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D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
15047
World Ranking
10162
National Ranking
734

Overview

Caroline Kisker is affiliated with the University of Würzburg in Germany and specializes in Biochemistry, Genetics, and Molecular Biology with a primary focus on Molecular Biology. Their research covers several interrelated subfields including Oncology, Cell Biology, Genetics, and Organic Chemistry.

Their main research topics encompass:

  • DNA Repair Mechanisms
  • DNA and Nucleic Acid Chemistry
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • CRISPR and Genetic Engineering
  • Ubiquitin and proteasome pathways
  • Cancer-related Molecular Pathways

Among the recent papers associated with Caroline Kisker are:

  • Computed structures of core eukaryotic protein complexes, 2021, Science
  • Global discovery of bacterial RNA-binding proteins by RNase-sensitive gradient profiles reports a new FinO domain protein, 2020, RNA
  • Structural basis for CDK7 activation by MAT1 and Cyclin H, 2020, Proceedings of the National Academy of Sciences
  • In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair, 2020, Nature Communications
  • The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair, 2020, Nucleic Acids Research

Frequent co-authors in this body of work include:

  • Jochen Kuper
  • Florian Sauer
  • W. Koelmel
  • Stefan Peissert
  • Andreas Schlösser

Publications are often situated in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Nature Communications
  • Free Radical Biology and Medicine
  • Science

Best Publications

  • Structure of ADP x AIF4(-)-stabilized nitrogenase complex and its implications for signal transduction.

    Hermann Schindelin;Caroline Kisker;Jamie L. Schlessman;James B. Howard

  • Molybdenum-Cofactor–Containing Enzymes: Structure and Mechanism

    Caroline Kisker;Hermann Schindelin;Douglas C. Rees

  • Molecular basis of sulfite oxidase deficiency from the structure of sulfite oxidase.

    Caroline Kisker;Hermann Schindelin;Andrew Pacheco;William A Wehbi

  • Crystal structure of DMSO reductase: redox-linked changes in molybdopterin coordination.

    Hermann Schindelin;Caroline Kisker;James Hilton;K. V. Rajagopalan

  • Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance

    Winfried Hinrichs;Caroline Kisker;Martina Düvel;Alexander Müller

  • Computed structures of core eukaryotic protein complexes.

    Ian R. Humphreys;Jimin Pei;Minkyung Baek;Aditya Krishnakumar

  • Constitutive Activation of PKA Catalytic Subunit in Adrenal Cushing's Syndrome

    Felix Beuschlein;Martin Fassnacht;Guillaume Assié;Davide Calebiro

  • Prokaryotic nucleotide excision repair: the UvrABC system.

    James J. Truglio;Deborah L. Croteau;Bennett Van Houten;Caroline Kisker

  • Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis.

    Caixia Guo;Paula L. Fischhaber;Margaret J. Luk-Paszyc;Yuji Masuda

  • Crystal structure of dimethyl sulfoxide reductase from Rhodobacter capsulatus at 1.88 A resolution.

    Frank Schneider;Jan Löwe;Robert Huber;Hermann Schindelin

  • A left-hand beta-helix revealed by the crystal structure of a carbonic anhydrase from the archaeon Methanosarcina thermophila.

    Caroline Kisker;Hermann Schindelin;Birgit E. Alber;James G. Ferry

  • High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains of Mycobacterium tuberculosis

    Todd J. Sullivan;James J. Truglio;James J. Truglio;Melissa E. Boyne;Polina Novichenok

  • The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance.

    Caroline Kisker;Winfried Hinrichs;Karlheinz Tovar;Wolfganf Hillen

  • Structural basis and mechanism of enoyl reductase inhibition by triclosan.

    Michael J Stewart;Sapan Parikh;Guoping Xiao;Peter J Tonge

  • Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus

    James J Truglio;Karsten Theis;Silke Leimkühler;Roberto Rappa

  • Crystal Structure of the FeS Cluster–Containing Nucleotide Excision Repair Helicase XPD

    Stefanie C Wolski;Jochen Kuper;Petra Hänzelmann;James J Truglio

  • A slow, tight binding inhibitor of InhA, the enoyl-acyl carrier protein reductase from Mycobacterium tuberculosis.

    Sylvia R. Luckner;Nina Liu;Christopher W. am Ende;Peter J. Tonge

  • A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila.

    Tina M. Iverson;Birgit E. Alber;Caroline Kisker;James G. Ferry

  • Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair.

    Karsten Theis;Paul J. Chen;Milan Skorvaga;Milan Skorvaga;Bennett Van Houten

  • Crystal Structure and Deletion Analysis Show that the Accessory Subunit of Mammalian DNA Polymerase γ, PolγB, Functions as a Homodimer

    José A. Carrodeguas;Karsten Theis;Daniel F. Bogenhagen;Caroline Kisker

Frequent Co-Authors

Peter J. Tonge
Peter J. Tonge Stony Brook University
Hermann Schindelin
Hermann Schindelin University of Würzburg
Bennett Van Houten
Bennett Van Houten University of Pittsburgh
Christoph A. Sotriffer
Christoph A. Sotriffer University of Würzburg
Douglas C. Rees
Douglas C. Rees California Institute of Technology
Deborah L. Croteau
Deborah L. Croteau National Institutes of Health
Wolfram Saenger
Wolfram Saenger Freie Universität Berlin
K. V. Rajagopalan
K. V. Rajagopalan Duke University
Martin J. Mueller
Martin J. Mueller University of Würzburg
Martin Fassnacht
Martin Fassnacht University of Würzburg

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