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Chemistry

D-Index
63
Citations
12469
World Ranking
8542
National Ranking
484

Overview

R. T. Williams is affiliated with Imperial College London in the United Kingdom. Their research spans multiple disciplines primarily within biochemistry, genetics, molecular biology, and medicine. The scientist's scholarly output includes a focus on molecular biology, materials chemistry, biomedical engineering, nephrology, and biomaterials.

The primary topics of research in Williams's work encompass advanced biosensing and bioanalysis techniques, carbon nanotubes in composites, advanced biosensing techniques and applications, nanoparticle-based drug delivery, graphene and nanomaterials applications, acute kidney injury research, and analytical chemistry and sensors.

Williams has contributed to publications in the following venues:

  • ECS Meeting Abstracts
  • Journal of the American Society of Nephrology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation Research
  • Kidney International

Recent papers authored or co-authored by Williams include:

  • Selective nanoparticle-mediated targeting of renal tubular Toll-like receptor 9 attenuates ischemic acute kidney injury, 2020, Kidney International
  • Kidney-Targeted Renalase Agonist Prevents Cisplatin-Induced Chronic Kidney Disease by Inhibiting Regulated Necrosis and Inflammation, 2021, Journal of the American Society of Nephrology
  • Tubular IL-1β Induces Salt Sensitivity in Diabetes by Activating Renal Macrophages, 2022, Circulation Research
  • The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension, 2022, Circulation Research
  • Glutathione-S-transferase Fusion Protein Nanosensor, 2020, Nano Letters

Frequent collaborators in Williams's research include:

  • Daniel A. Heller
  • Zachary Cohen
  • Edgar A. Jaimes
  • Amelia K. Ryan
  • Pooja Vinod Gaikwad

The combination of fields and topics illustrates an intersection of biochemistry and molecular biology with materials science and engineering approaches, notably for applications relevant to kidney disease and biosensing technologies. The involvement in nephrology and acute kidney injury research suggests attention to clinically relevant biomedical challenges, while work on nanomaterial-based sensing and delivery platforms highlights an emphasis on technological innovation.

Best Publications

  • Metabolism of [14C]methamphetamine in man, the guinea pig and the rat

    J. Caldwell;L. G. Dring;R. T. Williams

  • The metabolic fate of amphetamine in man and other species.

    L. G. Dring;R. L. Smith;R. T. Williams

  • A fluorimetric study of the hydroxylation of biphenyl in vitro by liver preparations of various species

    PJ Creaven;DV Parke;RT Williams

  • Studies in detoxication. 67. The biosynthesis of the glucuronides of umbelliferone and 4-methylumbelliferone and their use in fluorimetric determination of β-glucuronidase

    J. A. R. Mead;J. N. Smith;R. T. Williams

  • The fate of benzoic acid in various species

    J. W. Bridges;M. R. French;R. L. Smith;R. T. Williams

  • The conjugation of phenylacetic acid in man, sub-human primates and some non-primate species.

    Margaret O. James;R. L. Smith;Richard Tecwyn Williams;M. Reidenberg

  • Species variations in the threshold molecular-weight factor for the biliary excretion of organic anions.

    P. C. Hirom;P. Millburn;R. L. Smith;R. T. Williams

  • Toxicity and Teratogenicity of Optical Isomers of Thalidomide

    S Fabro;R L Smith;R T Williams

  • Biliary excretion of foreign compounds. Biphenyl, stilboestrol and phenolphthalein in the rat: molecular weight, polarity and metabolism as factors in biliary excretion.

    P Millburn;R L Smith;R T Williams

  • The fate of (14C)phenol in various species.

    I. D. Capel;M. R. French;P. Millburn;R. L. Smith

  • Studies in detoxication. 49. The metabolism of benzene containing [14C1]benzene

    D. V. Parke;R. T. Williams

  • THE INFLUENCE OF ENTEROHEPATIC CIRCULATION ON TOXICITY OF DRUGS.

    R. T. Williams;P. Millburn;R. L. Smith

  • Studies in detoxication. 86. The metabolism of 14C-labelled ethylene glycol.

    P. K. Gessner;D. V. Parke;R. T. Williams

  • Inter-Species Variations in the Metabolism of Xenobiotics

    R. T. Williams

  • Studies in detoxication. 81. The metabolism of halogenobenzenes: (a) Penta- and hexa-chlorobenzenes. (b) Further observations on 1:3:5-trichlorobenzene.

    D V Parke;R T Williams

  • The metabolism of thalidomide: the spontaneous hydrolysis of thalidomide in solution.

    H. Schumacher;R. L. Smith;R. T. Williams

  • Studies in detoxication. 69. The metabolism of alkylbenzenes: n-propylbenzene and n-butylbenzene with further observations on ethylbenzene

    A. M. El Masry;J. N. Smith;R. T. Williams

  • The fluorescence of indoles and aniline derivatives.

    J W Bridges;R T Williams

  • The metabolism of thalidomide: the fate of thalidomide and some of its hydrolysis products in various species.

    H. Schumacher;R. L. Smith;R. T. Williams

  • The Role of the Gut Flora in the Metabolism of Prontosil and Neoprontosil in the Rat

    R Gingell;J W Bridges;R T Williams

  • Fluorescence studies on some hydroxypyridines including compounds of the vitamin B6 group.

    JW Bridges;DS Davies;RT Williams

  • A Spectrofluorimetric study of the 7-hydroxylation of coumarin by liver microsomes

    PJ Creaven;DV Parke;RT Williams

  • The fate of amphetamine in man and other mammals

    L G Dring;R L Smith;R T Williams

Frequent Co-Authors

Robert L. Smith
Robert L. Smith Imperial College London
Jeffrey R. Idle
Jeffrey R. Idle University of Bern
Peter S. Sever
Peter S. Sever Imperial College London

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