Anthony W. Segal

Overview

Best Publications

• HOW NEUTROPHILS KILL MICROBES

  Anthony W. Segal

  2263
  Citations

• Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.

  Erik-Oliver Glocker;Daniel Kotlarz;Kaan Boztug;E. Michael Gertz

  1678
  Citations

• Killing activity of neutrophils is mediated through activation of proteases by K + flux

  Emer P. Reeves;Hui Lu;Hugues Lortat Jacobs;Carlo G. M. Messina

  1414
  Citations

• Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1.

  Arie Abo;Edgar Pick;Alan Hall;Nicholas Totty

  1171
  Citations

• The biochemical basis of the NADPH oxidase of phagocytes

  Anthony W. Segal;Arie Abo

  792
  Citations

• The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems.

  Andrew R Cross;Anthony W Segal

  593
  Citations

• Elemental diet as primary treatment of acute Crohn's disease: a controlled trial.

  C O'Moráin;A W Segal;A J Levi

  576
  Citations

• Indium-111-labeled autologous leukocytes in man.

  Thakur Ml;Lavender Jp;Arnot Rn;Silvester Dj

  525
  Citations

• Interaction of Rac with p67phox and regulation of phagocytic NADPH oxidase activity

  Dagmar Diekmann;Arie Abo;Caroline Johnston;Anthony W. Segal

  523
  Citations

• Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

  Andrew M. Smith;Farooq Z. Rahman;Bu'Hussain Hayee;Simon J. Graham

  508
  Citations

• Defective acute inflammation in Crohn's disease : a clinical investigation

  Daniel J B Marks;Marcus W N Harbord;Raymond MacAllister;Farooq Z Rahman

  501
  Citations

• The respiratory burst of phagocytic cells is associated with a rise in vacuolar pH

  Anthony W. Segal;Michael Geisow;Rodolfo Garcia;Angela Harper

  494
  Citations

• Mutations in the X-linked and autosomal recessive forms of chronic granulomatous disease

  D Roos;M de Boer;F Kuribayashi;C Meischl

  491
  Citations

• Impaired Immunity and Enhanced Resistance to Endotoxin in the Absence of Neutrophil Elastase and Cathepsin G

  Josephine Tkalcevic;Marco Novelli;Marios Phylactides;John P Iredale

  451
  Citations

• Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription.

  K H In;K Asano;D Beier;J Grobholz

  434
  Citations

• Novel cytochrome b system in phagocytic vacuoles of human granulocytes.

  Anthony W. Segal;Owen T. G. Jones

  432
  Citations

• Cytochrome b-245 is a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes

  A W Segal;I West;F Wientjes;J H A Nugent

  428
  Citations

• p40phox, a third cytosolic component of the activation complex of the NADPH oxidase to contain src homology 3 domains.

  F B Wientjes;J J Hsuan;N F Totty;A W Segal

  392
  Citations

• Absence of both cytochrome b −245 subunits from neutrophils in X-linked chronic granulomatous disease

  Anthony W. Segal

  384
  Citations

• The X-linked chronic granulomatous disease gene codes for the β -chain of cytochrome b −245

  Carmel Teahan;Peter Rowe;Peter Parker;Nick Totty

  380
  Citations