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Immunology
Canada
2026

D-Index & Metrics

Immunology

D-Index
110
Citations
45191
World Ranking
503
National Ranking
6

Medicine

D-Index
112
Citations
46024
World Ranking
5143
National Ranking
203

Research.com Recognitions

  • 2026 - Research.com Immunology in Canada Leader Award
  • 2025 - Research.com Immunology in Canada Leader Award
  • 2023 - Research.com Immunology in Canada Leader Award
  • 2022 - Research.com Immunology in Canada Leader Award
  • 1997 - Fellow of the Royal Society of Canada Academy of Science

Overview

Jack Gauldie is affiliated with McMaster University in Canada and has an established publication record primarily in the field of Medicine, with a significant focus on Pulmonary and Respiratory Medicine. Their research includes contributions to subfields such as Immunology, Molecular Biology, Cancer Research, and Physiology.

The scientist's work covers several main topics, including:

  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Pleural and Pulmonary Diseases
  • Neonatal Respiratory Health Research
  • Pulmonary Hypertension Research and Treatments
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • S100 Proteins and Annexins
  • Immune Response and Inflammation

Frequent publication venues for their research include:

  • The Journal of Immunology
  • European Respiratory Journal
  • JCI Insight
  • Respiratory Research
  • American Journal of Physiology-Lung Cellular and Molecular Physiology

Several notable recent papers authored or co-authored by Jack Gauldie feature the following titles, year of publication, and venues:

  • The importance of interventional timing in the bleomycin model of pulmonary fibrosis, 2020, European Respiratory Journal
  • FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis, 2020, JCI Insight
  • Role of matrix metalloprotease-2 and MMP-9 in experimental lung fibrosis in mice, 2022, Respiratory Research
  • Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice, 2020, The Journal of Immunology
  • Role of the COX2-PGE2 axis in S. pneumoniae-induced exacerbation of experimental fibrosis, 2020, American Journal of Physiology-Lung Cellular and Molecular Physiology

Jack Gauldie has collaborated regularly with several researchers including Martin Kolb, Tina Bormann, Tobias Welte, Ulrich A. Maus, and Regina Maus.

In recognition of contributions to the scientific community, Gauldie was awarded the distinction of Fellow of the Royal Society of Canada in 1997 by the Academy of Science.

Best Publications

  • The acute phase response

    Heinz Baumann;Jack Gauldie

  • IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses.

    Z Xing;J Gauldie;G Cox;H Baumann

  • Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells

    Jack Gauldie;Carl Richards;Del Harnish;Peter Lansdorp

  • Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.

    P J Sime;Z Xing;F L Graham;K G Csaky

  • The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

    Antje Moeller;Kjetil Ask;David Warburton;Jack Gauldie

  • Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis.

    Martin Kolb;Peter J. Margetts;Daniel C. Anthony;Fernando Pitossi

  • Circulating Fibrocytes Are an Indicator of Poor Prognosis in Idiopathic Pulmonary Fibrosis

    Antje Moeller;Sarah E. Gilpin;Kjetil Ask;Gerard Cox

  • Regulation of Transforming Growth Factor-beta 1-driven Lung Fibrosis by Galectin-3

    Alison C. Mackinnon;Michael A. Gibbons;Sarah L. Farnworth;Hakon Leffler

  • Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is a Death Receptor for Granzyme B during Cytotoxic T Cell–Induced Apoptosis

    Bruce Motyka;Gregory Korbutt;Michael J Pinkoski;Jeffrey A Heibein

  • Late cutaneous allergic responses in isolated IgE-dependent reactions

    J. Dolovich;J. Dolovich;F.E. Hargreave;F.E. Hargreave;R. Chalmers;R. Chalmers;K.J. Shier;K.J. Shier

  • Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis.

    Michael A Gibbons;Alison C MacKinnon;Prakash Ramachandran;Kevin Dhaliwal

  • Regulation of hepatic acute phase plasma protein genes by hepatocyte stimulating factors and other mediators of inflammation.

    H Baumann;J Gauldie

  • Smad3 Null Mice Develop Airspace Enlargement and Are Resistant to TGF-β-Mediated Pulmonary Fibrosis

    Philippe Bonniaud;Martin Kolb;Martin Kolb;Tom Galt;Jennifer Robertson

  • Interaction among hepatocyte-stimulating factors, interleukin 1, and glucocorticoids for regulation of acute phase plasma proteins in human hepatoma (HepG2) cells.

    H Baumann;C Richards;J Gauldie

  • Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment

    Dalit Barkan;Lara H. El Touny;Aleksandra M. Michalowski;Jane Ann Smith

  • Pulmonary fibrosis: searching for model answers.

    Felix Chua;Jack Gauldie;Geoffrey J. Laurent

  • The effect of thrombocytopenia on experimental arteriosclerotic lesion formation in rabbits. Smooth muscle cell proliferation and re-endothelialization.

    R J Friedman;M B Stemerman;B Wenz;S Moore

  • Mucosal mast cells. I. Isolation and functional characteristics of rat intestinal mast cells.

    A D Befus;F L Pearce;J Gauldie;P Horsewood

  • Cytokine expression by neutrophils and macrophages in vivo: endotoxin induces tumor necrosis factor-alpha, macrophage inflammatory protein-2, interleukin-1 beta, and interleukin-6 but not RANTES or transforming growth factor-beta 1 mRNA expression in acute lung inflammation.

    Zhou Xing;M. Jordana;H. Kirpalani;K. E. Driscoll

  • Regulation of secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (ESI/elafin) in human airway epithelial cells by cytokines and neutrophilic enzymes.

    Jean-Michel Sallenave;Jerry Shulmann;John Crossley;Manel Jordana

Frequent Co-Authors

Martin Kolb
Martin Kolb McMaster University
Manel Jordana
Manel Jordana McMaster University
Zhou Xing
Zhou Xing McMaster University
Frank L. Graham
Frank L. Graham McMaster University
Carl D. Richards
Carl D. Richards McMaster University
Yonghong Wan
Yonghong Wan McMaster University
Judah A. Denburg
Judah A. Denburg McMaster University
Jerry Dolovich
Jerry Dolovich McMaster University
Stephen M. Collins
Stephen M. Collins McMaster University
David Warburton
David Warburton University of Southern California

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