Anthony Y. H. Lu

Overview

Best Publications

• Inhibition and Induction of Cytochrome P450 and the Clinical Implications

  Jiunn H. Lin;Anthony Y. H. Lu

  1170
  Citations

• Role of Hemoprotein P-450 in Fatty Acid ω-Hydroxylation in a Soluble Enzyme System from Liver Microsomes

  Anthony Y. H. Lu;Minor J. Coon

  895
  Citations

• Resolution of the Cytochrome P-450-containing ω-Hydroxylation System of Liver Microsomes into Three Components

  Anthony Y. H. Lu;Karen W. Junk;Minor J. Coon

  835
  Citations

• Phosphatidylcholine Requirement in the Enzymatic Reduction of Hemoprotein P-450 and in Fatty Acid, Hydrocarbon, and Drug Hydroxylation

  Henry W. Strobel;Anthony Y. H. Lu;Joanne Heidema;Minor J. Coon

  655
  Citations

• Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. II. Role of the cytochrome P-450 and P-448 fractions in drug and steroid hydroxylations.

  Anthony Y. H. Lu;Ronald Kuntzman;Susan West;Martin Jacobson

  503
  Citations

• Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.

  A W Wood;W Levin;A Y Lu;H Yagi

  438
  Citations

• Partial purification of cytochromes P-450 and P-448 from rat liver microsomes.

  Anthony Y.H. Lu;Wayne Levin

  394
  Citations

• Interindividual variability in inhibition and induction of cytochrome P450 enzymes.

  Jiunn H Lin;Anthony Yh Lu

  388
  Citations

• Metabolism of benzo[a]pyrene. VI. Stereoselective metabolism of benzo[a]pyrene and benzo[a]pyrene 7,8-dihydrodiol to diol epoxides.

  D.R. Thakker;H. Yagi;H. Akagi;M. Koreeda

  317
  Citations

• The resolution and reconstitution of the liver microsomal hydroxylation system.

  Anthony Y.H. Lu;Wayne Levin

  315
  Citations

• Lipid peroxidation and the degradation of cytochrome P-450 heme.

  Wayne Levin;Anthony Y.H. Lu;Martin Jacobson;Ronald Kuntzman

  304
  Citations

• Reconstituted Liver Microsomal Enzyme System That Hydroxylates Drugs, Other Foreign Compounds, and Endogenous Substrates VI. DIFFERENT SUBSTRATE SPECIFICITIES OF THE CYTOCHROME P450 FRACTIONS FROM CONTROL AND PHENOBARBITAL-TREATED RATS

  Anthony Y.H. Lu;Wayne Levin;Susan B. West;Martin Jacobson

  295
  Citations

• Effects of Inducers and Epoxide Hydrase on the Metabolism of Benzo[a]pyrene by Liver Microsomes and a Reconstituted System: Analysis by High Pressure Liquid Chromatography

  Gerald Holder;Haruhiko Yagi;Patrick Dansette;Donald M. Jerina

  292
  Citations

• Rat liver glutathione S-transferases. Complete nucleotide sequence of a glutathione S-transferase mRNA and the regulation of the Ya, Yb, and Yc mRNAs by 3-methylcholanthrene and phenobarbital.

  C B Pickett;C A Telakowski-Hopkins;G J Ding;L Argenbright

  290
  Citations

• CYP1A Induction and Human Risk Assessment: An Evolving Tale of in Vitro and in Vivo Studies

  Qiang Ma;Anthony Y. H. Lu

  290
  Citations

• Biotransformation of lovastatin. IV. Identification of cytochrome P450 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes.

  R. W. Wang;P. H. Kari;A. Y. H. Lu;P. E. Thomas

  279
  Citations

• Highly purified cytochrome P-448 and P=450 from rat liver microsomes.

  Dene Ryan;Anthony Y.H. Lu;Joseph Kawalek;Susan B. West

  271
  Citations

• Pregnenolone-16 -carbonitrile: a new type of inducer of drug-metabolizing enzymes

  A Y Lu;A Somogyi;S West;R Kuntzman

  270
  Citations

• The environmental impact of the use of ivermectin: environmental effects and fate

  Bruce A. Halley;Theodore A. Jacob;Anthony Y.H. Lu

  254
  Citations

• Multiple Forms of Rat Liver Cytochrome P-450

  Paul E. Thomas;Anthony Y. H. Lu;Dene Ryan;Susan B. West

  1
  Citations