World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
9120
World Ranking
17998
National Ranking
7365

Overview

Jeffrey A. Medin is affiliated with the Medical College of Wisconsin in the United States. Their research spans several fields, primarily focused on medicine and biochemistry, genetics, and molecular biology. Within these broad areas, research subfields include molecular biology, physiology, genetics, oncology, and epidemiology.

The scientist's work addresses various topics, including lysosomal storage disorders research, CAR-T cell therapy research, sphingolipid metabolism and signaling, virus-based gene therapy research, cytomegalovirus and herpesvirus research, CRISPR and genetic engineering, and adenosine and purinergic signaling.

Jeffrey A. Medin has published extensively in venues such as:

  • Molecular Genetics and Metabolism
  • Molecular Therapy
  • Frontiers in Immunology
  • Nature Communications
  • Science Advances

Recent papers by the scientist include:

  • "Lentivirus-mediated gene therapy for Fabry disease," 2021, Nature Communications
  • "Targeting oncoproteins with a positive selection assay for protein degraders," 2021, Science Advances
  • "Gene therapy for Fabry disease: Progress, challenges, and outlooks on gene-editing," 2021, Molecular Genetics and Metabolism
  • "Sarcoma IL-12 overexpression facilitates NK cell immunomodulation," 2021, Scientific Reports
  • "Discovery and validation of surface N-glycoproteins in MM cell lines and patient samples uncovers immunotherapy targets," 2020, Journal for ImmunoTherapy of Cancer

Frequent collaborators with this scientist include William M. McKillop, Michael L. West, Mary L. Faber, Dwayne L. Barber, and Armand Keating. These coauthors have contributed to multiple publications alongside the scientist.

Best Publications

  • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

    Hansjorg Keller;Christine Dreyer;Jeffrey Medin;Abderrahim Mahfoudi

  • The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.

    Shoba Amarnath;Courtney W. Mangus;Courtney W. Mangus;James C. M. Wang;Fang Wei

  • Functional Repair of Human Donor Lungs by IL-10 Gene Therapy

    Marcelo Cypel;Marcelo Cypel;Mingyao Liu;Mingyao Liu;Matt Rubacha;Jonathan C. Yeung;Jonathan C. Yeung

  • Molecular interactions between interferon consensus sequence binding protein and members of the interferon regulatory factor family

    C Bovolenta;P H Driggers;M S Marks;J A Medin

  • Strategies for Delaying or Treating In vivo Acquired Resistance to Trastuzumab in Human Breast Cancer Xenografts

    Jeanne M. du Manoir;Giulio Francia;Shan Man;Miriam Mossoba

  • A neutral sphingomyelinase resides in sphingolipid-enriched microdomains and is inhibited by the caveolin-scaffolding domain: potential implications in tumour necrosis factor signalling.

    Robert J. Veldman;Nicolas Maestre;Osama M. Aduib;Jeffrey A. Medin

  • RETINOID X RECEPTOR AND PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ACTIVATE AN ESTROGEN RESPONSIVE GENE INDEPENDENT OF THE ESTROGEN RECEPTOR

    Susan B Nuñez;Jeffrey A Medin;Olivier Braissant;Lawrence Kemp

  • XENOPUS PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS: GENOMIC ORGANIZATION, RESPONSE ELEMENT RECOGNITION, HETERODIMER FORMATION WITH RETINOID X RECEPTOR AND ACTIVATION BY FATTY ACIDS

    Grigorios Krey;Hansjörg Keller;Abderrahim Mahfoudi;Jeffrey Medin

  • Stem cell factor receptor induces progenitor and natural killer cell-mediated cardiac survival and repair after myocardial infarction

    Bilal B. Ayach;Makoto Yoshimitsu;Fayez Dawood;Mei Sun

  • Acid ceramidase deficiency: Farber disease and SMA-PME

    Fabian P. S. Yu;Samuel Amintas;Thierry Levade;Jeffrey A. Medin

  • Engineered human tmpk/AZT as a novel enzyme/prodrug axis for suicide gene therapy.

    Takeya Sato;Anton Neschadim;Anton Neschadim;Manfred Konrad;Daniel H Fowler

  • Isolation of cell surface proteins for mass spectrometry-based proteomics.

    Sarah Elschenbroich;Yunee Kim;Jeffrey A Medin;Thomas Kislinger

  • Efficient, low-cost protein factories: expression of human adenosine deaminase in baculovirus-infected insect larvae

    Jeffrey A. Medin;Laura Hunt;Karen Gathy;Robert K. Evans

  • Bioluminescent imaging of a marking transgene and correction of Fabry mice by neonatal injection of recombinant lentiviral vectors

    Makoto Yoshimitsu;Takeya Sato;Kesheng Tao;Jagdeep S. Walia

  • Long-term enzyme correction and lipid reduction in multiple organs of primary and secondary transplanted Fabry mice receiving transduced bone marrow cells.

    Toshihiro Takenaka;Gary J. Murray;Gangjian Qin;Jane M. Quirk

  • Peroxisome Proliferator-Activated Receptors and Lipid Metabolism

    Hansjörg Keller;Abderrahim Mahfoudi;Christine Dreyer;Abdelmadjid K. Hihi

  • H2 relaxin overexpression increases in vivo prostate xenograft tumor growth and angiogenesis

    Josh D. Silvertown;Jonathan Ng;Takeya Sato;Alastair J. Summerlee

  • Paracrine effects of transplanted myoblasts and relaxin on post-infarction heart remodelling.

    Lucia Formigli;Avio-Maria Perna;Elisabetta Meacci;Lorenzo Cinci

  • Systemic ceramide accumulation leads to severe and varied pathological consequences

    Abdulfatah M. Alayoubi;Abdulfatah M. Alayoubi;James C. M. Wang;Bryan C. Y. Au;Stéphane Carpentier

  • Correction in trans for Fabry disease: expression, secretion and uptake of alpha-galactosidase A in patient-derived cells driven by a high-titer recombinant retroviral vector

    Jeffrey A. Medin;Matthew Tudor;Ryan Simovitch;Jane M. Quirk

Frequent Co-Authors

Christopher J. Paige
Christopher J. Paige Princess Margaret Cancer Centre
Thierry Levade
Thierry Levade Paul Sabatier University
Armand Keating
Armand Keating University of Toronto
Roscoe O. Brady
Roscoe O. Brady Beth Israel Deaconess Medical Center
Shaf Keshavjee
Shaf Keshavjee University Health Network
Mingyao Liu
Mingyao Liu University Health Network
Keiko Ozato
Keiko Ozato Eunice Kennedy Shriver National Institute of Child Health and Human Development
Thomas Kislinger
Thomas Kislinger University of Toronto
Stefan Karlsson
Stefan Karlsson Lund University
William G. Kaelin
William G. Kaelin Harvard University

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