2019 - Fellow of the American Association for the Advancement of Science (AAAS)
2001 - Fellow of Alfred P. Sloan Foundation
Peter J. Tonge brings together Nuclear medicine and Positron emission tomography to produce work in his papers. Peter J. Tonge undertakes interdisciplinary study in the fields of Positron emission tomography and Nuclear medicine through his research. In his works, he conducts interdisciplinary research on Mycobacterium tuberculosis and Tuberculosis. Peter J. Tonge carries out multidisciplinary research, doing studies in Tuberculosis and Mycobacterium tuberculosis. His Isoniazid study frequently involves adjacent topics like Pathology. His Pathology study frequently links to adjacent areas such as Isoniazid. Peter J. Tonge connects Pharmacology with Biotechnology in his research. His research is interdisciplinary, bridging the disciplines of In vivo and Biotechnology. He performs multidisciplinary study in In vivo and Pharmacokinetics in his work.
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Drug–target residence time: critical information for lead optimization
Hao Lu;Peter J Tonge.
Current Opinion in Chemical Biology (2010)
The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistance.
Richa Rawat;Adrian Whitty;Peter J. Tonge.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Drug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosis.
Sarah L. Kinnings;Nina Liu;Nancy Buchmeier;Peter J. Tonge.
PLOS Computational Biology (2009)
Inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis, by triclosan and isoniazid.
Sapan L. Parikh;Guoping Xiao;Peter J. Tonge.
High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains of Mycobacterium tuberculosis
Todd J. Sullivan;James J. Truglio;James J. Truglio;Melissa E. Boyne;Polina Novichenok.
ACS Chemical Biology (2006)
Structural basis and mechanism of enoyl reductase inhibition by triclosan.
Michael J Stewart;Sapan Parikh;Guoping Xiao;Peter J Tonge.
Journal of Molecular Biology (1999)
Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathway.
Hao Lu;Peter J. Tonge.
Accounts of Chemical Research (2008)
Observation of excited-state proton transfer in green fluorescent protein using ultrafast vibrational spectroscopy.
Deborah Stoner-Ma;Andrew A. Jaye;Pavel Matousek;Michael Towrie.
Journal of the American Chemical Society (2005)
Probing the ground state structure of the green fluorescent protein chromophore using Raman spectroscopy.
Alasdair F. Bell;Xiang He;Rebekka M. Wachter;Peter J. Tonge.
A slow, tight binding inhibitor of InhA, the enoyl-acyl carrier protein reductase from Mycobacterium tuberculosis.
Sylvia R. Luckner;Nina Liu;Christopher W. am Ende;Peter J. Tonge.
Journal of Biological Chemistry (2010)
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