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Jonathan L. Bramson

Jonathan L. Bramson

D-Index & Metrics

Immunology

D-Index
61
Citations
10755
World Ranking
3272
National Ranking
82

Overview

Jonathan L. Bramson is affiliated with McMaster University in Canada and has contributed extensively to medical research, with a focus on oncology, immunology, and molecular biology. Their body of work represents a significant engagement with the study of immune cell function, cancer therapies, and infectious diseases.

The main fields of study associated with Jonathan L. Bramson include Medicine, with subfields such as Oncology, Immunology, Molecular Biology, Infectious Diseases, and Pulmonary and Respiratory Medicine. The research spans several key topics, notably:

  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • SARS-CoV-2 and COVID-19 Research
  • T-cell and B-cell Immunology
  • Viral Infectious Diseases and Gene Expression in Insects
  • Virus-based gene therapy research

Jonathan L. Bramson has published in several frequent venues, prominently including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cytotherapy
  • Regular and Young Investigator Award Abstracts
  • Journal of Clinical Oncology
  • OncoImmunology

Their recent papers demonstrate a range of topics within immunotherapy and oncology. Notable publications include:

  • "The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma," 2020, Cell Stem Cell
  • "Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors," 2021, iScience
  • "Metformin-induced reductions in tumor growth involves modulation of the gut microbiome," 2022, Molecular Metabolism
  • "De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors," 2020, Communications Biology
  • "The SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer response to radiotherapy," 2023, Communications Biology

Frequent collaborators in Jonathan L. Bramson's research projects include Joanne A. Hammill, Jessica A. Breznik, Dawn M. E. Bowdish, Ishac Nazy, and Andrew P. Costa. These coauthors have contributed to multiple publications, reflecting sustained research partnerships.

Best Publications

  • Interactions Between the Immune System and Cancer: A Brief Review of Non-spatial Mathematical Models

    Raluca Eftimie;Jonathan L. Bramson;David J. D. Earn

  • Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12

    J. L. Bramson;M. Hitt;C. L. Addison;W. J. Muller

  • TNF-α is a critical negative regulator of type 1 immune activation during intracellular bacterial infection

    Anna Zganiacz;Michael Santosuosso;Jun Wang;Tony Yang

  • Blood CD33(+)HLA-DR(−) myeloid-derived suppressor cells are increased with age and a history of cancer

    Chris P. Verschoor;Jennie Johnstone;Jamie Millar;Michael G. Dorrington

  • IL-12 gene therapy protects mice in lethal Klebsiella pneumonia.

    M J Greenberger;S L Kunkel;R M Strieter;N W Lukacs

  • A Human Type 5 Adenovirus–Based Tuberculosis Vaccine Induces Robust T Cell Responses in Humans Despite Preexisting Anti-Adenovirus Immunity

    Fiona Smaill;Mangalakumari Jeyanathan;Marek Smieja;Maria Fe Medina

  • Induction of Epitope-Specific Neutralizing Antibodies against West Nile Virus

    Theodore Oliphant;Grant E. Nybakken;S. Kyle Austin;Qing Xu

  • Potentiating Cancer Immunotherapy Using an Oncolytic Virus

    Byram W Bridle;Kyle B Stephenson;Jeanette E Boudreau;Sandeep Koshy

  • Maraba virus as a potent oncolytic vaccine vector.

    Jonathan G Pol;Liang Zhang;Byram W Bridle;Kyle B Stephenson

  • Dendritic cells transduced with an adenoviral vector encoding a model tumor-associated antigen for tumor vaccination.

    Yonghong Wan;Jonathan Bramson;Ronald Carter;Frank Graham

  • Defining the critical hurdles in cancer immunotherapy

    Bernard A. Fox;Bernard A. Fox;Dolores J. Schendel;Lisa H. Butterfield;Steinar Aamdal

  • The use of adenoviral vectors for gene therapy and gene transfer in vivo

    Jonathan L Bramson;Frank L Graham;Jack Gauldie

  • Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen presenting cell properties

    Moïra François;Moïra François;Raphaëlle Romieu-Mourez;Sophie Stock-Martineau;Marie Noëlle Boivin

  • Antigen Presentation by Exosomes Released from Peptide-Pulsed Dendritic Cells Is not Suppressed by the Presence of Active CTL

    Lea Luketic;Jordan Delanghe;Paul T. Sobol;Pingchang Yang

  • The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma.

    Parvez Vora;Chitra Venugopal;Sabra Khalid Salim;Nazanin Tatari

  • IL-1α/IL-1R1 Expression in Chronic Obstructive Pulmonary Disease and Mechanistic Relevance to Smoke-Induced Neutrophilia in Mice

    Fernando M. Botelho;Carla M. T. Bauer;Donna Finch;Jake K. Nikota

  • A Switch in Costimulation from CD28 to 4-1BB during Primary versus Secondary CD8 T Cell Response to Influenza In Vivo

    Edward M. Bertram;Wojciech Dawicki;Bradley Sedgmen;Jonathan L. Bramson

  • Enabling topical immunization via microporation: a novel method for pain-free and needle-free delivery of adenovirus-based vaccines.

    J Bramson;K Dayball;C Evelegh;Y H Wan

  • Construction of a double recombinant adenovirus vector expressing a heterodimeric cytokine: in vitro and in vivo production of biologically active interleukin-12.

    J. Bramson;M. Hitt;W. S. Gallichan;K. L. Rosenthal

  • Pre-existing immunity to adenovirus does not prevent tumor regression following intratumoral administration of a vector expressing IL-12 but inhibits virus dissemination

    JL Bramson;M Hitt;J Gauldie;FL Graham

Frequent Co-Authors

Yonghong Wan
Yonghong Wan McMaster University
Mark Loeb
Mark Loeb McMaster University
Brian D. Lichty
Brian D. Lichty McMaster University
Zhou Xing
Zhou Xing McMaster University
Jack Gauldie
Jack Gauldie McMaster University
Dawn M. E. Bowdish
Dawn M. E. Bowdish McMaster University
Frank L. Graham
Frank L. Graham McMaster University
Ali A. Ashkar
Ali A. Ashkar McMaster University
Jeffrey A. Medin
Jeffrey A. Medin Medical College of Wisconsin
Jason Moffat
Jason Moffat University of Toronto

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