Sheila S. David

Research.com Recognitions

• 2011 - Fellow of the American Chemical Society
• 2010 - Fellow of the American Association for the Advancement of Science (AAAS)
• 1998 - Fellow of Alfred P. Sloan Foundation

Overview

Best Publications

• Base-excision repair of oxidative DNA damage

  Sheila S. David;Valerie L. O'Shea;Sucharita Kundu

  1465
  Citations

• Chemistry of Glycosylases and Endonucleases Involved in Base-Excision Repair

  Sheila S. David;Scott D. Williams

  616
  Citations

• DNA-mediated charge transport for DNA repair

  Elizabeth M. Boon;Alison L. Livingston;Nikolas H. Chmiel;Sheila S. David

  294
  Citations

• Single-turnover and pre-steady-state kinetics of the reaction of the adenine glycosylase MutY with mismatch-containing DNA substrates.

  Silvia L. Porello;and Aquiles E. Leyes;Sheila S. David

  242
  Citations

• DNA-Bound Redox Activity of DNA Repair Glycosylases Containing [4Fe-4S] Clusters†

  Amie K. Boal;Eylon Yavin;Olga A. Lukianova;Valerie L. O'Shea

  221
  Citations

• RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1

  Jongchan Yeo;Rena A. Goodman;Nicole T. Schirle;Sheila S. David

  196
  Citations

• Protein–DNA charge transport: Redox activation of a DNA repair protein by guanine radical

  Eylon Yavin;Amie K. Boal;Eric D. A. Stemp;Elizabeth M. Boon

  172
  Citations

• Removal of hydantoin products of 8-oxoguanine oxidation by the Escherichia coli DNA repair enzyme, FPG.

  Michael D. Leipold;James G. Muller;Cynthia J. Burrows;Sheila S. David

  170
  Citations

• A role for iron-sulfur clusters in DNA repair.

  Olga A Lukianova;Sheila S David

  168
  Citations

• Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1.

  Nirmala Krishnamurthy;Xiaobei Zhao;Cynthia J. Burrows;Sheila S. David

  159
  Citations

• A Substrate Recognition Role for the [4Fe-4S]2+ Cluster of the DNA Repair Glycosylase MutY†

  Silvia L. Porello;Michelle J. Cannon;Sheila S. David

  150
  Citations

• Insight into the Functional Consequences of Inherited Variants of the hMYH Adenine Glycosylase Associated with Colorectal Cancer: Complementation Assays with hMYH Variants and Pre-steady-state Kinetics of the Corresponding Mutated E. coli Enzymes

  Nikolas H Chmiel;Alison L Livingston;Sheila S David

  129
  Citations

• Specific Recognition of Substrate Analogs by the DNA Mismatch Repair Enzyme MutY

  Silvia L. Porello;Scott D. Williams;Heiko Kuhn;Mark L. Michaels

  115
  Citations

• Efficient recognition of substrates and substrate analogs by the adenine glycosylase MutY requires the C-terminal domain

  Nikolas H. Chmiel;Marie Pierre Golinelli;Anthony W. Francis;Sheila S. David

  113
  Citations

• Magnetization and electron paramagnetic resonance studies of reduced uteroferrin and its "EPR-silent" phosphate complex.

  E. P. Day;S. S. David;J. Peterson;W. R. Dunham

  105
  Citations

• Anion binding to uteroferrin. Evidence for phosphate coordination to the iron(III) ion of the dinuclear active site and interaction with the hydroxo bridge

  Sheila S. David;Lawrence Que

  104
  Citations

• Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts.

  Xiaobei Zhao;Nirmala Krishnamurthy;Cynthia J. Burrows;Sheila S. David

  103
  Citations

• Recognition and removal of oxidized guanines in duplex DNA by the base excision repair enzymes hOGG1, yOGG1, and yOGG2.

  Michael D. Leipold;Hillary Workman;James G. Muller;Cynthia J. Burrows

  102
  Citations

• Evidence that MutY is a monofunctional glycosylase capable of forming a covalent Schiff base intermediate with substrate DNA

  Scott D. Williams;Sheila S. David

  101
  Citations

• NMR evidence for specific intercalation of .DELTA.-rh(phen)2.phi.3+ in [d(GTCGAC)2]

  Sheila S. David;Jacqueline K. Barton

  99
  Citations

• Structure and potential mutagenicity of new hydantoin products from guanosine and 8-oxo-7,8-dihydroguanine oxidation by transition metals.

  Cynthia J Burrows;James G Muller;Olga Kornyushyna;Wenchen Luo

  97
  Citations