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Takehiko Shibata

Takehiko Shibata

D-Index & Metrics

Molecular Biology

D-Index
67
Citations
12694
World Ranking
1589
National Ranking
134

Overview

Takehiko Shibata is a researcher affiliated with Yokohama City University in Japan. Their work primarily spans the field of Medicine, with a focus on Epidemiology, Infectious Diseases, Pulmonary and Respiratory Medicine, Molecular Biology, and Immunology.

The scientist's research centers on respiratory viral infections, neonatal respiratory health, pneumonia and respiratory infections, immune regulation, and related clinical studies on COVID-19 and SARS-CoV-2. Specific main research topics include:

  • Respiratory viral infections research
  • Neonatal Respiratory Health Research
  • Pneumonia and Respiratory Infections
  • Phagocytosis and Immune Regulation
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Asthma and respiratory diseases

Notable recent publications authored or co-authored by Takehiko Shibata include:

  • "Respiratory syncytial virus infection exacerbates pneumococcal pneumonia via Gas6/Axl-mediated macrophage polarization," 2020, Journal of Clinical Investigation
  • "The intrinsic ability of double-stranded DNA to carry out D-loop and R-loop formation," 2020, Computational and Structural Biotechnology Journal

The broader set of papers involving Shibata's research network includes collaborative works such as:

  • "RSV infection-elicited high MMP-12-producing macrophages exacerbate allergic airway inflammation with neutrophil infiltration," 2021, iScience
  • "Cationic-nanogel nasal vaccine containing the ectodomain of RSV-small hydrophobic protein induces protective immunity in rodents," 2023, npj Vaccines
  • "CpG ODN enhances the efficacy of F protein vaccine against respiratory syncytial virus infection in the upper respiratory tract via CD4+ T cells," 2023, Biochemical and Biophysical Research Communications

Frequent publication venues for Shibata's research include:

  • npj Vaccines
  • Journal of Clinical Investigation
  • iScience
  • Computational and Structural Biotechnology Journal
  • Biochemical and Biophysical Research Communications

The researcher collaborates often with several colleagues, notably:

  • Toshihiro Ito
  • Eigo Kawahara
  • Toshiro Hirai
  • Yasuo Yoshioka
  • Airi Makino

Takehiko Shibata's contributions provide insights especially relevant to understanding immune responses and viral pathogenesis in respiratory infections, integrating molecular biology with clinical and epidemiological perspectives.

Best Publications

  • CELL-FREE PRODUCTION AND STABLE-ISOTOPE LABELING OF MILLIGRAM QUANTITIES OF PROTEINS

    Takanori Kigawa;Takashi Yabuki;Yasuhiko Yoshida;Michio Tsutsui

  • Purified Escherichia coli recA protein catalyzes homologous pairing of superhelical DNA and single-stranded fragments.

    Takehiko Shibata;Chanchal Dasgupta;Richard P. Cunningham;Charles M. Radding

  • Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination

    Munenori Furuse;Yuko Nagase;Hideo Tsubouchi;Kimiko Murakami-Murofushi

  • Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs

    Kouji Hirota;Kouji Hirota;Tomoichiro Miyoshi;Kazuto Kugou;Charles S. Hoffman

  • Homologous pairing in genetic recombination: recA protein makes joint molecules of gapped circular DNA and closed circular DNA

    Richard P. Cunningham;Chanchal DasGupta;Takehiko Shibata;Charles M. Radding

  • Changes in chromatin structure at recombination initiation sites during yeast meiosis.

    K Ohta;T Shibata;A Nicolas

  • Crystal Structure of the Homologous-Pairing Domain from the Human Rad52 Recombinase in the Undecameric Form

    Wataru Kagawa;Hitoshi Kurumizaka;Ryuichiro Ishitani;Shuya Fukai

  • Homologous pairing in genetic recombination: complexes of recA protein and DNA.

    Takehiko Shibata;Richard P. Cunningham;Chanchal Dasgupta;Charles M. Radding

  • Regional polysterism in the GTP-bound form of the human c-Ha-Ras protein.

    Yutaka Ito;Kazuhiko Yamasaki;Junji Iwahara;Tohru Terada

  • Mapping of genes determining nonpermissiveness and host-specific restriction to bacteriophages in Bacillus subtilis Marburg.

    Hiuga Saito;Takehiko Shibata;Tadahiko Ando

  • Single strands induce recA protein to unwind duplex DNA for homologous pairing

    Richard P. Cunningham;Takehiko Shibata;Chanchal DasGupta;Charles M. Radding

  • Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot

    Takatomi Yamada;Ken-ichi Mizuno;Kouji Hirota;Ning Kon

  • The topology of homologous pairing promoted by RecA protein

    Chanchal DasGupta;Takehiko Shibata;Richard P. Cunningham;Charles M. Radding

  • The N-terminal domain of the human Rad51 protein binds DNA: structure and a DNA binding surface as revealed by NMR.

    Hideki Aihara;Yutaka Ito;Hitoshi Kurumizaka;Shigeyuki Yokoyama

  • The trichothecene biosynthesis gene cluster of Fusarium graminearum F15 contains a limited number of essential pathway genes and expressed non-essential genes.

    Makoto Kimura;Takeshi Tokai;Kerry O’Donnell;Todd J Ward

  • Homologous pairing promoted by the human Rad52 protein.

    Wataru Kagawa;Hitoshi Kurumizaka;Shukuko Ikawa;Shigeyuki Yokoyama

  • Homologous pairing in genetic recombination. Purification and characterization of Escherichia coli recA protein.

    T Shibata;R P Cunningham;C M Radding

  • An enzyme with a deep trefoil knot for the active-site architecture.

    Osamu Nureki;Mikako Shirouzu;Kyoko Hashimoto;Ryuichiro Ishitani

  • Contribution of histone N-terminal tails to the structure and stability of nucleosomes

    Wakana Iwasaki;Yuta Miya;Naoki Horikoshi;Akihisa Osakabe

  • Homologous-pairing activity of the human DNA-repair proteins Xrcc3.Rad51C.

    Hitoshi Kurumizaka;Shukuko Ikawa;Maki Nakada;Keiko Eda

Frequent Co-Authors

Hitoshi Kurumizaka
Hitoshi Kurumizaka University of Tokyo
Seiki Kuramitsu
Seiki Kuramitsu Osaka University
Kunihiro Ohta
Kunihiro Ohta University of Tokyo
Mikako Shirouzu
Mikako Shirouzu RIKEN Center for Biosystems Dynamics Research
Charles M. Radding
Charles M. Radding Yale University
Ernest D. Laue
Ernest D. Laue University of Cambridge
Koji Takio
Koji Takio University of Washington

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