Costas Ioannides

Overview

Best Publications

• Interaction of a series of nitriles with the alcohol-inducible isoform of P450: Computer analysis of structure—activity relationships

  D. F. V. Lewis;C. Ioannides;D. V. Parke

  665
  Citations

• Pharmacokinetic interactions between herbal remedies and medicinal drugs.

  Ioannides C

  322
  Citations

• The cytochrome P450 I gene family of microsomal hemoproteins and their role in the metabolic activation of chemicals.

  C. Ioannides;D. V. Parke

  322
  Citations

• Cytochromes P450 in the Bioactivation of Chemicals

  Costas Ioannides;David F V Lewis

  294
  Citations

• Mechanism of induction of hepatic microsomal drug metabolizing enzymes by a series of barbiturates.

  Costas Ioannides;Dennis V. Parke

  218
  Citations

• Absolute bioavailability and dose-dependent pharmacokinetic behaviour of dietary doses of the chemopreventive isothiocyanate sulforaphane in rat

  Natalya Hanlon;Nick Coldham;Adriana Gielbert;Nikolai Kuhnert

  183
  Citations

• Induction of Cytochrome P4501 as an Indicator of Potential Chemical Carcinogenesis

  C. Ioannides;D. V. Parke

  183
  Citations

• The cytochromes P-448—A unique family of enzymes involved in chemical toxicity and carcinogenesis

  Costas Ioannides;Dennis V. Parke

  173
  Citations

• Molecular dimensions of the substrate binding site of cytochrome P-448.

  David F.V. Lewis;Costas Ioannides;Dennis V. Parke

  168
  Citations

• CYTOCHROMES P450 AND SPECIES DIFFERENCES IN XENOBIOTIC METABOLISM AND ACTIVATION OF CARCINOGEN

  David F. V. Lewis;Costas Ioannides;Dennis V. Parke

  165
  Citations

• Interactions of imidazole antifungal agents with purified cytochrome P-450 proteins.

  A.D. Rodrigues;G.G. Gibson;C. Ioannides;D.V. Parke

  165
  Citations

• CYTOCHROME-P-448 AND THE ACTIVATION OF TOXIC-CHEMICALS AND CARCINOGENS

  C Ioannides;P Y Lum;D V Parke

  144
  Citations

• DETERMINATION OF CYTOCHROME-P-448 ACTIVITY IN BIOLOGICAL TISSUES

  C E Phillipson;P M M Godden;P Y Lum;C Ioannides

  139
  Citations

• Safrole: Its metabolism, carcinogenicity and interactions with cytochrome P-450

  C. Ioannides;M. Delaforge;D.V. Parke

  134
  Citations

• THE ROLE OF NUTRITION IN TOXICOLOGY

  Dennis V. Parke;Costas Ioannides

  134
  Citations

• THE 1990 PHARMACEUTICAL-MANUFACTURERS-ASSOCIATION-OF-CANADA KEYNOTE LECTURE - THE ROLE OF THE CYTOCHROMES-P450 IN THE DETOXICATION AND ACTIVATION OF DRUGS AND OTHER CHEMICALS

  Dennis V. Parke;Costas Ioannides;David F. V. Lewis

  133
  Citations

• Induction of cytochrome P450III and P450IV family proteins in streptozotocin-induced diabetes.

  C R Barnett;G G Gibson;C R Wolf;P R Flatt

  128
  Citations

• Selective induction of rat hepatic CYP1 and CYP4 proteins and of peroxisomal proliferation by green tea.

  A. Bu-Abbas;M.N. Clifford;R. Walker;C. Ioannides

  121
  Citations

• Effect of diet and nutrition on the expression of cytochromes P450.

  Costas Ioannides

  121
  Citations

• Marked antimutagenic potential of aqueous green tea extracts : mechanism of action

  A. Bu-Abbas;M.N. Clifford;R. Walker;C. Ioannides

  109
  Citations