D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 83 Citations 21,531 271 World Ranking 10598 National Ranking 159

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

The scientist’s investigation covers issues in Debrisoquine, Internal medicine, Pharmacology, Genetics and Biochemistry. His studies in Debrisoquine integrate themes in fields like Debrisoquin, Polymorphism and Hydroxylation. The concepts of his Internal medicine study are interwoven with issues in Gastroenterology, Endocrinology and Pathology.

His work on Acetaminophen as part of general Pharmacology research is frequently linked to In patient, bridging the gap between disciplines. His Genetics research focuses on Molecular biology and how it connects with Humanized mouse, Peptide sequence and COS cells. His research investigates the link between Biochemistry and topics such as Metabolomics that cross with problems in Transcriptome, Lipid metabolism, Toxicity and Physiology.

His most cited work include:

  • Polymorphic hydroxylation of debrisoquine in man (1048 citations)
  • A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population. (503 citations)
  • Nomenclature for human CYP2D6 alleles. (355 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Pharmacology, Internal medicine, Endocrinology, Biochemistry and Metabolite. Jeffrey R. Idle has included themes like Metabolism, Toxicity, Debrisoquine and Hydroxylation in his Pharmacology study. Jeffrey R. Idle usually deals with Debrisoquine and limits it to topics linked to Allele and Genotype, Restriction fragment length polymorphism and Genotyping.

His Internal medicine research is multidisciplinary, incorporating perspectives in Pharmacogenetics and Oncology. He interconnects Peroxisome proliferator-activated receptor, Trimethylamine and Nicotine in the investigation of issues within Endocrinology. His Metabolite study incorporates themes from Urine, Chromatography and Nifedipine.

He most often published in these fields:

  • Pharmacology (36.54%)
  • Internal medicine (33.55%)
  • Endocrinology (28.90%)

What were the highlights of his more recent work (between 2006-2021)?

  • Metabolomics (20.27%)
  • Biochemistry (25.58%)
  • Pharmacology (36.54%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Metabolomics, Biochemistry, Pharmacology, Internal medicine and Endocrinology. His Metabolomics research incorporates themes from Metabolite, Urine, Tandem mass spectrometry and Xenobiotic. His study looks at the relationship between Metabolite and fields such as Metabolism, as well as how they intersect with chemical problems.

His Pharmacology research integrates issues from Pregnane X receptor and Toxicity. Internal medicine is frequently linked to Gastroenterology in his study. His Endocrinology research incorporates elements of Biomarker, Peroxisome proliferator-activated receptor, Fatty acid, Liver disease and Peroxisome.

Between 2006 and 2021, his most popular works were:

  • Aberrant Lipid Metabolism in Hepatocellular Carcinoma Revealed by Plasma Metabolomics and Lipid Profiling (189 citations)
  • LC-MS-based metabolomics in drug metabolism. (179 citations)
  • Xenobiotic metabolomics: major impact on the metabolome. (139 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Metabolomics, Biochemistry, Pharmacology, Internal medicine and Metabolite are his primary areas of study. Jeffrey R. Idle combines subjects such as Pimelic acid, Urine, Xanthine and Metabolism with his study of Metabolomics. His biological study spans a wide range of topics, including Tandem mass spectrometry and Mass spectrometry.

His studies deal with areas such as Pregnane X receptor and Toxicity as well as Pharmacology. His Internal medicine research includes themes of Gastroenterology and Endocrinology. Jeffrey R. Idle has researched Drug metabolism in several fields, including Phenacetin, Polymorphism, Debrisoquine, Hydroxylation and Xenobiotic.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Polymorphic hydroxylation of debrisoquine in man

A Mahgoub;L.G Dring;J.R Idle;R Lancaster.
The Lancet (1977)

1667 Citations

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

D A Evans;A Mahgoub;T P Sloan;J R Idle.
Journal of Medical Genetics (1980)

777 Citations

Nomenclature for human CYP2D6 alleles.

A K Daly;J Brockmoller;F Broly;M Eichelbaum.
Pharmacogenetics (1996)

583 Citations

Metabolic oxidation phenotypes as markers for susceptibility to lung cancer

Riad Ayesh;Jeffrey R. Idle;James C. Ritchie;Michael J. Crothers.
Nature (1984)

532 Citations

The role of individual human cytochromes P450 in drug metabolism and clinical response.

Suzanne Cholerton;Ann K. Daly;Jeffrey R. Idle.
Trends in Pharmacological Sciences (1992)

373 Citations

Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy.

Hirokazu Furuya;Pedro Fernandez-salguero;Wendy Gregory;Heather Taber.
Pharmacogenetics (1995)

347 Citations

Metabolism of melatonin by human cytochromes p450.

Xiaochao Ma;Jeffrey R Idle;Kristopher W Krausz;Frank J Gonzalez.
Drug Metabolism and Disposition (2005)

341 Citations

Mutant debrisoquine hydroxylation genes in Parkinson's disease

M. Armstrong;A.K. Daly;S. Cholerton;J.R. Idle.
The Lancet (1992)

338 Citations

Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology

Vidar M. Steen;Ole A. Andreassen;Ann K. Daly;Toril Tefre.
Pharmacogenetics (1995)

300 Citations

Impaired oxidation of debrisoquine in patients with perhexiline neuropathy.

R R Shah;N S Oates;J R Idle;R L Smith.
BMJ (1982)

286 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Jeffrey R. Idle

Frank J. Gonzalez

Frank J. Gonzalez

National Institutes of Health

Publications: 163

Ann K. Daly

Ann K. Daly

Newcastle University

Publications: 65

Albert J. Fornace

Albert J. Fornace

Georgetown University

Publications: 59

Rachel F. Tyndale

Rachel F. Tyndale

University of Toronto

Publications: 59

F. Peter Guengerich

F. Peter Guengerich

Vanderbilt University

Publications: 58

Michel Eichelbaum

Michel Eichelbaum

University of Tübingen

Publications: 58

Leif Bertilsson

Leif Bertilsson

Karolinska University Hospital

Publications: 57

Kristopher W. Krausz

Kristopher W. Krausz

National Institutes of Health

Publications: 57

Daniel W. Nebert

Daniel W. Nebert

University of Cincinnati

Publications: 53

Magnus Ingelman-Sundberg

Magnus Ingelman-Sundberg

Karolinska Institute

Publications: 45

Jürgen Brockmöller

Jürgen Brockmöller

University of Göttingen

Publications: 42

Marja-Liisa Dahl

Marja-Liisa Dahl

Karolinska University Hospital

Publications: 42

Tetsuya Kamataki

Tetsuya Kamataki

Hokkaido University

Publications: 37

Kim Brøsen

Kim Brøsen

University of Southern Denmark

Publications: 36

Ivar Roots

Ivar Roots

Charité - University Medicine Berlin

Publications: 33

Andrew D. Patterson

Andrew D. Patterson

Pennsylvania State University

Publications: 31

Trending Scientists

Huiling Chen

Huiling Chen

Wenzhou University

Patrick Chiu

Patrick Chiu

FX Palo Alto Laboratory

Hilbert J. Kappen

Hilbert J. Kappen

Radboud University Nijmegen

Tomoyuki Okada

Tomoyuki Okada

Panasonic (Japan)

Anders Mikkelsen

Anders Mikkelsen

Lund University

Ivar Rønnestad

Ivar Rønnestad

University of Bergen

Clifford A. Lowell

Clifford A. Lowell

University of California, San Francisco

Lu-Hai Wang

Lu-Hai Wang

National Health Research Institutes

Rejko Krüger

Rejko Krüger

University of Luxembourg

Petra C. F. Oyston

Petra C. F. Oyston

Defence Science and Technology Laboratory

Nigel T. Maidment

Nigel T. Maidment

University of California, Los Angeles

Christel M. Middeldorp

Christel M. Middeldorp

University of Queensland

Hiromi Rakugi

Hiromi Rakugi

Osaka University

Kjetil Søreide

Kjetil Søreide

Stavanger University Hospital

Philip A. Kern

Philip A. Kern

University of Kentucky

Eugenio Mercuri

Eugenio Mercuri

Catholic University of the Sacred Heart

Something went wrong. Please try again later.