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D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
17256
World Ranking
5133
National Ranking
389

Overview

Geoffrey J. Laurent was affiliated with University College London in the United Kingdom. Their research mainly focused on the field of Medicine, with specific attention to Pulmonary and Respiratory Medicine, Oncology, Public Health, Environmental and Occupational Health, Molecular Biology, and Genetics.

The scientist contributed publications primarily related to lung diseases and cancer, covering topics such as interstitial lung diseases and idiopathic pulmonary fibrosis, occupational exposure and asthma, occupational and environmental lung diseases, cytokine signaling pathways and interactions, lung cancer treatments and mutations, fibroblast growth factor research, and cancer cells and metastasis.

Notable recent papers included:

  • Plasma cell but not CD20-mediated B-cell depletion protects from bleomycin-induced lung fibrosis, 2022, European Respiratory Journal
  • Reduced SOCS1 Expression in Lung Fibroblasts from Patients with IPF Is Not Mediated by Promoter Methylation or Mir155, 2021, Biomedicines

Frequent co-authors who appeared in multiple publications with Geoffrey J. Laurent were:

  • Cecilia M. Prêle
  • Tylah Miles
  • David R. Pearce
  • Matthias Ernst
  • Darryl A. Knight

The main publication venues for their work included the European Respiratory Journal and Biomedicines. Their contributions in these journals often intersected with respiratory medicine and molecular research related to lung conditions.

Best Publications

  • Mechanisms of tissue repair: from wound healing to fibrosis

    Steven E. Mutsaers;Jill E. Bishop;Gus McGrouther;Geoffrey J. Laurent

  • Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome.

    Richard P Marshall;Suzanne Webb;Geoffrey J Bellingan;Hugh E Montgomery

  • Common Promoter Variant in Cyclooxygenase-2 Represses Gene Expression. Evidence of Role in Acute-Phase Inflammatory Response

    Anastasia Papafili;Michael R. Hill;David J. Brull;Robin J. McAnulty

  • Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.

    R. Gisli Jenkins;Xiao Su;George Su;Christopher J. Scotton

  • Idiopathic pulmonary fibrosis: multiple causes and multiple mechanisms?

    T M Maher;A U Wells;G J Laurent

  • Mast cell tryptase stimulates human lung fibroblast proliferation via protease-activated receptor-2

    Ian A. Akers;Maddy Parsons;Michael R. Hill;Morley D. Hollenberg

  • Pulmonary fibrosis: searching for model answers.

    Felix Chua;Jack Gauldie;Geoffrey J. Laurent

  • An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis.

    R. Gisli Jenkins;Bethany B. Moore;Rachel C. Chambers;Oliver Eickelberg

  • Pulmonary fibrosis: cytokines in the balance

    RK Coker;GJ Laurent

  • Angiotensin II and the fibroproliferative response to acute lung injury

    Richard P. Marshall;Peter Gohlke;Rachel C. Chambers;David C. Howell

  • Fibroproliferation occurs early in the acute respiratory distress syndrome and impacts on outcome.

    Richard P. Marshall;Geoffrey Bellingan;Suzanne Webb;Anna Puddicombe

  • Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury

    Chris J. Scotton;Malvina A. Krupiczojc;Melanie Königshoff;Paul F. Mercer

  • Global Expression Profiling of Fibroblast Responses to Transforming Growth Factor-β1 Reveals the Induction of Inhibitor of Differentiation-1 and Provides Evidence of Smooth Muscle Cell Phenotypic Switching

    Rachel C. Chambers;Patricia Leoni;Naftali Kaminski;Geoffrey J. Laurent

  • Cyclooxygenase-2 Deficiency Results in a Loss of the Anti-Proliferative Response to Transforming Growth Factor-β in Human Fibrotic Lung Fibroblasts and Promotes Bleomycin-Induced Pulmonary Fibrosis in Mice

    Carmel B. Keerthisingam;R. Gisli Jenkins;Nicholas K. Harrison;Norma A. Hernandez-Rodriguez

  • Angiotensin II Is Mitogenic for Human Lung Fibroblasts via Activation of the Type 1 Receptor

    Richard P. Marshall;Robin J. McANULTY;Geoffrey J. Laurent

  • Thrombin Is a Potent Inducer of Connective Tissue Growth Factor Production via Proteolytic Activation of Protease-activated Receptor-1

    Rachel C. Chambers;Patricia Leoni;Olivier P. Blanc-Brude;David E. Wembridge

  • Adult familial cryptogenic fibrosing alveolitis in the United Kingdom

    Richard P Marshall;Anna Puddicombe;William O C Cookson;Geoffrey J Laurent

  • Absence of Proteinase-Activated Receptor-1 Signaling Affords Protection from Bleomycin-Induced Lung Inflammation and Fibrosis

    David C.J. Howell;Robin H. Johns;Joseph A. Lasky;Bin Shan

  • Direct Thrombin Inhibition Reduces Lung Collagen, Accumulation, and Connective Tissue Growth Factor mRNA Levels in Bleomycin-Induced Pulmonary Fibrosis

    David C.J. Howell;Neil R. Goldsack;Richard P. Marshall;Robin J. McAnulty

  • Neutrophil elastase: mediator of extracellular matrix destruction and accumulation.

    Felix Chua;Geoffrey J Laurent

Frequent Co-Authors

Rachel C. Chambers
Rachel C. Chambers University College London
Darryl A. Knight
Darryl A. Knight University of Newcastle Australia
Anthony W. Segal
Anthony W. Segal University College London
Philip J. Thompson
Philip J. Thompson University of Western Australia
Toby M. Maher
Toby M. Maher University of Southern California
Meena Kumari
Meena Kumari University of Essex
Oliver Eickelberg
Oliver Eickelberg University of Pittsburgh
Steve E. Humphries
Steve E. Humphries University College London
Hugh Montgomery
Hugh Montgomery University College London
John T. Reeves
John T. Reeves University of Colorado Anschutz Medical Campus

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