What is he best known for?
The fields of study he is best known for:
- Enzyme
- Biochemistry
- Metabolism
His scientific interests lie mostly in Biochemistry, Cytochrome P450, Cytochrome, Carcinogen and Metabolism.
His work on Biochemistry is being expanded to include thematically relevant topics such as Pharmacology.
His biological study spans a wide range of topics, including Isothiocyanate, Enzyme inducer and Sulforaphane.
His Cytochrome P450 research incorporates themes from Xenobiotic and Toxicity.
The concepts of his Cytochrome study are interwoven with issues in Imidazole, Stereochemistry, Active site, Molecule and Substrate.
His work carried out in the field of Carcinogen brings together such families of science as Drug metabolizing enzymes, Toxicology, Reactive intermediate, Detoxication and Ames test.
His most cited work include:
- Interaction of a series of nitriles with the alcohol-inducible isoform of P450: Computer analysis of structure—activity relationships (342 citations)
- The cytochrome P450 I gene family of microsomal hemoproteins and their role in the metabolic activation of chemicals. (212 citations)
- Mechanism of induction of hepatic microsomal drug metabolizing enzymes by a series of barbiturates. (140 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Biochemistry, Cytochrome P450, Microsome, Carcinogen and Cytochrome.
Biochemistry and Ames test are frequently intertwined in his study.
His Cytochrome P450 study combines topics in areas such as Isozyme, Toxicity and Hydroxylation.
Costas Ioannides combines subjects such as Oxidase test, Pharmacology and Hamster with his study of Microsome.
He studied Carcinogen and Metabolism that intersect with In vitro.
The study incorporates disciplines such as Reactive intermediate and Stereochemistry in addition to Cytochrome.
He most often published in these fields:
- Biochemistry (53.28%)
- Cytochrome P450 (32.38%)
- Microsome (31.97%)
What were the highlights of his more recent work (between 2003-2020)?
- Biochemistry (53.28%)
- Pharmacology (15.98%)
- Phenethyl isothiocyanate (3.69%)
In recent papers he was focusing on the following fields of study:
Costas Ioannides mostly deals with Biochemistry, Pharmacology, Phenethyl isothiocyanate, Glutathione and Cytochrome P450.
His study in Biochemistry focuses on Carcinogen, Enzyme, Metabolism, Enzyme inducer and Sulforaphane.
His Enzyme inducer research incorporates elements of Microsome, Cytochrome b5, In vitro system, Barbiturate and Biphenyl compound.
His study in the field of Diazepam is also linked to topics like Hcmec d3.
His Glutathione research is multidisciplinary, relying on both Epoxide hydrolase and CYP1A2.
His Cytochrome P450 research integrates issues from Metabolic pathway, Stereochemistry, Incubation and Anthracene.
Between 2003 and 2020, his most popular works were:
- Mechanism of induction of hepatic microsomal drug metabolizing enzymes by a series of barbiturates. (140 citations)
- Absolute bioavailability and dose-dependent pharmacokinetic behaviour of dietary doses of the chemopreventive isothiocyanate sulforaphane in rat (107 citations)
- Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity (66 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Biochemistry
- Metabolism
Costas Ioannides spends much of his time researching Isothiocyanate, Biochemistry, Pharmacology, Enzyme inducer and Glutathione.
His Biochemistry study focuses mostly on Biphenyl compound, Microsome, Cytochrome and Cytochrome b5.
His Pharmacology study integrates concerns from other disciplines, such as Metabolism and CYP1A2.
Costas Ioannides has included themes like Transferase, Enzyme, Benzopyrene, Glutathione S-transferase and Barbiturate in his Metabolism study.
His Enzyme inducer research includes themes of CYP3A, Cytochrome P450, CYP2E1 and Incubation.
His research in Glutathione intersects with topics in Epoxide hydrolase and Pyrene.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
