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Neuroscience

D-Index
46
Citations
6196
World Ranking
6780
National Ranking
2930

Overview

Othman Ghribi is affiliated with the University of North Dakota in the United States. Their research spans multiple interconnected fields, particularly focusing on neurobiology and molecular mechanisms related to neurodegenerative diseases and toxicity in organisms.

The scientist has contributed to research on topics including:

  • Parkinson's Disease Mechanisms and Treatments
  • Aluminum toxicity and tolerance in plants and animals
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Protein Structure and Dynamics
  • Molecular spectroscopy and chirality
  • Diet and metabolism studies

Othman Ghribi's work has appeared in several notable publication venues, with multiple contributions to:

  • Neuroscience
  • Journal of Alzheimer s Disease
  • Neurobiology of Disease
  • Journal of Chemical Information and Modeling
  • Journal of Neuroinflammation

Their recent papers include:

  • Folding Free-Energy Landscape of α-Synuclein (35-97) Via Replica Exchange Molecular Dynamics, 2020, Journal of Chemical Information and Modeling
  • Alpha-Synuclein-induced DNA Methylation and Gene Expression in Microglia, 2021, Neuroscience
  • Corrigendum to "Alpha-Synuclein-induced DNA Methylation and Gene Expression in Microglia" [Neuroscience 468 (2021) 186-198], 2022, Neuroscience
  • Correction: Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease, 2023, Journal of Neuroinflammation
  • Retraction to: Cyclosporin A inhibits Al-induced cytochrome c release from mitochondria in aged rabbits, 2024, Journal of Alzheimer s Disease

Ghribi frequently collaborates with other researchers, with several co-authors appearing in multiple publications. Frequent co-authors include:

  • Mary M. Herman
  • John Savory
  • Jared Schommer
  • Brett A. McGregor
  • Md. Obayed Raihan

In their research, Othman Ghribi explores a wide range of subfields, primarily:

  • Physiology
  • Neurology
  • Cellular and Molecular Neuroscience
  • Plant Science
  • Molecular Biology

Best Publications

  • Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: a meta-analysis.

    M. Schrag;C. Mueller;M. Zabel;A. Crofton

  • Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on β-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells

    Jaya Rp Prasanthi;Amber Huls;Sarah Thomasson;Alex Thompson

  • Ovarian steroids and selective estrogen receptor modulators activity on rat brain NMDA and AMPA receptors.

    Michel Cyr;Othman Ghribi;Caroline Thibault;Marc Morissette

  • High cholesterol content in neurons increases BACE, β-amyloid, and phosphorylated tau levels in rabbit hippocampus

    Othman Ghribi;Brian Larsen;Matthew Schrag;Mary M. Herman

  • Caffeine protects against oxidative stress and Alzheimer's disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet

    Jaya R.P. Prasanthi;Bhanu Dasari;Gurdeep Marwarha;Tyler Larson

  • Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease

    Xuesong Chen;Jeremy W Gawryluk;John F Wagener;Othman Ghribi

  • Caffeine protects against disruptions of the blood-brain barrier in animal models of Alzheimer's and Parkinson's diseases.

    Xuesong Chen;Othman Ghribi;Jonathan D. Geiger

  • Leptin Reduces the Accumulation of Aβ and Phosphorylated Tau Induced by 27-Hydroxycholesterol in Rabbit Organotypic Slices

    Gurdeep Marwarha;Bhanu Dasari;Jaya R.P. Prasanthi;Jared Schommer

  • Intracellular mechanisms underlying aluminum-induced apoptosis in rabbit brain.

    John Savory;Mary M Herman;Othman Ghribi

  • Deposition of iron and β‐amyloid plaques is associated with cortical cellular damage in rabbits fed with long‐term cholesterol‐enriched diets

    Othman Ghribi;Mikhail Y. Golovko;Brian Larsen;Matthew Schrag

  • Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway.

    Gurdeep Marwarha;Shaneabbas Raza;Craig Meiers;Othman Ghribi

  • Co-involvement of Mitochondria and Endoplasmic Reticulum in Regulation of Apoptosis: Changes in Cytochrome c, Bcl-2 and Bax in the Hippocampus of Aluminum-treated Rabbits

    Othman Ghribi;David A DeWitt;Michael S Forbes;Mary M Herman

  • GDNF protects against aluminum-induced apoptosis in rabbits by upregulating Bcl-2 and Bcl-XL and inhibiting mitochondrial Bax translocation.

    Othman Ghribi;Mary M. Herman;Michael S. Forbes;David A. DeWitt

  • Lithium inhibits aluminum-induced apoptosis in rabbit hippocampus, by preventing cytochrome c translocation, Bcl-2 decrease, Bax elevation and caspase-3 activation.

    Othman Ghribi;Mary M. Herman;Natalie K. Spaulding;John Savory

  • Mechanisms of aluminum-induced neurodegeneration in animals: Implications for Alzheimer's disease.

    John Savory;Mary M. Herman;Othman Ghribi

  • Alteration of glutamate receptors in the striatum of dyskinetic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys following dopamine agonist treatment.

    Frédéric Calon;Marc Morissette;Othman Ghribi;Martin Goulet

  • Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and α-synuclein in human neuroblastoma SH-SY5Y cells

    Jaya Prasanthi Rantham Prabhakara;Gwen Feist;Sarah Thomasson;Alex Thompson

  • The oxysterol 27-hydroxycholesterol regulates α-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors--relevance to Parkinson's disease.

    Gurdeep Marwarha;Turk Rhen;Trevor Schommer;Othman Ghribi

  • Cholinergic systems and long-term potentiation in memory-impaired apolipoprotein E-deficient mice.

    P. Krzywkowski;O. Ghribi;J. Gagné;C. Chabot

  • Silencing GADD153/CHOP Gene Expression Protects against Alzheimer's Disease-Like Pathology Induced by 27-Hydroxycholesterol in Rabbit Hippocampus

    Jaya R. P. Prasanthi;Tyler Larson;Jared Schommer;Othman Ghribi

Frequent Co-Authors

Mary M. Herman
Mary M. Herman National Institutes of Health
Marc Morissette
Marc Morissette Université Laval
Frédéric Calon
Frédéric Calon Université Laval
Rosanna Squitti
Rosanna Squitti Centro San Giovanni di Dio Fatebenefratelli
Richard Grondin
Richard Grondin University of Kentucky
Paul J. Bédard
Paul J. Bédard Université Laval

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