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Molecular Biology

D-Index
67
Citations
21181
World Ranking
1555
National Ranking
127

Overview

Kiyotaka Okada is affiliated with the National Institute for Basic Biology in Japan. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with a notable focus on molecular and cellular mechanisms related to bone metabolism and extracellular vesicles.

Their work extensively covers several main topics, including:

  • Extracellular vesicles in disease
  • Bone and Joint Diseases
  • MicroRNA in disease regulation
  • Protease and Inhibitor Mechanisms
  • Bone Metabolism and Diseases
  • Bone health and treatments
  • Plant Molecular Biology Research

Okada has contributed to various publication venues, with multiple papers published in:

  • PLoS ONE
  • Calcified Tissue International
  • Bone
  • International Journal of Molecular Sciences
  • Endocrine Journal

Frequent collaborators in Okada's research include Hiroshi Kaji, Naoyuki Kawao, Yoshimasa Takafuji, Takashi Ohira, and Yuya Mizukami. These coauthors have contributed to numerous studies together, reflecting ongoing research partnerships.

Representative publications authored or co-authored by Okada include:

  • PAI-1 is involved in delayed bone repair induced by glucocorticoids in mice (2020, Bone)
  • Extracellular vesicles secreted from mouse muscle cells suppress osteoclast formation: Roles of mitochondrial energy metabolism (2020, Bone)
  • MicroRNA-196a-5p in Extracellular Vesicles Secreted from Myoblasts Suppresses Osteoclast-like Cell Formation in Mouse Cells (2020, Calcified Tissue International)
  • Extracellular vesicles secreted from mouse muscle cells improve delayed bone repair in diabetic mice (2022, Endocrine Journal)
  • Effects of fluid flow shear stress to mouse muscle cells on the bone actions of muscle cell-derived extracellular vesicles (2021, PLoS ONE)

Their research often highlights the biological functions and therapeutic potential of extracellular vesicles derived from muscle cells in the context of bone diseases and repair mechanisms.

Okada's subfields of study are diverse, including Molecular Biology, Cancer Research, Orthopedics and Sports Medicine, Plant Science, and Hematology. This multidisciplinary approach underscores a broad interest across biomedical research areas, particularly with mechanistic insights into cellular communication and regulation relevant to bone physiology and pathologies.

Best Publications

  • Requirement of the Auxin Polar Transport System in Early Stages of Arabidopsis Floral Bud Formation.

    Kiyotaka Okada;Junichi Ueda;Masako K. Komaki;Callum J. Bell

  • The DEFECTIVE IN ANTHER DEHISCENCE1 Gene Encodes a Novel Phospholipase A1 Catalyzing the Initial Step of Jasmonic Acid Biosynthesis, Which Synchronizes Pollen Maturation, Anther Dehiscence, and Flower Opening in Arabidopsis

    Sumie Ishiguro;Akiko Kawai-Oda;Junichi Ueda;Ikuo Nishida

  • Arabidopsis nph1 and npl1: Blue light receptors that mediate both phototropism and chloroplast relocation

    Tatsuya Sakai;Takatoshi Kagawa;Masahiro Kasahara;Trevor E. Swartz

  • Arabidopsis NPL1: a phototropin homolog controlling the chloroplast high-light avoidance response.

    Takatoshi Kagawa;Tatsuya Sakai;Noriyuki Suetsugu;Kazusato Oikawa

  • Molecular interaction between COP1 and HY5 defines a regulatory switch for light control of Arabidopsis development

    Lay-Hong Ang;Sudip Chattopadhyay;Ning Wei;Tokitaka Oyama

  • Epidermal cell differentiation in Arabidopsis determined by a Myb homolog, CPC

    Takuji Wada;Tatsuhiko Tachibana;Tatsuhiko Tachibana;Yoshiro Shimura;Yoshiro Shimura;Kiyotaka Okada;Kiyotaka Okada

  • TRIPTYCHON and CAPRICE mediate lateral inhibition during trichome and root hair patterning in Arabidopsis

    S. Schellmann;S. Schellmann;A. Schnittger;A. Schnittger;V. Kirik;V. Kirik;T. Wada

  • FILAMENTOUS FLOWER, a meristem and organ identity gene of Arabidopsis, encodes a protein with a zinc finger and HMG-related domains

    Shinichiro Sawa;Keiro Watanabe;Koji Goto;Eiko Kanaya

  • HY5 stability and activity in Arabidopsis is regulated by phosphorylation in its COP1 binding domain

    Christian S. Hardtke;Kazuhito Gohda;Mark T. Osterlund;Tokitaka Oyama;Tokitaka Oyama

  • The Phototropin Family of Photoreceptors

    W.R. Briggs;C.F. Beck;A.R. Cashmore;J.M. Christie

  • Reversible root tip rotation in Arabidopsis seedlings induced by obstacle-touching stimulus.

    Kiyotaka Okada;Yoshiro Shimura

  • Role of a positive regulator of root hair development, CAPRICE ,in Arabidopsis root epidermal cell differentiation

    Takuji Wada;Tetsuya Kurata;Rumi Tominaga;Yoshihiro Koshino-Kimura

  • Roles of the Middle Domain–Specific WUSCHEL-RELATED HOMEOBOX Genes in Early Development of Leaves in Arabidopsis

    Miyuki Nakata;Miyuki Nakata;Noritaka Matsumoto;Ryuji Tsugeki;Enno Rikirsch

  • RPT2: A Signal Transducer of the Phototropic Response in Arabidopsis

    Tatsuya Sakai;Takuji Wada;Sumie Ishiguro;Kiyotaka Okada

  • Arabidopsis TRANSPARENT TESTA GLABRA2 Is Directly Regulated by R2R3 MYB Transcription Factors and Is Involved in Regulation of GLABRA2 Transcription in Epidermal Differentiation

    Tetsuya Ishida;Sayoko Hattori;Ryosuke Sano;Kayoko Inoue

  • Attractive and repulsive interactions between female and male gametophytes in Arabidopsis pollen tube guidance.

    Kentaro K Shimizu;Kiyotaka Okada

  • A homeobox gene, PRESSED FLOWER, regulates lateral axis-dependent development of Arabidopsis flowers

    Noritaka Matsumoto;Kiyotaka Okada

  • Chlorophyll b and phycobilins in the common ancestor of cyanobacteria and chloroplasts.

    Akiko Tomitani;Kiyotaka Okada;Hideaki Miyashita;Hans C. P. Matthijs

  • Functional analysis of each blue light receptor, cry1, cry2, phot1, and phot2, by using combinatorial multiple mutants in Arabidopsis.

    Maki Ohgishi;Kensuke Saji;Kiyotaka Okada;Tatsuya Sakai

  • Efficient transformation of Arabidopsis thaliana : comparison of the efficiencies with various organs, plant ecotypes and Agrobacterium strains

    Kazuhito Akama;Hideaki Shiraishi;Shozo Ohta;Kenzo Nakamura

Frequent Co-Authors

Yoshiro Shimura
Yoshiro Shimura Kyoto University
Tatsuya Sakai
Tatsuya Sakai Niigata University
Kentaro Shimizu
Kentaro Shimizu University of Zurich
Toshiro Ito
Toshiro Ito Nara Institute of Science and Technology
Shinichiro Sawa
Shinichiro Sawa Kumamoto University
Mikio Nishimura
Mikio Nishimura National Institute for Basic Biology
Ayumi Tanaka
Ayumi Tanaka Hokkaido University
Tomohiko Kato
Tomohiko Kato Kazusa DNA Research Institute
Charles Auffray
Charles Auffray Centre national de la recherche scientifique, CNRS

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