2026 Jeffrey R. Idle: Medicine Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Medicine	88	13270	12491	188	181	321	25214

Overview

Jeffrey R. Idle is affiliated with the University of Bern in Switzerland. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several significant subfields including Molecular Biology, Epidemiology, Physiology, Pharmacology, and Pathology and Forensic Medicine.

The main topics addressed in their work include:

Liver Disease Diagnosis and Treatment
Metabolomics and Mass Spectrometry Studies
Diet and metabolism studies
Drug-Induced Hepatotoxicity and Protection
Gut microbiota and health
Chemotherapy-induced organ toxicity mitigation
Cancer, Hypoxia, and Metabolism

Jeffrey R. Idle has contributed to a number of publications across well-known venues, frequently publishing in:

International Journal of Molecular Sciences
Cancers
Biochemical Pharmacology
Scientific Reports
Cells

Their recent papers include:

"Metabolomic and Lipidomic Biomarkers for Premalignant Liver Disease Diagnosis and Therapy," 2020, Metabolites
"Metabolic Rewiring and the Characterization of Oncometabolites," 2021, Cancers
"Ifosfamide - History, efficacy, toxicity and encephalopathy," 2023, Pharmacology & Therapeutics
"Metabolomic insights into the mode of action of natural products in the treatment of liver disease," 2020, Biochemical Pharmacology
"Consumption of Grapes Modulates Gene Expression, Reduces Non-Alcoholic Fatty Liver Disease, and Extends Longevity in Female C57BL/6J Mice Provided with a High-Fat Western-Pattern Diet," 2022, Foods

Frequent coauthors collaborating with Jeffrey R. Idle include:

Diren Beyoğlu
Asim Dave
John M. Pezzuto
Yury Popov
Eun-Jung Park

Best Publications

Polymorphic hydroxylation of debrisoquine in man

A Mahgoub;L.G Dring;J.R Idle;R Lancaster

1686
Citations
A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

D A Evans;A Mahgoub;T P Sloan;J R Idle

783
Citations
Nomenclature for human CYP2D6 alleles.

A K Daly;J Brockmoller;F Broly;M Eichelbaum

590
Citations
Metabolic oxidation phenotypes as markers for susceptibility to lung cancer

Riad Ayesh;Jeffrey R. Idle;James C. Ritchie;Michael J. Crothers

531
Citations
Drug Transporters in Drug Efficacy and Toxicity

M K DeGorter;C Q Xia;J J Yang;R B Kim

394
Citations
Metabolism of melatonin by human cytochromes p450.

Xiaochao Ma;Jeffrey R Idle;Kristopher W Krausz;Frank J Gonzalez

389
Citations
The role of individual human cytochromes P450 in drug metabolism and clinical response.

Suzanne Cholerton;Ann K. Daly;Jeffrey R. Idle

378
Citations
Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy.

Hirokazu Furuya;Pedro Fernandez-salguero;Wendy Gregory;Heather Taber

351
Citations
Mutant debrisoquine hydroxylation genes in Parkinson's disease

M. Armstrong;A.K. Daly;S. Cholerton;J.R. Idle

338
Citations
LC-MS-based metabolomics in drug metabolism.

Chi Chen;Frank J. Gonzalez;Jeffrey R. Idle

305
Citations
Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology

Vidar M. Steen;Ole A. Andreassen;Ann K. Daly;Toril Tefre

303
Citations
Impaired oxidation of debrisoquine in patients with perhexiline neuropathy.

R R Shah;N S Oates;J R Idle;R L Smith

289
Citations
Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling.

Andrew D. Patterson;Olivier Maurhofer;Diren Beyoğlu;Christian Lanz

286
Citations
CYP2E1 Genetic Polymorphisms and Risk of Nasopharyngeal Carcinoma in Taiwan

Allan Hildesheim;Lucy M. Anderson;Chien-Jen Chen;Yu-Juen Cheng

283
Citations
Pharmacogenetic phenotyping and genotyping. Present status and future potential.

Frank J. Gonzalez;Frank J. Gonzalez;Jeffrey R. Idle;Jeffrey R. Idle

282
Citations
Xenobiotic metabolomics: major impact on the metabolome.

Caroline H. Johnson;Andrew D. Patterson;Jeffrey R. Idle;Frank J. Gonzalez

268
Citations
The metabolomic window into hepatobiliary disease

Diren Beyoğlu;Jeffrey R. Idle

268
Citations
Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene

Roger Løvlie;Ann K. Daly;Anders Molven;Jeffrey R. Idle;Jeffrey R. Idle

253
Citations
Tissue metabolomics of hepatocellular carcinoma: Tumor energy metabolism and the role of transcriptomic classification†‡

Diren Beyoğlu;Sandrine Imbeaud;Sandrine Imbeaud;Olivier Maurhofer;Paulette Bioulac-Sage

252
Citations
Human P450PCN1: sequence, chromosome localization, and direct evidence through cDNA expression that P450PCN1 is nifedipine oxidase.

Frank J. Gonzalez;Balthazar J. Schmid;Morio Umeno;O. Wesley Mcbride

242
Citations

Frequent Co-Authors

Frank J. Gonzalez National Institutes of Health

Robert L. Smith Imperial College London

Kristopher W. Krausz National Institutes of Health

Ann K. Daly Newcastle University

Andrew D. Patterson Pennsylvania State University

Chi Chen University of Minnesota

Stephanie J. London National Institutes of Health

Yatrik M. Shah University of Michigan–Ann Arbor

R. T. Williams Imperial College London

Neil E. Caporaso National Institutes of Health

External Links

Personal website of Jeffrey R. Idle

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