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Immunology

D-Index
52
Citations
7941
World Ranking
4094
National Ranking
105

Overview

Yonghong Wan is affiliated with McMaster University in Canada and has a research profile strongly focused on immunology, oncology, and molecular biology. The scientific work spans multiple interconnected disciplines, with notable contributions to medicine, immunology and microbiology, and biochemistry, genetics, and molecular biology.

Their main fields of study include:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Within these broad fields, Yonghong Wan's work covers several subfields, such as:

  • Immunology
  • Oncology
  • Molecular Biology
  • Genetics
  • Biomedical Engineering

The research topics addressed in their publications highlight a focus on advanced therapeutic strategies and immune mechanisms, including:

  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • Virus-based gene therapy research
  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction
  • Immune cells in cancer
  • SARS-CoV-2 and COVID-19 Research

Yonghong Wan has authored and coauthored multiple research papers in well-regarded scientific journals. Some recent papers include:

  • Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2, 2022, Cell
  • De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors, 2020, Communications Biology
  • Epigenetic modification of CSDE1 locus dictates immune recognition of nascent tumorigenic cells, 2023, Science Translational Medicine
  • Enhanced immunotherapeutic profile of oncolytic virus-based cancer vaccination using cyclophosphamide preconditioning, 2020, Journal for ImmunoTherapy of Cancer
  • Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells, 2021, Communications Biology

The frequent publication venues where Yonghong Wan has contributed include:

  • Communications Biology
  • Journal for ImmunoTherapy of Cancer
  • Cancers
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Immunology Research

The scientist's frequent coauthors include:

  • Karen Mossman
  • Scott R. Walsh
  • Nader El-Sayes
  • Samuel T. Workenhe
  • Jonathan L. Bramson

Best Publications

  • Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2

    Unknown

  • TNF-α is a critical negative regulator of type 1 immune activation during intracellular bacterial infection

    Anna Zganiacz;Michael Santosuosso;Jun Wang;Tony Yang

  • Potentiating Cancer Immunotherapy Using an Oncolytic Virus

    Byram W Bridle;Kyle B Stephenson;Jeanette E Boudreau;Sandeep Koshy

  • Maraba virus as a potent oncolytic vaccine vector.

    Jonathan G Pol;Liang Zhang;Byram W Bridle;Kyle B Stephenson

  • Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8+ T-cell memory development.

    Huafeng Zhang;Huafeng Zhang;Ke Tang;Jingwei Ma;Li Zhou

  • A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8+ T cells.

    Ruihua Ma;Tiantian Ji;Huafeng Zhang;Wenqian Dong

  • Dendritic cells transduced with an adenoviral vector encoding a model tumor-associated antigen for tumor vaccination.

    Yonghong Wan;Jonathan Bramson;Ronald Carter;Frank Graham

  • Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial

    A K Stewart;N J Lassam;I C Quirt;D J Bailey

  • Antigen Presentation by Exosomes Released from Peptide-Pulsed Dendritic Cells Is not Suppressed by the Presence of Active CTL

    Lea Luketic;Jordan Delanghe;Paul T. Sobol;Pingchang Yang

  • Enabling topical immunization via microporation: a novel method for pain-free and needle-free delivery of adenovirus-based vaccines.

    J Bramson;K Dayball;C Evelegh;Y H Wan

  • Phenotype, function, and in vivo migration and survival of allogeneic dendritic cell progenitors genetically engineered to express TGF-beta.

    Wei Cheng Lee;Cuiping Zhong;Shiguang Qian;Yonghong Wan

  • Engineering Dendritic Cells to Enhance Cancer Immunotherapy

    Jeanette E Boudreau;Aude Bonehill;Kris Thielemans;Yonghong Wan

  • Targeted Inhibition of Serotonin Type 7 (5-HT7) Receptor Function Modulates Immune Responses and Reduces the Severity of Intestinal Inflammation

    Janice J. Kim;Byram W. Bridle;Jean-Eric Ghia;Huaqing Wang

  • Cell-free Tumor Microparticle Vaccines Stimulate Dendritic Cells via cGAS/STING Signaling

    Huafeng Zhang;Ke Tang;Yi Zhang;Ruihua Ma

  • Molecular cloning, characterization, and tissue distribution of rat lipopolysaccharide binding protein. Evidence for extrahepatic expression.

    Grace L. Su;Paul D. Freeswick;David A. Geller;Qi Wang

  • The CD8+ T cell population elicited by recombinant adenovirus displays a novel partially exhausted phenotype associated with prolonged antigen presentation that nonetheless provides long-term immunity.

    Teng-Chih Yang;James Millar;Timothy Groves;Natalie Grinshtein

  • Vesicular Stomatitis Virus as a Novel Cancer Vaccine Vector to Prime Antitumor Immunity Amenable to Rapid Boosting With Adenovirus

    Byram W Bridle;Jeanette E Boudreau;Brian D Lichty;Jérôme Brunellière

  • Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models

    P.C.R. Emtage;Y. Wan;M. Hitt;F.L. Graham

  • HDAC Inhibition Suppresses Primary Immune Responses, Enhances Secondary Immune Responses, and Abrogates Autoimmunity During Tumor Immunotherapy

    Byram W Bridle;Lan Chen;Chantal G Lemay;Jean-Simon Diallo

  • Effects of stuffer DNA on transgene expression from helper-dependent adenovirus vectors.

    Robin J. Parks;Jonathan L. Bramson;Yonghong Wan;Christina L. Addison

  • Adaptive Antiviral Immunity Is a Determinant of the Therapeutic Success of Oncolytic Virotherapy

    Paul T Sobol;Jeanette E Boudreau;Kyle Stephenson;Yonghong Wan

Frequent Co-Authors

Jonathan L. Bramson
Jonathan L. Bramson McMaster University
Jack Gauldie
Jack Gauldie McMaster University
Brian D. Lichty
Brian D. Lichty McMaster University
Zhou Xing
Zhou Xing McMaster University
Frank L. Graham
Frank L. Graham McMaster University
John C. Bell
John C. Bell University of Ottawa
Angus W. Thomson
Angus W. Thomson University of Pittsburgh
Lina Lu
Lina Lu Cleveland Clinic Lerner College of Medicine
Shiguang Qian
Shiguang Qian Cleveland Clinic Lerner College of Medicine
Karen L. Mossman
Karen L. Mossman McMaster University

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