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Chemistry

D-Index
70
Citations
20706
World Ranking
5777
National Ranking
1776

Overview

Haruhiko Yagi is affiliated with the National Institutes of Health in the United States. Their research intersects multiple areas within medicine and biochemistry, genetics, and molecular biology.

The scientist's work primarily focuses on several key topics:

  • Endoplasmic Reticulum Stress and Disease
  • Liver Disease Diagnosis and Treatment
  • Adipose Tissue and Metabolism

Main fields of study associated with Yagi's publications include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Further specialization is evident in the following subfields:

  • Cell Biology
  • Epidemiology
  • Physiology

Yagi has contributed research to the venue Stem Cell Research & Therapy, with at least one notable publication.

Their recent paper is titled "Therapeutic effects of adipose tissue-derived mesenchymal stem cells on ER stress in a murine model of metabolic dysfunction-associated steatohepatitis: an in vivo and in vitro study," published in 2025 in Stem Cell Research & Therapy.

Frequent collaborators include:

  • Norihiko Ogawa
  • Akihiro Seki
  • Alessandro Nasti
  • Masatoshi Yamato
  • Hiiro Inui

Best Publications

  • Foxp3+CD25+CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease

    Shimon Sakaguchi;Masahiro Ono;Ruka Setoguchi;Haruhiko Yagi

  • Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer.

    Junzo Hamanishi;Masaki Mandai;Masashi Iwasaki;Taku Okazaki

  • Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

    Haruhiko Yagi;Takashi Nomura;Kyoko Nakamura;Sayuri Yamazaki

  • Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

    M K Buening;P G Wislocki;W Levin;H Yagi

  • Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.

    A W Wood;W Levin;A Y Lu;H Yagi

  • Binding of benzo[a]pyrene 7,8-diol-9,10-epoxides to DNA, RNA, and protein of mouse skin occurs with high stereoselectivity

    Masato Koreeda;Patrick D. Moore;Peter G. Wislocki;Wayne Levin

  • Inhibition of the Mutagenicity of Bay-Region Diol Epoxides of Polycyclic Aromatic Hydrocarbons by Naturally Occurring Plant Phenols: Exceptional Activity of Ellagic Acid

    Alexander W. Wood;Mou-Tuan Huang;Richard L. Chang;Harold L. Newmark

  • Marked Differences in the Skin Tumor-initiating Activities of the Optical Enantiomers of the Diastereomeric Benzo(a)pyrene 7,8-Diol-9,10-Epoxides

    T. J. Slaga;W. J. Bracken;G. Gleason;W. Levin

  • Tumorigenicity studies with diol-epoxides of benzo(a)pyrene which indicate that (+/-)-trans-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene is an ultimate carcinogen in newborn mice.

    Jaime Kapitulnik;Peter G. Wislocki;Wayne Levin;Haruhiko Yagi

  • Metabolism of benzo[a]pyrene: conversion of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to highly mutagenic 7,8-diol-9,10-epoxides

    D. R. Thakker;H. Yagi;A. Y.H. Lu;W. Levin

  • Metabolism of benzo[a]pyrene. VI. Stereoselective metabolism of benzo[a]pyrene and benzo[a]pyrene 7,8-dihydrodiol to diol epoxides.

    D.R. Thakker;H. Yagi;H. Akagi;M. Koreeda

  • BENZO(A)PYRENE 7,8-DIHYDRODIOL IS MORE CARCINOGENIC THAN BENZO(A)PYRENE IN NEWBORN MICE

    J. Kapitulnik;W. Levin;A. H. Conney;H. Yagi

  • Effects of Inducers and Epoxide Hydrase on the Metabolism of Benzo[a]pyrene by Liver Microsomes and a Reconstituted System: Analysis by High Pressure Liquid Chromatography

    Gerald Holder;Haruhiko Yagi;Patrick Dansette;Donald M. Jerina

  • DIHYDRODIOLS FROM ANTHRACENE AND PHENANTHRENE

    D. M. Jerina;H. Selander;H. Yagi;M. C. Wells

  • Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by phenolic plant flavonoids

    Mou-Tuan Huang;Alexander W. Wood;Harold L. Newmark;Jane.M. Sayer

  • High mutagenicity and toxicity of a diol epoxide derived from benzo(a)pyrene.

    P.G. Wislocki;A.W. Wood;R.L. Chang;W. Levin

  • Differences in mutagenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides.

    Wood Aw;Chang Rl;Levin W;Yagi H

  • SYNTHESIS AND REACTIONS OF THE HIGHLY MUTAGENIC 7,8‐DIOL 9,10‐EPOXIDES OF THE CARCINOGEN BENZO(A)PYRENE

    H. Yagi;D. R. Thakker;O. Hernandez;M. Koreeda

  • Mutagenicity and Cytotoxicity of Benzo(a)pyrene Arene Oxides, Phenols, Quinones, and Dihydrodiols in Bacterial and Mammalian Cells

    Wislocki Pg;Wood Aw;Chang Rl;Levin W

  • Alkylation of polyguanylic acid at the 2-amino group and phosphate by the potent mutagen (+/-)-7beta,8alpha-dihydroxy-9beta,10beta-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.

    Masato Koreeda;Patrick D. Moore;Haruhiko Yagi;Herman J. C. Yeh

Frequent Co-Authors

Donald M. Jerina
Donald M. Jerina National Institutes of Health
Allan H. Conney
Allan H. Conney Rutgers, The State University of New Jersey
Jane M. Sayer
Jane M. Sayer National Institutes of Health
Wayne Levin
Wayne Levin Roche (Switzerland)
Dhiren R. Thakker
Dhiren R. Thakker University of North Carolina at Chapel Hill
Anthony Dipple
Anthony Dipple National Institutes of Health
Paul E. Thomas
Paul E. Thomas Rutgers, The State University of New Jersey
Patrick M. Dansette
Patrick M. Dansette Université Paris Cité
Dene E. Ryan
Dene E. Ryan Roche (Switzerland)
Derek R. Boyd
Derek R. Boyd Queen's University Belfast

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