D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 89 Citations 29,775 331 World Ranking 1628 National Ranking 113

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Anthony W. Segal spends much of his time researching Biochemistry, Oxidase test, NADPH oxidase, Chronic granulomatous disease and Cytochrome. He has researched Biochemistry in several fields, including Azurophilic granule and Myeloperoxidase. The study incorporates disciplines such as Respiratory burst, Phagocytosis and Membrane protein in addition to Oxidase test.

His NADPH oxidase research incorporates elements of Protein kinase C, GTP' and G protein. The study incorporates disciplines such as Internal medicine, Pathogenesis and X chromosome in addition to Chronic granulomatous disease. The various areas that Anthony W. Segal examines in his Cytochrome study include Molecular biology, Cytochrome c and Flavin group.

His most cited work include:

  • HOW NEUTROPHILS KILL MICROBES (1296 citations)
  • Inflammatory bowel disease and mutations affecting the interleukin-10 receptor. (1005 citations)
  • Killing activity of neutrophils is mediated through activation of proteases by K + flux (947 citations)

What are the main themes of his work throughout his whole career to date?

Anthony W. Segal mostly deals with Biochemistry, Immunology, NADPH oxidase, Oxidase test and Chronic granulomatous disease. Anthony W. Segal has researched Biochemistry in several fields, including Biophysics, Phagocytosis and Myeloperoxidase. Anthony W. Segal has included themes like Crohn's disease, Disease, Inflammatory bowel disease and Macrophage in his Immunology study.

His NADPH oxidase research incorporates themes from Respiratory burst, Molecular biology, Superoxide and Cytosol. His Oxidase test study frequently draws connections between adjacent fields such as Cytochrome. His study on Chronic granulomatous disease also encompasses disciplines like

  • Pathology that connect with fields like Gastroenterology,
  • Microbiology, which have a strong connection to Bacteria.

He most often published in these fields:

  • Biochemistry (28.31%)
  • Immunology (27.41%)
  • NADPH oxidase (25.30%)

What were the highlights of his more recent work (between 2013-2019)?

  • Immunology (27.41%)
  • Inflammation (11.75%)
  • NADPH oxidase (25.30%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Immunology, Inflammation, NADPH oxidase, Inflammatory bowel disease and Genetics. His Immunology research incorporates elements of Crohn's disease and Ashkenazi jews. His biological study spans a wide range of topics, including Intestinal mucosa, Cytokine, Secretion, Ulcerative colitis and Macrophage.

His NADPH oxidase study introduces a deeper knowledge of Biochemistry. His studies deal with areas such as Biophysics and Myeloperoxidase as well as Biochemistry. His study in Oxidase test is interdisciplinary in nature, drawing from both Superoxide and Chronic granulomatous disease.

Between 2013 and 2019, his most popular works were:

  • Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease. (132 citations)
  • Alkalinity of neutrophil phagocytic vacuoles is modulated by HVCN1 and has consequences for myeloperoxidase activity. (55 citations)
  • The Human Salivary Microbiome Is Shaped by Shared Environment Rather than Genetics: Evidence from a Large Family of Closely Related Individuals. (49 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Anthony W. Segal mainly focuses on Immunology, Genetics, Genome-wide association study, Inflammation and Exome sequencing. His studies in Immunology integrate themes in fields like Intestinal mucosa, LRRK2, Ashkenazi jews, Macrophage and Haplotype. His study on Pedigree chart, Human microbiome and Genetic marker is often connected to Extended family as part of broader study in Genetics.

His Inflammation research is multidisciplinary, incorporating elements of Optineurin, Colitis, Pathogenesis and Secretion, Cytokine secretion. His research in Monocyte tackles topics such as Phagocytosis which are related to areas like NADPH oxidase. His work in NADPH oxidase tackles topics such as Antimicrobial which are related to areas like Biochemistry.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

HOW NEUTROPHILS KILL MICROBES

Anthony W. Segal.
Annual Review of Immunology (2005)

1945 Citations

Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.

Erik-Oliver Glocker;Daniel Kotlarz;Kaan Boztug;E. Michael Gertz.
The New England Journal of Medicine (2009)

1471 Citations

Killing activity of neutrophils is mediated through activation of proteases by K + flux

Emer P. Reeves;Hui Lu;Hugues Lortat Jacobs;Carlo G. M. Messina.
Nature (2002)

1327 Citations

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1.

Arie Abo;Edgar Pick;Alan Hall;Nicholas Totty.
Nature (1991)

1149 Citations

CHRONIC GRANULOMATOUS-DISEASE

Adrian J. Thrasher;Nicholas H. Keep;Frans Wientjes;Anthony W. Segal.
Biochimica et Biophysica Acta (1994)

811 Citations

The biochemical basis of the NADPH oxidase of phagocytes

Anthony W. Segal;Arie Abo.
Trends in Biochemical Sciences (1993)

741 Citations

The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems.

Andrew R Cross;Anthony W Segal.
Biochimica et Biophysica Acta (2004)

554 Citations

Elemental diet as primary treatment of acute Crohn's disease: a controlled trial.

C O'Moráin;A W Segal;A J Levi.
BMJ (1984)

550 Citations

Indium-111-labeled autologous leukocytes in man.

Thakur Ml;Lavender Jp;Arnot Rn;Silvester Dj.
The Journal of Nuclear Medicine (1977)

518 Citations

The respiratory burst of phagocytic cells is associated with a rise in vacuolar pH

Anthony W. Segal;Michael Geisow;Rodolfo Garcia;Angela Harper.
Nature (1981)

480 Citations

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