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Molecular Biology

D-Index
89
Citations
25211
World Ranking
763
National Ranking
404

Overview

Bennett Van Houten is affiliated with the University of Pittsburgh in the United States. Their research primarily falls within Biochemistry, Genetics and Molecular Biology, with a total of 107 publications in the field. The subfields of study include Molecular Biology, Oncology, Cancer Research, Cell Biology, and Genetics.

Their work covers a wide array of topics, including:

  • DNA Repair Mechanisms
  • DNA and Nucleic Acid Chemistry
  • Genomics and Chromatin Dynamics
  • Advanced biosensing and bioanalysis techniques
  • CRISPR and Genetic Engineering
  • Epigenetics and DNA Methylation
  • RNA Interference and Gene Delivery

Recent publications demonstrate active engagement with research on DNA repair and cellular mechanisms. Noteworthy papers include:

  • "Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles," 2021, Nature Aging
  • "The involvement of nucleotide excision repair proteins in the removal of oxidative DNA damage," 2020, Nucleic Acids Research
  • "Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening," 2022, Nature Structural & Molecular Biology
  • "PARP1: Structural insights and pharmacological targets for inhibition," 2021, DNA repair
  • "Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins," 2022, Nature Communications

The main publication venues for their research include:

  • DNA repair
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • UNC Libraries

Bennett Van Houten often collaborates with several researchers, with frequent co-authors including:

  • Matthew A. Schaich
  • Vera Roginskaya
  • Brittani L Schnable
  • Namrata Kumar
  • Sripriya Raja

Best Publications

  • Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

    F. Michael Yakes;Bennett Van Houten

  • Adipose tissue and adipocytes support tumorigenesis and metastasis.

    Kristin M. Nieman;Iris L. Romero;Bennett Van Houten;Ernst Lengyel

  • Energy metabolism in human pluripotent stem cells and their differentiated counterparts.

    Sandra Varum;Ana S. B. Rodrigues;Michelle B. Moura;Olga Momcilovic

  • Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.

    Eugenia Trushina;Roy B. Dyer;John D. Badger;Daren Ure

  • Standardizing global gene expression analysis between laboratories and across platforms

    Theodore Bammler;Richard P. Beyer;Sanchita Bhattacharya;Gary A. Boorman

  • Hydrogen Peroxide– and Peroxynitrite-Induced Mitochondrial DNA Damage and Dysfunction in Vascular Endothelial and Smooth Muscle Cells

    Scott W. Ballinger;Cam Patterson;Chang Ning Yan;Richard Doan

  • Role of mitochondrial DNA in toxic responses to oxidative stress

    Bennett Van Houten;Victoria Woshner;Janine H. Santos

  • Mitochondrial DNA repair and aging.

    Bhaskar S Mandavilli;Janine H Santos;Bennett Van Houten

  • Role of mitochondria in toxic oxidative stress.

    Marc W. Fariss;Catherine B. Chan;Manisha Patel;Bennett Van Houten

  • Prokaryotic nucleotide excision repair: the UvrABC system.

    James J. Truglio;Deborah L. Croteau;Bennett Van Houten;Caroline Kisker

  • Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells.

    Amy Furda;Janine H. Santos;Joel N. Meyer;Bennett Van Houten

  • Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage.

    Janine Hertzog Santos;Joel N. Meyer;Milan Skorvaga;Lois A. Annab

  • High-Mobility Group Box 1 Is Essential for Mitochondrial Quality Control

    Daolin Tang;Rui Kang;Kristen M. Livesey;Guido Kroemer

  • Mitochondrial dysfunction in neurodegenerative diseases and cancer.

    Michelle Barbi de Moura;Lucas Santana dos Santos;Bennett Van Houten

  • Mitochondria, energetics, epigenetics, and cellular responses to stress.

    Daniel T. Shaughnessy;Kimberly McAllister;Leroy Worth;Astrid C. Haugen

  • Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species.

    Eun-Ryeong Hahm;Michelle B. Moura;Eric E. Kelley;Bennett Van Houten

  • Integrating phenotypic and expression profiles to map arsenic-response networks

    Astrid C Haugen;Ryan Kelley;Jennifer B Collins;Charles J Tucker

  • Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair

    Deniz Simsek;Deniz Simsek;Amy Furda;Yankun Gao;Jérôme Artus

  • Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death

    Janine Hertzog Santos;L'uba Hunakova;Yiming Chen;Carl Bortner

  • Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis

    Janine Hertzog Santos;Joel N. Meyer;Bennett Van Houten

Frequent Co-Authors

Caroline Kisker
Caroline Kisker University of Würzburg
Deborah L. Croteau
Deborah L. Croteau National Institutes of Health
Joel N. Meyer
Joel N. Meyer Duke University
Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Peter Wipf
Peter Wipf University of Pittsburgh
Robert W. Sobol
Robert W. Sobol University of South Alabama
Nicholas E. Geacintov
Nicholas E. Geacintov New York University
Samuel H. Wilson
Samuel H. Wilson National Institutes of Health
Jerry Vockley
Jerry Vockley University of Pittsburgh
Donna B. Stolz
Donna B. Stolz University of Pittsburgh

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