What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Biochemistry, Gene, Genetics, Molecular biology and Catabolite repression.
His study in the fields of Repressor, Operon, Tetracycline and Regulatory sequence under the domain of Biochemistry overlaps with other disciplines such as Xylose isomerase.
Particularly relevant to TetR is his body of work in Repressor.
His work carried out in the field of Molecular biology brings together such families of science as Gene expression, lac operon and Glucose dehydrogenase.
When carried out as part of a general Catabolite repression research project, his work on CCPA is frequently linked to work in Fed-batch culture, therefore connecting diverse disciplines of study.
Wolfgang Hillen has researched Mutant in several fields, including Transfection and Effector.
His most cited work include:
- Transcriptional activation by tetracyclines in mammalian cells (2314 citations)
- Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity (831 citations)
- MECHANISMS UNDERLYING EXPRESSION OF TN10 ENCODED TETRACYCLINE RESISTANCE (457 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Biochemistry, Molecular biology, Repressor, TetR and Gene.
His research links Bacillus subtilis with Biochemistry.
Within one scientific family, Wolfgang Hillen focuses on topics pertaining to Plasmid under Molecular biology, and may sometimes address concerns connected to Molecular cloning.
His study in Repressor is interdisciplinary in nature, drawing from both Tetracycline, Peptide sequence, Tn10 and DNA.
His TetR research integrates issues from Regulation of gene expression, Cell biology, Mutant and Stereochemistry.
His Gene research is classified as research in Genetics.
He most often published in these fields:
- Biochemistry (41.89%)
- Molecular biology (32.08%)
- Repressor (30.19%)
What were the highlights of his more recent work (between 2003-2014)?
- TetR (29.81%)
- Biochemistry (41.89%)
- Molecular biology (32.08%)
In recent papers he was focusing on the following fields of study:
TetR, Biochemistry, Molecular biology, Repressor and CCPA are his primary areas of study.
His TetR research is multidisciplinary, relying on both Effector, Cell biology, Mutant and Allosteric regulation.
His Biochemistry study combines topics from a wide range of disciplines, such as Stereochemistry and Bacillus subtilis.
His Molecular biology study integrates concerns from other disciplines, such as TET repressor, Reporter gene and Virulence.
The Repressor study combines topics in areas such as Tetracycline, Inducer and Protein–protein interaction.
His work in Catabolite repression tackles topics such as Transcriptional regulation which are related to areas like Operon.
Between 2003 and 2014, his most popular works were:
- A theophylline responsive riboswitch based on helix slipping controls gene expression in vivo (222 citations)
- In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice (193 citations)
- Structural Basis for Allosteric Control of the Transcription Regulator CcpA by the Phosphoprotein HPr-Ser46-P (138 citations)
In his most recent research, the most cited papers focused on:
Wolfgang Hillen focuses on Biochemistry, TetR, Mutant, CCPA and Catabolite repression.
His research on Biochemistry frequently connects to adjacent areas such as Biophysics.
As part of the same scientific family, Wolfgang Hillen usually focuses on TetR, concentrating on Regulation of gene expression and intersecting with Promoter and RNA.
His Mutant study combines topics in areas such as DNA, Gene silencing and Repressor.
His research in Repressor intersects with topics in Molecular biology, Regulator gene, Phosphoenolpyruvate carboxykinase and Virulence.
Gene and Transactivation is closely connected to Cell biology in his research, which is encompassed under the umbrella topic of Gene expression.
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