What is he best known for?
The fields of study he is best known for:
Paul E. Thomas spends much of his time researching Cytochrome, Biochemistry, Microsome, Molecular biology and Cytochrome P450.
His Cytochrome research is multidisciplinary, relying on both Hemeprotein, Isozyme, Ouchterlony double immunodiffusion and Hydroxylation.
His studies link Chromatography with Biochemistry.
The various areas that Paul E. Thomas examines in his Microsome study include Enzyme inducer, Demethylation and Metabolism.
Paul E. Thomas interconnects Phenobarbital, Radial immunodiffusion, Monospecific antibody, Immunodiffusion and Peptide in the investigation of issues within Molecular biology.
His Cytochrome P450 study combines topics in areas such as Antibody and Monoclonal antibody.
His most cited work include:
- An improved staining procedure for the detection of the peroxidase activity of cytochrome P-450 on sodium dodecyl sulfate polyacrylamide gels. (925 citations)
- Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene. (543 citations)
- Characterization of the Oxidative Metabolites of 17β-Estradiol and Estrone Formed by 15 Selectively Expressed Human Cytochrome P450 Isoforms (360 citations)
What are the main themes of his work throughout his whole career to date?
Paul E. Thomas mostly deals with Biochemistry, Microsome, Cytochrome, Cytochrome P450 and Molecular biology.
His Biochemistry study frequently links to related topics such as Ouchterlony double immunodiffusion.
As a member of one scientific family, Paul E. Thomas mostly works in the field of Microsome, focusing on Isozyme and, on occasion, Polyclonal antibodies.
His Cytochrome study combines topics from a wide range of disciplines, such as Hemeprotein, Cytochrome c, Stereochemistry and Hydroxylation.
His study in Cytochrome P450 is interdisciplinary in nature, drawing from both Phenobarbital, Pharmacology and Enzyme inducer.
His Molecular biology research includes elements of Epitope, Monospecific antibody, Antibody, Monoclonal antibody and Messenger RNA.
He most often published in these fields:
- Biochemistry (56.86%)
- Microsome (50.49%)
- Cytochrome (46.08%)
What were the highlights of his more recent work (between 1997-2016)?
- Internal medicine (24.51%)
- Endocrinology (24.02%)
- Biochemistry (56.86%)
In recent papers he was focusing on the following fields of study:
Paul E. Thomas focuses on Internal medicine, Endocrinology, Biochemistry, Molecular biology and Toxicity.
His research integrates issues of Downregulation and upregulation, Isozyme and Pharmacology in his study of Internal medicine.
Endocrinology is closely attributed to Microsome in his study.
Paul E. Thomas combines subjects such as Precipitin, Cytochrome c, Cytochrome c peroxidase and Hemeprotein with his study of Microsome.
The Biochemistry study combines topics in areas such as Monoclonal antibody and In vivo.
His biological study spans a wide range of topics, including Immunohistochemistry, Amino acid and Epitope, Epitope mapping.
Between 1997 and 2016, his most popular works were:
- Characterization of the Oxidative Metabolites of 17β-Estradiol and Estrone Formed by 15 Selectively Expressed Human Cytochrome P450 Isoforms (360 citations)
- Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents. (247 citations)
- Comparative pharmacodynamics of CYP2B induction by DDT, DDE, and DDD in male rat liver and cultured rat hepatocytes. (67 citations)
In his most recent research, the most cited papers focused on:
Paul E. Thomas mostly deals with Internal medicine, Endocrinology, Cytochrome P450, Enzyme inducer and Molecular biology.
His studies deal with areas such as Estrogen receptor alpha and Proliferating cell nuclear antigen as well as Endocrinology.
Paul E. Thomas has researched Cytochrome P450 in several fields, including Estrone, Pharmacodynamics and Toxicokinetics.
His work in Enzyme inducer addresses subjects such as Western blot, which are connected to disciplines such as Northern blot, Microsome, Biological activity and Gene product.
His Molecular biology study incorporates themes from Electrophoretic mobility shift assay and Regulation of gene expression.
His research on CYP1A2 concerns the broader Biochemistry.
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