World's Best Scientists 2026 revealed!
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Frank J. Gonzalez
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Best Scientists
2025
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Biology and Biochemistry
USA
2026

D-Index & Metrics

Best Scientists

D-Index
210
Citations
165749
World Ranking
199
National Ranking
131

Biology and Biochemistry

D-Index
213
Citations
171964
World Ranking
24
National Ranking
21

Medicine

D-Index
213
Citations
172052
World Ranking
120
National Ranking
81

Frank J. Gonzalez publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Frank J. Gonzalez sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 1,349 publications — 100th percentile

100% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Frank J. Gonzalez D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Frank J. Gonzalez sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 213 D-Index — 100th percentile

100% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2026 - Research.com Medicine in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Medicine in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award

Overview

Frank J. Gonzalez is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, encompassing 256 and 200 publications respectively. Within these domains, they have focused extensively on subfields such as Molecular Biology, Epidemiology, Oncology, Pharmacology, and Physiology.

The main research topics addressed by Gonzalez include:

  • Liver Disease Diagnosis and Treatment
  • Peroxisome Proliferator-Activated Receptors
  • Drug Transport and Resistance Mechanisms
  • Cancer, Hypoxia, and Metabolism
  • Gut microbiota and health
  • Diet, Metabolism, and Disease
  • Pharmacogenetics and Drug Metabolism

Gonzalez has published across a range of scientific venues, with frequent contributions to:

  • Value in Health
  • Nature Communications
  • The FASEB Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Hepatology

Some recent publications by Gonzalez include:

  • Gut microbiota-derived bile acids in intestinal immunity, inflammation, and tumorigenesis, 2022, Cell Host & Microbe
  • PPARs as Metabolic Regulators in the Liver: Lessons from Liver-Specific PPAR-Null Mice, 2020, International Journal of Molecular Sciences
  • The role of farnesoid X receptor in metabolic diseases, and gastrointestinal and liver cancer, 2021, Nature Reviews Gastroenterology & Hepatology
  • Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice, 2023, Nature Communications
  • Gut bacteria alleviate smoking-related NASH by degrading gut nicotine, 2022, Nature

Frequent coauthors in Gonzalez's research include:

  • Kristopher W. Krausz
  • Shogo Takahashi
  • Lulu Sun
  • Yuhong Luo
  • Cen Xie

Best Publications

  • Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

    Sander Kersten;Josiane Seydoux;Jeffrey M. Peters;Frank J. Gonzalez

  • Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis

    Christopher J Sinal;Masahiro Tohkin;Masaaki Miyata;Jerrold M Ward

  • C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway.

    Evan D. Rosen;Chung-Hsin Hsu;Xinzhong Wang;Shuichi Sakai

  • Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

    Huafeng Zhang;Marta Bosch-Marce;Larissa A. Shimoda;Yee Sun Tan

  • The PPARalpha-leukotriene B4 pathway to inflammation control.

    Pallavi R. Devchand;Hansjörg Keller;Jeffrey Maurice Peters;Manuel Vazquez

  • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators.

    S S Lee;T Pineau;J Drago;E J Lee

  • Role of Aryl Hydrocarbon Receptor-mediated Induction of the CYP1 Enzymes in Environmental Toxicity and Cancer

    Daniel W. Nebert;Timothy P. Dalton;Allan B. Okey;Frank J. Gonzalez

  • Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

    Pedro Fernandez-Salguero;Thierry Pineau;David M. Hilbert;Timothy McPhail

  • Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

    Philippe Delerive;Karolien De Bosscher;Sandrine Besnard;Wim Vanden Berghe

  • Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis.

    Graham P. Hayhurst;Ying-Hue Lee;Gilles Lambert;Jerrold M. Ward

  • International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors

    Liliane Michalik;Johan Auwerx;Joel P. Berger;V. Krishna Chatterjee

  • Altered Constitutive Expression of Fatty Acid-metabolizing Enzymes in Mice Lacking the Peroxisome Proliferator-activated Receptor α (PPARα)

    Toshifumi Aoyama;Jeffrey M. Peters;Nobuko Iritani;Tamie Nakajima

  • Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity

    Pedro M. Fernandez-Salguero;David M. Hilbert;Stuart Rudikoff;Jerrold M. Ward

  • CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

    Isabelle A. Leclercq;Geoffrey C. Farrell;Jaqueline Field;David R. Bell

  • Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.

    F J Gonzalez;R C Skoda;S Kimura;M Umeno

  • Liver Peroxisome Proliferator-activated Receptor γ Contributes to Hepatic Steatosis, Triglyceride Clearance, and Regulation of Body Fat Mass

    Oksana Gavrilova;Martin Haluzik;Kimihiko Matsusue;Jaime J. Cutson

  • The P450 Superfamily: Updated Listing of All Genes and Recommended Nomenclature for the Chromosomal Loci

    Daniel W. Nebert;David R. Nelson;Milton Adesnik;Minor J. Coon

  • Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

    Yanqiao Zhang;Florence Ying Lee;Gabriel Barrera;Hans Lee

  • Regulation of hepatic fasting response by PPARγ coactivator-1α (PGC-1): Requirement for hepatocyte nuclear factor 4α in gluconeogenesis

    James Rhee;Yusuke Inoue;J. Cliff Yoon;Pere Puigserver

  • Gut microbiota and intestinal FXR mediate the clinical benefits of metformin.

    Lulu Sun;Cen Xie;Guang Wang;Yue Wu

Frequent Co-Authors

Kristopher W. Krausz
Kristopher W. Krausz National Institutes of Health
Jeffrey M. Peters
Jeffrey M. Peters Pennsylvania State University
Jeffrey R. Idle
Jeffrey R. Idle University of Bern
Harry V. Gelboin
Harry V. Gelboin National Institutes of Health
Andrew D. Patterson
Andrew D. Patterson Pennsylvania State University
Yatrik M. Shah
Yatrik M. Shah University of Michigan–Ann Arbor
Shioko Kimura
Shioko Kimura National Institutes of Health
Pedro M. Fernandez-Salguero
Pedro M. Fernandez-Salguero University of Extremadura
Daniel W. Nebert
Daniel W. Nebert University of Cincinnati
Jerrold M. Ward
Jerrold M. Ward National Institutes of Health

External Links

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