Ronald G. Harvey

Overview

Best Publications

• Benzo(a)pyrene diol epoxides as intermediates in nucleic acid binding in vitro and in vivo.

  IB Weinstein;AM Jeffrey;KW Jennette;SH Blobstein

  724
  Citations

• Structures of benzo(a)pyrene–nucleic acid adducts formed in human and bovine bronchial explants

  A. M. Jeffrey;I. B. Weinstein;K. W. Jennette;K. Grzeskowiak

  409
  Citations

• Dehydrogenation of polycyclic hydroaromatic compounds

  Peter P. Fu;Ronald G. Harvey

  405
  Citations

• BENZO(A)PYRENE-NUCLEIC ACID DERIVATIVE FOUND IN VIVO- STRUCTURE OF A BENZO(A)PYRENETETRAHYDRODIOL EPOXIDE-GUANOSINE ADDUCT

  A. M. Jeffrey;K. W. Jennette;S. H. Blobstein;I. B. Weinstein

  346
  Citations

• Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells.

  Nisha T. Palackal;Seon Hwa Lee;Ronald G. Harvey;Ian A. Blair

  309
  Citations

• Generation of reactive oxygen species during the enzymatic oxidation of polycyclic aromatic hydrocarbon trans-dihydrodiols catalyzed by dihydrodiol dehydrogenase.

  T M Penning;S T Ohnishi;T Ohnishi;R G Harvey

  286
  Citations

• Nucleoside adducts from the in vitro reaction of benzo[a]pyrene-7,8-dihydrodiol 9,10-oxide or benzo[a]pyrene 4,5-oxide with nucleic acids.

  Jennette Kw;Jeffrey Am;Blobstein Sh;Beland Fa

  231
  Citations

• Intercalation and binding of carcinogenic hydrocarbon metabolites to nucleic acids

  Ronald G. Harvey;Nicholas E. Geacintov

  227
  Citations

• (+/-)-7alpha,8beta-dihydroxy-9beta,10beta-epoxy-7,8,9,10-tetrahydrobenzo(a)-pyrene is an intermediate in the metabolism and binding to DNA of benzo(a)pyrene.

  H. W. S. King;M. R. Osborne;F. A. Beland;R. G. Harvey

  200
  Citations

• Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: oxidation of trans-7, 8-dihydroxy-7,8-dihydrobenzo[a]pyrene to the activated o-quinone metabolite benzo[a]pyrene-7,8-dione.

  Michael E. Burczynski;Ronald G. Harvey;Trevor M. Penning

  188
  Citations

• Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine.

  Monique Cosman;Carlos de los Santos;Radovan Fiala;Brian E. Hingerty

  188
  Citations

• ABSOLUTE CONFIGURATION OF A RIBONUCLEIC ACID ADDUCT FORMED IN VIVO BY METABOLISM OF BENZO(A)PYRENE

  K. Nakanishi;H. Kasai;H. Cho;R. G. Harvey

  188
  Citations

• The reaction of (±)-7α, 8β-dihydroxy-9β, 10β-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene with dna

  M. R. Osborne;P. Brookes;F. A. Beland;R. G. Harvey

  178
  Citations

• Regio- and stereospecificity of homogeneous 3 alpha-hydroxysteroid-dihydrodiol dehydrogenase for trans-dihydrodiol metabolites of polycyclic aromatic hydrocarbons.

  T E Smithgall;R G Harvey;T M Penning

  170
  Citations

• The ubiquitous aldehyde reductase (AKR1A1) oxidizes proximate carcinogen trans-dihydrodiols to o-quinones: potential role in polycyclic aromatic hydrocarbon activation.

  Nisha T. Palackal;Michael E. Burczynski;Ronald G. Harvey;Trevor M. Penning

  167
  Citations

• Reactivity of benzo[a]pyrene-7,8-dione with DNA. Evidence for the formation of deoxyguanosine adducts

  Magang Shou;Ronald G. Harvey;Trevor M. Penning

  165
  Citations

• Comparison of the Cellular DNA-bound Products of Benzo(a)pyrene with the Products Formed by the Reaction of Benzo(a)pyrene-4,5-oxide with DNA

  William M. Baird;Ronald G. Harvey;Peter Brookes

  165
  Citations

• A new coumarin synthesis and its utilization for the synthesis of polycyclic coumarin compounds with anticarcinogenic properties

  Ronald G. Harvey;Cecilia Cortez;T. P. Ananthanarayan;Sanford Schmolka

  164
  Citations

• A new general synthesis of polycyclic aromatic compounds based on enamine chemistry

  Ronald G. Harvey;John Pataki;Cecilia Cortez;Pasquale Di Raddo

  162
  Citations

• CYTOTOXICITY AND MUTAGENICITY OF POLYCYCLIC AROMATIC HYDROCARBON O-QUINONES PRODUCED BY DIHYDRODIOL DEHYDROGENASE

  Lynn Flowers-Geary;Wendy Bleczinski;Ronald G. Harvey;Trevor M. Penning

  161
  Citations

• Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells

  Jong-Heum Park;Dipti Mangal;Kirk A. Tacka;Amy M. Quinn

  161
  Citations