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Biology and Biochemistry

D-Index
42
Citations
10079
World Ranking
19453
National Ranking
1404

Overview

Jun-ichi Nakayama is affiliated with the National Institute for Basic Biology in Japan and contributes primarily to the field of Biochemistry, Genetics and Molecular Biology. Their research has a strong focus on molecular biology, as evidenced by the majority of their publications in this subfield.

Their scientific work covers several key topics, including:

  • Genomics and Chromatin Dynamics
  • RNA Research and Splicing
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Fungal and yeast genetics research
  • Cancer-related gene regulation

Nakayama has published extensively in venues such as bioRxiv (Cold Spring Harbor Laboratory), The FASEB Journal, Genes to Cells, The Journal of Biochemistry, and Nucleic Acids Research. These journals reflect a focus on both foundational molecular biology and applied biochemical research.

Notable recent papers authored under their influence or collaboration include:

  • Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19, 2020, eLife
  • Researchers support preprints and open access publishing, but with reservations: A questionnaire survey of MBSJ members, 2023, Genes to Cells
  • Identification and characterization of the de novo methyltransferases for eukaryotic N6-methyladenine (6mA), 2025, Science Advances
  • Regulation of the SUV39H Family Methyltransferases: Insights from Fission Yeast, 2023, Biomolecules
  • Cooperative DNA-binding activities of Chp2 are critical for its function in heterochromatin assembly, 2023, The Journal of Biochemistry

Frequent collaborators in Nakayama's research include Yuriko Yoshimura, Reiko Nakagawa, Aki Hayashi, Rinko Nakamura, and Jun Ueda. This network of coauthors points to a collaborative approach within Japanese molecular biology research circles.

Best Publications

  • Role of Histone H3 Lysine 9 Methylation in Epigenetic Control of Heterochromatin Assembly

    Jun-ichi Nakayama;Judd C. Rice;Brian D. Strahl;C. David Allis

  • Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas.

    J.-I. Nakayama;H. Tahara;E. Tahara;M. Saito

  • Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b.

    Akiko Tsumura;Tomohiro Hayakawa;Yuichi Kumaki;Shin-ichiro Takebayashi

  • TLP1: A Gene Encoding a Protein Component of Mammalian Telomerase Is a Novel Member of WD Repeats Family

    Jun-ichi Nakayama;Motoki Saito;Hideo Nakamura;Akira Matsuura

  • Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa.

    Hisashi Tamaru;Xing Zhang;Debra McMillen;Prim B. Singh

  • Structural Basis of Heterochromatin Formation by Human HP1

    Shinichi Machida;Yoshimasa Takizawa;Masakazu Ishimaru;Yukihiko Sugita

  • A chromodomain protein, Chp1, is required for the establishment of heterochromatin in fission yeast

    Mahito Sadaie;Tetsushi Iida;Takeshi Urano;Jun-ichi Nakayama

  • Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections.

    Hidetoshi Tahara;Wataru Yasui;Eiji Tahara;Junya Fujimoto

  • A chromodomain protein, Swi6, performs imprinting functions in fission yeast during mitosis and meiosis.

    Jun-ichi Nakayama;Amar J.S Klar;Shiv I.S Grewal

  • Physiological Roles of Class I HDAC Complex and Histone Demethylase

    Tomohiro Hayakawa;Jun-ichi Nakayama

  • A novel quantitative 'stretch PCR assay', that detects a dramatic increase in telomerase activity during the progression of myeloid leukemias.

    K.-I. Tatematsu;J.-I. Nakayama;M. Danbara;S. Shionoya

  • The heterochromatin protein Swi6/HP1 activates replication origins at the pericentromeric region and silent mating-type locus.

    Makoto T. Hayashi;Tatsuro S. Takahashi;Takuro Nakagawa;Jun Ichi Nakayama

  • Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast

    Shane M Buker;Tetsushi Iida;Marc Bühler;Judit Villén

  • Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice.

    Xunmei Yuan;Shun Ishibashi;Shinji Hatakeyama;Motoki Saito

  • The UUAG-specific RNA Binding Protein, Heterogeneous Nuclear Ribonucleoprotein D0: COMMON MODULAR STRUCTURE AND BINDING PROPERTIES OF THE 2xRBD-Gly FAMILY (∗)

    Yasuko Kajita;Jun-ichi Nakayama;Masuo Aizawa;Fuyuki Ishikawa

  • Balance between Distinct HP1 Family Proteins Controls Heterochromatin Assembly in Fission Yeast

    Mahito Sadaie;Rika Kawaguchi;Yasuko Ohtani;Fumio Arisaka

  • A role for DNA polymerase α in epigenetic control of transcriptional silencing in fission yeast

    Jun-ichi Nakayama;Robin C. Allshire;Amar J.S. Klar;Shiv I.S. Grewal

  • Telomerase Activity and Telomerase Subunits Gene Expression Patterns in Neuroblastoma: A Molecular and Immunohistochemical Study Establishing Prognostic Tools for Fresh-Frozen and Paraffin-Embedded Tissues

    Christopher Poremba;Christina Scheel;Barbara Hero;Holger Christiansen

  • Fission yeast CENP-B homologs nucleate centromeric heterochromatin by promoting heterochromatin-specific histone tail modifications.

    Hiromi Nakagawa;Joon-Kyu Lee;Jerard Hurwitz;Robin C. Allshire

  • RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation

    Tomohiro Hayakawa;Yasuko Ohtani;Noriyo Hayakawa;Kaori Shinmyozu

Frequent Co-Authors

Fuyuki Ishikawa
Fuyuki Ishikawa Kyoto University
Hitoshi Kurumizaka
Hitoshi Kurumizaka University of Tokyo
Shiv I. S. Grewal
Shiv I. S. Grewal National Institutes of Health
Takeshi Urano
Takeshi Urano Shimane University
Eiichi Tahara
Eiichi Tahara Hiroshima University
Wataru Yasui
Wataru Yasui Hiroshima University
Hidetoshi Tahara
Hidetoshi Tahara Hiroshima University
Yoshifumi Nishimura
Yoshifumi Nishimura Hiroshima University
Karl Ekwall
Karl Ekwall Karolinska Institute
Yasushi Hiraoka
Yasushi Hiraoka Osaka University

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