang;Edoardo Marcora;Anna A. Pimenova;Antonio F. Di Narzo.
Nature Neuroscience (2017)

270 Citations

Common variants at 12q14 and 12q24 are associated with hippocampal volume

Joshua C Bis;Charles DeCarli;Albert Vernon Smith;Fedde van der Lijn.
Nature Genetics (2012)

252 Citations

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