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Biology and Biochemistry

D-Index
45
Citations
5881
World Ranking
19172
National Ranking
1381

Overview

Masayuki Takahashi is affiliated with the Tokyo Institute of Technology in Japan. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with particular emphasis on Molecular Biology, Oncology, Plant Science, Pharmaceutical Science, and Genetics as subfields.

The scientist's work covers a range of topics, including:

  • DNA Repair Mechanisms
  • DNA and Nucleic Acid Chemistry
  • CRISPR and Genetic Engineering
  • RNA Interference and Gene Delivery
  • PARP inhibition in cancer therapy
  • Protein Structure and Dynamics
  • Bacterial Genetics and Biotechnology

Masayuki Takahashi has published extensively in various scientific journals. Frequent publication venues include:

  • International Journal of Molecular Sciences
  • Proceedings of the National Academy of Sciences
  • Nature Communications
  • eLife
  • Journal of Drug Delivery Science and Technology

Notable recent papers authored or co-authored by Takahashi include:

  • "Real-time tracking reveals catalytic roles for the two DNA binding sites of Rad51," 2020, Nature Communications
  • "A conserved Ctp1/CtIP C-terminal peptide stimulates Mre11 endonuclease activity," 2021, Proceedings of the National Academy of Sciences
  • "Two auxiliary factors promote Dmc1-driven DNA strand exchange via stepwise mechanisms," 2020, Proceedings of the National Academy of Sciences
  • "Cooperative interactions facilitate stimulation of Rad51 by the Swi5-Sfr1 auxiliary factor complex," 2020, eLife
  • "New biphasic system in side-by-side chambers for testing drug dissolution and permeation in vitro (BiDP system)," 2021, Journal of Drug Delivery Science and Technology

Masayuki Takahashi has collaborated with several frequent co-authors, including:

  • Kentaro Ito
  • Hiroshi Iwasaki
  • Shuji Kanamaru
  • Takahisa Maki
  • Tsutomu Mikawa

Best Publications

  • High yield purification and physico-chemical properties of full-length recombinant allelic variants of sheep prion protein linked to scrapie susceptibility.

    Human Rezaei;Daniel Marc;Yvan Choiset;Masayuki Takahashi

  • Kinetic and equilibrium characterization of the Tet repressor-tetracycline complex by fluorescence measurements: Evidence for divalent metal ion requirement and energy transfer

    Masayuki Takahashi;Lothar Altschmied;Wolfgang Hillen

  • Structural requirements of tetracycline-Tet repressor interaction: determination of equilibrium binding constants for tetracycline analogs with the Tet repressor.

    J Degenkolb;M Takahashi;G A Ellestad;W Hillen

  • DNA-binding parameters of the HU protein of Escherichia coli to cruciform DNA.

    Eliette Bonnefoy;Masayuki Takahashi;Josette Rouviere Yaniv

  • Differential binding of the Escherichia coli HU, homodimeric forms and heterodimeric form to linear, gapped and cruciform DNA.

    V Pinson;M Takahashi;J Rouviere-Yaniv

  • Tetracycline Analogs Affecting Binding to Tn10-Encoded Tet Repressor Trigger the Same Mechanism of Induction†

    Thomas Lederer;Martin Kintrup;Masayuki Takahashi;Phaik-Eng Sum

  • Ligand binding and physico-chemical properties of ASP2, a recombinant odorant-binding protein from honeybee (Apis mellifera L.).

    Loïc Briand;Claude Nespoulous;Jean-Claude Huet;Masayuki Takahashi

  • Rapid exchange of A:T base pairs is essential for recognition of DNA homology by human Rad51 recombination protein.

    Ravindra C. Gupta;Ewa Folta-Stogniew;Shawn O'Malley;Masayuki Takahashi

  • Binding stoichiometry and structure of RecA-DNA complexes studied by flow linear dichroism and fluorescence spectroscopy: Evidence for multiple heterogeneous DNA Co-ordination

    Masayuki Takahashi;Mikael Kubista;Bengt Nordén

  • DNA-induced partial unfolding of prion protein leads to its polymerisation to amyloid.

    P.K. Nandi;E. Leclerc;J.-C. Nicole;M. Takahashi

  • Hydrophobic catalysis and a potential biological role of DNA unstacking induced by environment effects

    Bobo Feng;Robert P Sosa;Anna K F Mårtensson;Kai Jiang

  • A Molecular Basis for the Selective Recognition of 2-Hydroxy-dATP and 8-Oxo-dGTP by Human MTH1

    Yasunari Sakai;Masato Furuichi;Masayuki Takahashi;Masaki Mishima

  • RecA tests homology at both pairing and strand exchange

    L R Bazemore;E Folta-Stogniew;M Takahashi;C M Radding

  • Ligand-modulated binding of a gene regulatory protein to DNA. Quantitative analysis of cyclic-AMP induced binding of CRP from Escherichia coli to non-specific and specific DNA targets.

    Masayuki Takahashi;Bernadette Blazy;Alain Baudras;Wolfgang Hillen

  • Real-time measurements of the nucleation, growth and dissociation of single Rad51–DNA nucleoprotein filaments

    Judith Miné;Ludovic Disseau;Masayuki Takahashi;Giovanni Cappello

  • Kinetic Analysis of Pairing and Strand Exchange Catalyzed by RecA: DETECTION BY FLUORESCENCE ENERGY TRANSFER *

    L. Rochelle Bazemore;Masayuki Takahashi;Charles M. Radding

  • Helicobacter pylori CagA causes mitotic impairment and induces chromosomal instability.

    Mayumi Umeda;Naoko Murata-Kamiya;Yasuhiro Saito;Yusuke Ohba

  • Structure of RecA-DNA complex and mechanism of DNA strand exchange reaction in homologous recombination

    Masayuki Takahashi;Bengt Nordén

  • Structure of human Rad51 protein filament from molecular modeling and site-specific linear dichroism spectroscopy

    Anna Reymer;Karolin Frykholm;Katsumi Morimatsu;Masayuki Takahashi

  • Structure of human MTH1, a nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates

    Masaki Mishima;Yasunari Sakai;Noriyuki Itoh;Hiroyuki Kamiya

Frequent Co-Authors

Bengt Nordén
Bengt Nordén Chalmers University of Technology
Hiroshi Iwasaki
Hiroshi Iwasaki Tokyo Institute of Technology
Mikael Kubista
Mikael Kubista Czech Academy of Sciences
Wolfgang Hillen
Wolfgang Hillen University of Erlangen-Nuremberg
Toshihiro Horii
Toshihiro Horii Osaka University
Kell Mortensen
Kell Mortensen University of Copenhagen
Hitoshi Kurumizaka
Hitoshi Kurumizaka University of Tokyo
Yusaku Nakabeppu
Yusaku Nakabeppu Kyushu University
mutsuo sekiguchi
mutsuo sekiguchi Fukuoka Dental College
Jean-Louis Viovy
Jean-Louis Viovy Institute Curie

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