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Genetics

D-Index
57
Citations
12965
World Ranking
3400
National Ranking
42

Overview

Karl Ekwall is affiliated with the Karolinska Institute in Sweden. Their research contributions primarily focus on biochemistry, genetics, and molecular biology, with a specialized emphasis on molecular biology. Their work spans related subfields including plant science, cancer research, hematology, and physiology.

The central themes of Karl Ekwall's scientific investigations encompass genomics and chromatin dynamics, fungal and yeast genetics research, plant molecular biology research, epigenetics and DNA methylation, plant reproductive biology, insect resistance and genetics, and CRISPR and genetic engineering.

Recent notable publications by Karl Ekwall include:

  • Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes (2021) published in Nature Communications
  • Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforces genome-wide H3K4me1 profiles and influences cell growth and gene expression (2020) published in Clinical Epigenetics
  • High-Throughput Flow Cytometry Combined with Genetic Analysis Brings New Insights into the Understanding of Chromatin Regulation of Cellular Quiescence (2020) published in International Journal of Molecular Sciences
  • AML displays increased CTCF occupancy associated with aberrant gene expression and transcription factor binding (2020) published in Blood
  • Abo1 is required for the H3K9me2 to H3K9me3 transition in heterochromatin (2020) published in Scientific Reports

Frequent coauthors working with Karl Ekwall include:

  • Andreas Lennartsson
  • Lina Cordeddu
  • Yasaman Zahedi
  • Adrien Birot
  • Sabine Vaur

Karl Ekwall's research has been published across various scientific journals. Frequent publication venues include:

  • International Journal of Molecular Sciences
  • Nature Communications
  • Clinical Epigenetics
  • Blood
  • Scientific Reports

Best Publications

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation.

    R Allshire;E Nimmo;K Ekwall;Jean-Paul Javerzat

  • Comparative functional genomics of the fission yeasts

    Nicholas Rhind;Zehua Chen;Moran Yassour;Moran Yassour;Dawn A. Thompson

  • Transient Inhibition of Histone Deacetylation Alters the Structural and Functional Imprint at Fission Yeast Centromeres

    Karl Ekwall;Tim Olsson;Bryan M. Turner;Gwen Cranston

  • Sin3: a flexible regulator of global gene expression and genome stability.

    Rebecca A. Silverstein;Karl Ekwall

  • The chromodomain protein Swi6 : a key component at fission yeast centromeres

    Karl Ekwall;Jean-Paul Javerzat;Axel Lorentz;Henning Schmidt

  • FANTOM5 CAGE profiles of human and mouse samples

    Shuhei Noguchi;Takahiro Arakawa;Shiro Fukuda;Masaaki Furuno

  • Mutations in the fission yeast silencing factors clr4 + and rik1 + disrupt the localisation of the chromo domain protein Swi6p and impair centromere function

    Karl Ekwall;Elaine R. Nimmo;Jean-Paul Javerzat;Britta Borgstrøm

  • Histone modification patterns and epigenetic codes.

    Andreas Lennartsson;Karl Ekwall

  • Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae

    Alexandra B Lantermann;Tobias Straub;Annelie Strålfors;Guo-Cheng Yuan

  • Functional Divergence between Histone Deacetylases in Fission Yeast by Distinct Cellular Localization and In Vivo Specificity

    Pernilla Bjerling;Rebecca A. Silverstein;Geneviève Thon;Amy Caudy

  • RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing

    Ingela Djupedal;Manuela Portoso;Henrik Spåhr;Carolina Bonilla

  • Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe.

    Robin C. Allshire;Karl Ekwall

  • Dicer is required for chromosome segregation and gene silencing in fission yeast cells

    Patrick Provost;Rebecca A. Silverstein;David Dishart;Julian Walfridsson

  • Genome wide analysis of nucleosome density histone acetylation and HDAC function in fission yeast

    Marianna Wirén;Rebecca A Silverstein;Indranil Sinha;Julian Walfridsson

  • Genome-wide analysis of HDAC function

    Karl Ekwall

  • Mutations in rik1, clr2, clr3 and clr4 genes asymmetrically derepress the silent mating-type loci in fission yeast.

    K Ekwall;T Ruusala

  • Epigenetics: heterochromatin meets RNAi.

    Ingela Djupedal;Karl Ekwall

  • Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions

    Xuefeng Zhu;Marianna Wirén;Indranil Sinha;Nina N. Rasmussen

  • Identification of Noncoding Transcripts from within CENP-A Chromatin at Fission Yeast Centromeres

    Eun Shik Choi;Annelie Strålfors;Araceli G. Castillo;Mickaël Durand-Dubief

Frequent Co-Authors

Robin C. Allshire
Robin C. Allshire University of Edinburgh
Juha Kere
Juha Kere Karolinska Institute
Frank Brombacher
Frank Brombacher University of Cape Town
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Timo Lassmann
Timo Lassmann Telethon Kids Institute
Alistair R. R. Forrest
Alistair R. R. Forrest Harry Perkins Institute of Medical Research
Stefano Gustincich
Stefano Gustincich Italian Institute of Technology

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