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Hitoshi Kurumizaka

Hitoshi Kurumizaka

D-Index & Metrics

Molecular Biology

D-Index
79
Citations
17033
World Ranking
1053
National Ranking
82

Overview

Hitoshi Kurumizaka is affiliated with the University of Tokyo in Japan and works primarily in the field of Biochemistry, Genetics and Molecular Biology, with a strong focus on Molecular Biology.

Their research spans multiple subfields including Molecular Biology, Plant Science, Biomaterials, Genetics, and Structural Biology. The main topics of their work cover:

  • Genomics and Chromatin Dynamics
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • DNA Repair Mechanisms
  • DNA and Nucleic Acid Chemistry
  • RNA Research and Splicing

Recent notable papers authored or co-authored by Kurumizaka include:

  • "Structural basis for the inhibition of cGAS by nucleosomes," 2020, Science
  • "Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT," 2022, Science
  • "Interaction of the pioneer transcription factor GATA3 with nucleosomes," 2020, Nature Communications
  • "Contributions of Histone Variants in Nucleosome Structure and Function," 2020, Journal of Molecular Biology
  • "H4K20me1 and H3K27me3 are concurrently loaded onto the inactive X chromosome but dispensable for inducing gene silencing," 2021, EMBO Reports

Frequent co-authors collaborating with Kurumizaka include:

  • Tomoya Kujirai
  • Yoshimasa Takizawa
  • Lumi Negishi
  • Shoko Sato
  • Haruhiko Ehara

Their research has been published extensively in venues such as:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Communications Biology
  • Journal of Molecular Biology

Best Publications

  • Crystal structure of the human centromeric nucleosome containing CENP-A

    Hiroaki Tachiwana;Wataru Kagawa;Tatsuya Shiga;Akihisa Osakabe

  • Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells.

    Jong Soo Kim;Tatiana B. Krasieva;Hitoshi Kurumizaka;David J. Chen

  • Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1

    Jan Bednar;Isabel Garcia-Saez;Ramachandran Boopathi;Amber R. Cutter

  • Histone acetylation: influence on transcription, nucleosome mobility and positioning, and linker histone-dependent transcriptional repression.

    Kiyoe Ura;Hitoshi Kurumizaka;Stefan Dimitrov;Geneviève Almouzni

  • Crystal Structure of the Homologous-Pairing Domain from the Human Rad52 Recombinase in the Undecameric Form

    Wataru Kagawa;Hitoshi Kurumizaka;Ryuichiro Ishitani;Shuya Fukai

  • Mislocalization of the Centromeric Histone Variant CenH3/CENP-A in Human Cells Depends on the Chaperone DAXX

    Nicolas Lacoste;Adam Woolfe;Hiroaki Tachiwana;Ana Villar Garea

  • Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

    Yoko Hayashi-Takanaka;Kazuo Yamagata;Teruhiko Wakayama;Timothy J. Stasevich

  • Structural Basis of Heterochromatin Formation by Human HP1

    Shinichi Machida;Yoshimasa Takizawa;Masakazu Ishimaru;Yukihiko Sugita

  • Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T

    Hiroaki Tachiwana;Wataru Kagawa;Akihisa Osakabe;Koichiro Kawaguchi

  • Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway

    Kimiyo N. Yamamoto;Shunsuke Kobayashi;Masataka Tsuda;Hitoshi Kurumizaka

  • Structural basis of replication origin recognition by the DnaA protein.

    Norie Fujikawa;Hitoshi Kurumizaka;Osamu Nureki;Takaho Terada

  • The N-terminal domain of the human Rad51 protein binds DNA: structure and a DNA binding surface as revealed by NMR.

    Hideki Aihara;Yutaka Ito;Hitoshi Kurumizaka;Shigeyuki Yokoyama

  • Homologous pairing promoted by the human Rad52 protein.

    Wataru Kagawa;Hitoshi Kurumizaka;Shukuko Ikawa;Shigeyuki Yokoyama

  • Expression and purification of recombinant human histones.

    Yoshinori Tanaka;Maki Tawaramoto-Sasanuma;Shinichi Kawaguchi;Tsutomu Ohta

  • Structural basis for the inhibition of cGAS by nucleosomes

    Tomoya Kujirai;Christian Zierhut;Yoshimasa Takizawa;Ryan Kim

  • Structural basis of the nucleosome transition during RNA polymerase II passage.

    Tomoya Kujirai;Haruhiko Ehara;Yuka Fujino;Yuka Fujino;Mikako Shirouzu

  • RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination.

    Shojiro Inano;Koichi Sato;Yoko Katsuki;Wataru Kobayashi

  • A FancD2-Monoubiquitin Fusion Reveals Hidden Functions of Fanconi Anemia Core Complex in DNA Repair

    Nobuko Matsushita;Hiroyuki Kitao;Masamichi Ishiai;Naoki Nagashima

  • Solution structure of the DNA binding domain of a nucleoid-associated protein, H-NS, from Escherichia coli

    Heisaburo Shindo;Takanobu Iwaki;Ryoichi Ieda;Hitoshi Kurumizaka

  • Contribution of histone N-terminal tails to the structure and stability of nucleosomes

    Wakana Iwasaki;Yuta Miya;Naoki Horikoshi;Akihisa Osakabe

Frequent Co-Authors

Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Yasuyuki Ohkawa
Yasuyuki Ohkawa Kyushu University
Takehiko Shibata
Takehiko Shibata Yokohama City University
Minoru Takata
Minoru Takata Kyoto University
Yoshifumi Nishimura
Yoshifumi Nishimura Hiroshima University
Tatsuo Fukagawa
Tatsuo Fukagawa Osaka University
Jun-ichi Nakayama
Jun-ichi Nakayama National Institute for Basic Biology
Paul A. Wade
Paul A. Wade National Institutes of Health
Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology

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